3REMA

Structure of the isochorismate-pyruvate lyase from pseudomonas aerugionsa with bound salicylate and pyruvate
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
97
structure length
97
Chain Sequence
KTPEDCTGLADIREAIDRIDLDIVQALGRRMDYVKAASRFKASEAAIPAPERVAAMLPERARWAEENGLDAPFVEGLFAQIIHWYIAEQIKYWRQTR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Salicylate biosynthesis protein pchB
publication title pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 36
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature ec 4.2.99.21: Isochorismate lyase.
pdb deposition date 2011-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01817 CM_2 Chorismate mutase type II
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.59.10 Mainly Alpha Up-down Bundle Chorismate Mutase Domain, subunit A Chorismate mutase 3remA00
3RMIA 2H9CA 5CKXC 2W19C 1ECMA 3REMA 3HGXA 2D8EA 2H9DA 2D8DA 3HGWA 2W1AC 3NVTA 2GTVX 2VKLA 3RETA 2QBVA 3TFCA 1YBZA
chains in the Genus database with same CATH superfamily
2E21A 3RMIA 3A2KA 2H9CA 5CKXC 1WY5A 2W19C 1ECMA 3REMA 3HGXA 2D8EA 2H9DA 1NI5A 2D8DA 3HGWA 2W1AC 3NVTA 2GTVX 2VKLA 3RETA 2QBVA 2E89A 3TFCA 1YBZA
chains in the Genus database with same CATH topology
3RMIA 2H9CA 5CKXC 2W19C 1ECMA 3REMA 3HGXA 2D8EA 2H9DA 2D8DA 3HGWA 2W1AC 3NVTA 2GTVX 2VKLA 3RETA 2QBVA 3TFCA 1YBZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RMI A;  2H9C A;  5CKX C;  2W19 C;  1ECM A;  3REM A;  3HGX A;  2D8E A;  2H9D A;  2D8D A;  3HGW A;  2W1A C;  3NVT A;  2GTV X;  2VKL A;  3RET A;  2QBV A;  3TFC A;  1YBZ A; 
#chains in the Genus database with same CATH topology
 2E21 A;  3RMI A;  3A2K A;  2H9C A;  5CKX C;  1WY5 A;  2W19 C;  1ECM A;  3REM A;  3HGX A;  2D8E A;  2H9D A;  1NI5 A;  2D8D A;  3HGW A;  2W1A C;  3NVT A;  2GTV X;  2VKL A;  3RET A;  2QBV A;  2E89 A;  3TFC A;  1YBZ A; 
#chains in the Genus database with same CATH homology
 3RMI A;  2H9C A;  5CKX C;  2W19 C;  1ECM A;  3REM A;  3HGX A;  2D8E A;  2H9D A;  2D8D A;  3HGW A;  2W1A C;  3NVT A;  2GTV X;  2VKL A;  3RET A;  2QBV A;  3TFC A;  1YBZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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