3NQ0A

Crystal structure of tyrosinase from bacillus megaterium crystallized in the absence of zinc
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
283
structure length
283
Chain Sequence
KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHRWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Tyrosinase
publication title First structures of an active bacterial tyrosinase reveal copper plasticity.
pubmed doi rcsb
source organism Bacillus megaterium
total genus 95
structure length 283
sequence length 283
chains with identical sequence B
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2010-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 3nq0A00
1LNLA 2P3XA 1LLAA 3HHSB 1BT3A 3AWSA 3AX0A 1NOLA 3AWWA 5I3BA 1BUGA 2ZWDA 4P6TA 4J6VA 4HD6A 3WKYA 2ZMZA 4OUAB 3AWTA 1LL1A 4P6RA 1BT1A 1HC1A 5I38A 1WX5A 3AWXA 4J3RA 5CE9A 2Y9XA 1WX4A 2AHLA 2ZWFA 2ZWGA 4P6SA 3NM8A 3AWUA 2ZWEA 1WX2A 4Z10A 3WJMA 4J6TA 5I3AA 3AWVA 4Z0YA 4J3PA 1OXYA 1JS8A 1WXCA 3W6WA 3NQ5A 3NTMA 4J6UA 3W6QA 3GWJA 3AWZA 2AHKA 3NQ1A 3HHSA 2ZMYA 1HCYA 4HD4A 3WJMB 3AWYA 3NQ0A 4D87A 2ZMXA 1BT2A 2Y9WA 3NPYA 4L37B 4Z0ZA 4J3QA 4OUAA 4YZWA 3QJOA 4L37A 4HD7A
chains in the Genus database with same CATH superfamily
1LNLA 2P3XA 1LLAA 3HHSB 1BT3A 3AWSA 3AX0A 1NOLA 3AWWA 5I3BA 1BUGA 2ZWDA 4P6TA 4J6VA 4HD6A 3WKYA 2ZMZA 4OUAB 3AWTA 1LL1A 4P6RA 1BT1A 1HC1A 5I38A 1WX5A 3AWXA 4J3RA 5CE9A 2Y9XA 1WX4A 2AHLA 2ZWFA 2ZWGA 4P6SA 3NM8A 3AWUA 2ZWEA 1WX2A 4Z10A 3WJMA 4J6TA 5I3AA 3AWVA 4Z0YA 4J3PA 1OXYA 1JS8A 1WXCA 3W6WA 3NQ5A 3NTMA 4J6UA 3W6QA 3GWJA 3AWZA 2AHKA 3NQ1A 3HHSA 2ZMYA 1HCYA 4HD4A 3WJMB 3AWYA 3NQ0A 4D87A 2ZMXA 1BT2A 2Y9WA 3NPYA 4L37B 4Z0ZA 4J3QA 4OUAA 4YZWA 3QJOA 4L37A 4HD7A
chains in the Genus database with same CATH topology
1LNLA 2P3XA 1LLAA 3HHSB 1BT3A 3AWSA 3AX0A 1NOLA 3AWWA 5I3BA 1BUGA 2ZWDA 4P6TA 4J6VA 4HD6A 3WKYA 2ZMZA 4OUAB 3AWTA 1LL1A 4P6RA 1BT1A 1HC1A 5I38A 1WX5A 3AWXA 4J3RA 5CE9A 2Y9XA 1WX4A 2AHLA 2ZWFA 2ZWGA 4P6SA 3NM8A 3AWUA 2ZWEA 1WX2A 4Z10A 3WJMA 4J6TA 5I3AA 3AWVA 4Z0YA 4J3PA 1OXYA 1JS8A 1WXCA 3W6WA 3NQ5A 3NTMA 4J6UA 3W6QA 3GWJA 3AWZA 2AHKA 3NQ1A 3HHSA 2ZMYA 1HCYA 4HD4A 3WJMB 3AWYA 3NQ0A 4D87A 2ZMXA 1BT2A 2Y9WA 3NPYA 4L37B 4Z0ZA 4J3QA 4OUAA 4YZWA 3QJOA 4L37A 4HD7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LNL A;  2P3X A;  1LLA A;  3HHS B;  1BT3 A;  3AWS A;  3AX0 A;  1NOL A;  