4BSSC

Structure of the ectodomain of lgr5 in complex with r-spondin-1 (fu1fu2) in p21 crystal form
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
103
structure length
103
Chain Sequence
CAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5
publication title Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
pubmed doi rcsb
source organism Homo sapiens
total genus 14
structure length 103
sequence length 103
chains with identical sequence D, G, H
ec nomenclature
pdb deposition date 2013-06-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.220.10 Mainly Beta Ribbon Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2 Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2 4bssC00
4XSSE 4C9RB 1YY9A 3U2PA 4KRPA 1M6BA 1MOXA 2A91A 4UFRB 4C9EB 3W11E 4BSOA 4HRNC 3LTFA 4KROA 3BE1A 3MZWA 3I2TA 1IVOA 3U9UE 3QWQA 3U7UA 3B2VA 3WLWA 4BSSC 4C9AB 4QXFC 4BSRC 4LEOC 4C9UB 3LTGA 1N8ZC 1NQLA 4C8WI 4BSPA 1N8YC 5J3HE 2AHXA 4KNGM 4LI2B 4CDKE 4BSUC 4C9VB 3P11A 4OGAE 4UV7A 4C99B 4C8VA 4XSTE 3NJPA 2HR7A 4P59A 4KT1E 1IGRA 3WSQA 3N85A 1S78A
chains in the Genus database with same CATH superfamily
4XSSE 4C9RB 1YY9A 3U2PA 4KRPA 1M6BA 1MOXA 2A91A 4UFRB 4C9EB 3W11E 4BSOA 4HRNC 3LTFA 4KROA 3BE1A 3MZWA 3I2TA 1IVOA 3U9UE 3QWQA 3U7UA 3B2VA 3WLWA 4BSSC 4C9AB 4QXFC 4BSRC 4LEOC 4C9UB 3LTGA 1N8ZC 1NQLA 4C8WI 4BSPA 1N8YC 5J3HE 2AHXA 4KNGM 4LI2B 4CDKE 4BSUC 4C9VB 3P11A 4OGAE 4UV7A 4C99B 4C8VA 4XSTE 3NJPA 2HR7A 4P59A 4KT1E 1IGRA 3WSQA 3N85A 1S78A
chains in the Genus database with same CATH topology
4XSSE 4C9RB 1YY9A 3U2PA 4KRPA 1M6BA 1MOXA 2A91A 4UFRB 4C9EB 3W11E 4BSOA 4HRNC 3LTFA 4KROA 3BE1A 3MZWA 3I2TA 1IVOA 3U9UE 3QWQA 3U7UA 3B2VA 3WLWA 4BSSC 4C9AB 4QXFC 4BSRC 4LEOC 4C9UB 3LTGA 1N8ZC 1NQLA 4C8WI 4BSPA 1N8YC 5J3HE 2AHXA 4KNGM 4LI2B 4CDKE 4BSUC 4C9VB 3P11A 4OGAE 4UV7A 4C99B 4C8VA 4XSTE 3NJPA 2HR7A 4P59A 4KT1E 1IGRA 3WSQA 3N85A 1S78A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XSS E;  4C9R B;  1YY9 A;  3U2P A;  4KRP A;  1M6B A;  1MOX A;  2A91 A;  4UFR B;  4C9E B;  3W11 E;  4BSO A;  4HRN C;  3LTF A;  4KRO A;  3BE1 A;  3MZW A;  3I2T A;  1IVO A;  3U9U E;  3QWQ A;  3U7U A;  3B2V A;  3WLW A;  4BSS C;  4C9A B;  4QXF C;  4BSR C;  4LEO C;  4C9U B;  3LTG A;  1N8Z C;  1NQL A;  4C8W I;  4BSP A;  1N8Y C;  5J3H E;  2AHX A;  4KNG M;  4LI2 B;  4CDK E;  4BSU C;  4C9V B;  3P11 A;  4OGA E;  4UV7 A;  4C99 B;  4C8V A;  4XST E;  3NJP A;  2HR7 A;  4P59 A;  4KT1 E;  1IGR A;  3WSQ A;  3N85 A;  1S78 A; 
#chains in the Genus database with same CATH topology
 4XSS E;  4C9R B;  1YY9 A;  3U2P A;  4KRP A;  1M6B A;  1MOX A;  2A91 A;  4UFR B;  4C9E B;  3W11 E;  4BSO A;  4HRN C;  3LTF A;  4KRO A;  3BE1 A;  3MZW A;  3I2T A;  1IVO A;  3U9U E;  3QWQ A;  3U7U A;  3B2V A;  3WLW A;  4BSS C;  4C9A B;  4QXF C;  4BSR C;  4LEO C;  4C9U B;  3LTG A;  1N8Z C;  1NQL A;  4C8W I;  4BSP A;  1N8Y C;  5J3H E;  2AHX A;  4KNG M;  4LI2 B;  4CDK E;  4BSU C;  4C9V B;  3P11 A;  4OGA E;  4UV7 A;  4C99 B;  4C8V A;  4XST E;  3NJP A;  2HR7 A;  4P59 A;  4KT1 E;  1IGR A;  3WSQ A;  3N85 A;  1S78 A; 
#chains in the Genus database with same CATH homology
 4XSS E;  4C9R B;  1YY9 A;  3U2P A;  4KRP A;  1M6B A;  1MOX A;  2A91 A;  4UFR B;  4C9E B;  3W11 E;  4BSO A;  4HRN C;  3LTF A;  4KRO A;  3BE1 A;  3MZW A;  3I2T A;  1IVO A;  3U9U E;  3QWQ A;  3U7U A;  3B2V A;  3WLW A;  4BSS C;  4C9A B;  4QXF C;  4BSR C;  4LEO C;  4C9U B;  3LTG A;  1N8Z C;  1NQL A;  4C8W I;  4BSP A;  1N8Y C;  5J3H E;  2AHX A;  4KNG M;  4LI2 B;  4CDK E;  4BSU C;  4C9V B;  3P11 A;  4OGA E;  4UV7 A;  4C99 B;  4C8V A;  4XST E;  3NJP A;  2HR7 A;  4P59 A;  4KT1 E;  1IGR A;  3WSQ A;  3N85 A;  1S78 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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