3FAYA

Crystal structure of the gap-related domain of iqgap1
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
379
structure length
379
Chain Sequence
ASKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Membrane protein
molecule keywords Ras GTPase-activating-like protein IQGAP1
publication title Crystal structure of the GTPase-activating protein-related domain from IQGAP1.
pubmed doi rcsb
source organism Homo sapiens
total genus 126
structure length 379
sequence length 379
ec nomenclature
pdb deposition date 2008-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00616 RasGAP GTPase-activator protein for Ras-like GTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.506.10 Mainly Alpha Orthogonal Bundle GTPase Activation - p120GAP; domain 1 GTPase Activation - p120gap; domain 1 3fayA00
1WERA 3SU8X 3HM6X 1NF1A 3BXJA 4M8MA 5E6PA 4M8NA 3IG3A 1WQ1G 3RYTA 3FAYA
chains in the Genus database with same CATH superfamily
1WERA 3SU8X 3HM6X 1NF1A 3BXJA 4M8MA 5E6PA 4M8NA 3IG3A 1WQ1G 3RYTA 3FAYA
chains in the Genus database with same CATH topology
1WERA 3SU8X 3HM6X 1NF1A 3BXJA 4M8MA 5E6PA 4M8NA 3IG3A 1WQ1G 3RYTA 3FAYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WER A;  3SU8 X;  3HM6 X;  1NF1 A;  3BXJ A;  4M8M A;  5E6P A;  4M8N A;  3IG3 A;  1WQ1 G;  3RYT A;  3FAY A; 
#chains in the Genus database with same CATH topology
 1WER A;  3SU8 X;  3HM6 X;  1NF1 A;  3BXJ A;  4M8M A;  5E6P A;  4M8N A;  3IG3 A;  1WQ1 G;  3RYT A;  3FAY A; 
#chains in the Genus database with same CATH homology
 1WER A;  3SU8 X;  3HM6 X;  1NF1 A;  3BXJ A;  4M8M A;  5E6P A;  4M8N A;  3IG3 A;  1WQ1 G;  3RYT A;  3FAY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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