3AWW A;  5I3B A;  1BUG A;  2ZWD A;  4P6T A;  4J6V A;  4HD6 A;  3WKY A;  2ZMZ A;  4OUA B;  3AWT A;  1LL1 A;  4P6R A;  1BT1 A;  1HC1 A;  5I38 A;  1WX5 A;  3AWX A;  4J3R A;  5CE9 A;  2Y9X A;  1WX4 A;  2AHL A;  2ZWF A;  2ZWG A;  4P6S A;  3NM8 A;  3AWU A;  2ZWE A;  1WX2 A;  4Z10 A;  3WJM A;  4J6T A;  5I3A A;  3AWV A;  4Z0Y A;  4J3P A;  1OXY A;  1JS8 A;  1WXC A;  3W6W A;  3NQ5 A;  3NTM A;  4J6U A;  3W6Q A;  3GWJ A;  3AWZ A;  2AHK A;  3NQ1 A;  3HHS A;  2ZMY A;  1HCY A;  4HD4 A;  3WJM B;  3AWY A;  3NQ0 A;  4D87 A;  2ZMX A;  1BT2 A;  2Y9W A;  3NPY A;  4L37 B;  4Z0Z A;  4J3Q A;  4OUA A;  4YZW A;  3QJO A;  4L37 A;  4HD7 A; 
#chains in the Genus database with same CATH topology
 1LNL A;  2P3X A;  1LLA A;  3HHS B;  1BT3 A;  3AWS A;  3AX0 A;  1NOL A;  3AWW A;  5I3B A;  1BUG A;  2ZWD A;  4P6T A;  4J6V A;  4HD6 A;  3WKY A;  2ZMZ A;  4OUA B;  3AWT A;  1LL1 A;  4P6R A;  1BT1 A;  1HC1 A;  5I38 A;  1WX5 A;  3AWX A;  4J3R A;  5CE9 A;  2Y9X A;  1WX4 A;  2AHL A;  2ZWF A;  2ZWG A;  4P6S A;  3NM8 A;  3AWU A;  2ZWE A;  1WX2 A;  4Z10 A;  3WJM A;  4J6T A;  5I3A A;  3AWV A;  4Z0Y A;  4J3P A;  1OXY A;  1JS8 A;  1WXC A;  3W6W A;  3NQ5 A;  3NTM A;  4J6U A;  3W6Q A;  3GWJ A;  3AWZ A;  2AHK A;  3NQ1 A;  3HHS A;  2ZMY A;  1HCY A;  4HD4 A;  3WJM B;  3AWY A;  3NQ0 A;  4D87 A;  2ZMX A;  1BT2 A;  2Y9W A;  3NPY A;  4L37 B;  4Z0Z A;  4J3Q A;  4OUA A;  4YZW A;  3QJO A;  4L37 A;  4HD7 A; 
#chains in the Genus database with same CATH homology
 1LNL A;  2P3X A;  1LLA A;  3HHS B;  1BT3 A;  3AWS A;  3AX0 A;  1NOL A;  3AWW A;  5I3B A;  1BUG A;  2ZWD A;  4P6T A;  4J6V A;  4HD6 A;  3WKY A;  2ZMZ A;  4OUA B;  3AWT A;  1LL1 A;  4P6R A;  1BT1 A;  1HC1 A;  5I38 A;  1WX5 A;  3AWX A;  4J3R A;  5CE9 A;  2Y9X A;  1WX4 A;  2AHL A;  2ZWF A;  2ZWG A;  4P6S A;  3NM8 A;  3AWU A;  2ZWE A;  1WX2 A;  4Z10 A;  3WJM A;  4J6T A;  5I3A A;  3AWV A;  4Z0Y A;  4J3P A;  1OXY A;  1JS8 A;  1WXC A;  3W6W A;  3NQ5 A;  3NTM A;  4J6U A;  3W6Q A;  3GWJ A;  3AWZ A;  2AHK A;  3NQ1 A;  3HHS A;  2ZMY A;  1HCY A;  4HD4 A;  3WJM B;  3AWY A;  3NQ0 A;  4D87 A;  2ZMX A;  1BT2 A;  2Y9W A;  3NPY A;  4L37 B;  4Z0Z A;  4J3Q A;  4OUA A;  4YZW A;  3QJO A;  4L37 A;  4HD7 A; 
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similar chains in the Genus database (?% sequence similarity)
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