3ZFNA

Crystal structure of product-like, processed n-terminal protease npro
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
148
structure length
148
Chain Sequence
MEPLYDKNGAVLFGEPSDTHPQSTLKLPHPRGEKEVIVGIRDLPRKGDCRTGNRLGPVSGLFVKPGPVFYQDYSGPVYHRAPLEQFKQAPMCEVTKRIGRVTGSDGNLYHMYVCTDGCILVKTAKREGQDVLKWVYNVLDSPIWVTSC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords N-TERMINAL PROTEASE NPRO
publication title Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis
pubmed doi rcsb
source organism Pestivirus strain d32/00_hobi
total genus 32
structure length 148
sequence length 148
ec nomenclature ec 3.4.22.-:
pdb deposition date 2012-12-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.140.40 Mainly Beta Roll Spermidine Synthase; Chain: A, domain 2 Spermidine Synthase; Chain: A, domain 2 3zfnA02
4H9KA 3ZFOA 3ZFRA 3ZFPA 3ZFTA 4H9JA 3ZFUA 3ZFNA 3ZFQA
chains in the Genus database with same CATH superfamily
1UIRA 3BWCA 1TVFA 2PT6A 3HUMA 2B2CA 2O06A 3ZFNA 2CMHA 4YV0A 4H9KA 4CWAA 1INLA 4UOEA 4BP1A 3C6KA 4YUZA 1JQ3A 1IY9A 4BP3A 4F98A 3HUNA 2I7CA 2E5WA 2CMGA 3ZFUA 4YUWA 3C6MA 3RIEA 2Q41A 2PSSA 2O0LA 4YUYA 4YUVA 1XJ5A 4CXMA 3RW9A 2O07A 3MFDA 2PT9A 3O4FA 3ZFRA 4H9JA 3ZFTA 2O05A 4YV2A 2PWPA 3ZFOA 4YUXA 5B1SA 3B7PA 4YV1A 2HTEA 3ZFPA 3ANXA 2ZSUA 3BWBA 1MJFA 3ZFQA
chains in the Genus database with same CATH topology
4H9KA 3ZFOA 3MFDA 3ZFRA 3ZFPA 4H9JA 3ZFTA 4F98A 3ZFUA 3ZFNA 3ZFQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H9K A;  3ZFO A;  3ZFR A;  3ZFP A;  3ZFT A;  4H9J A;  3ZFU A;  3ZFN A;  3ZFQ A; 
#chains in the Genus database with same CATH topology
 1UIR A;  3BWC A;  1TVF A;  2PT6 A;  3HUM A;  2B2C A;  2O06 A;  3ZFN A;  2CMH A;  4YV0 A;  4H9K A;  4CWA A;  1INL A;  4UOE A;  4BP1 A;  3C6K A;  4YUZ A;  1JQ3 A;  1IY9 A;  4BP3 A;  4F98 A;  3HUN A;  2I7C A;  2E5W A;  2CMG A;  3ZFU A;  4YUW A;  3C6M A;  3RIE A;  2Q41 A;  2PSS A;  2O0L A;  4YUY A;  4YUV A;  1XJ5 A;  4CXM A;  3RW9 A;  2O07 A;  3MFD A;  2PT9 A;  3O4F A;  3ZFR A;  4H9J A;  3ZFT A;  2O05 A;  4YV2 A;  2PWP A;  3ZFO A;  4YUX A;  5B1S A;  3B7P A;  4YV1 A;  2HTE A;  3ZFP A;  3ANX A;  2ZSU A;  3BWB A;  1MJF A;  3ZFQ A; 
#chains in the Genus database with same CATH homology
 4H9K A;  3ZFO A;  3MFD A;  3ZFR A;  3ZFP A;  4H9J A;  3ZFT A;  4F98 A;  3ZFU A;  3ZFN A;  3ZFQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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