4F7GB

Crystal structure of talin autoinhibition complex
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
170
structure length
170
Chain Sequence
APGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Cell adhesion
molecule keywords Talin-1
publication title A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
pubmed doi rcsb
source organism Mus musculus
total genus 73
structure length 170
sequence length 170
ec nomenclature
pdb deposition date 2012-05-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 4f7gB00
3DYJA 3AY5A 5FZTA 4F7GB 2KGXA 2L7NA 2L10A 3FYQA 2KVPA 1SJ8A 2X0CA 4W8PA 1SJ7A 2KBBA
chains in the Genus database with same CATH superfamily
3AY5A 5JDFA 3V5UA 3M1CA 4W8PA 5HXRA 5JDGA 5JDQA 5HXEA 2KBBA 3DYJA 5FZTA 3PF0A 4F7GB 2KGXA 5HYAA 5JDNA 2L10A 3FYQA 4ONRA 2XQYA 2X0CA 5JDLA 3WURA 3AT7A 3WSCA 2L7NA 5JDHA 5HXHA 2KVPA 2MTCA 3VJZA 1SJ8A 4ECGA 5HWXA 1SJ7A 5HXCA 5T1DA 5HXSA 2LQUA 5JDMA 3PHF1 4BGOA 5HWYA 3V5SA
chains in the Genus database with same CATH topology
3DYJA 3AY5A 5FZTA 4F7GB 2KGXA 2L7NA 2L10A 3FYQA 2KVPA 1SJ8A 2X0CA 4W8PA 1SJ7A 2KBBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYJ A;  3AY5 A;  5FZT A;  4F7G B;  2KGX A;  2L7N A;  2L10 A;  3FYQ A;  2KVP A;  1SJ8 A;  2X0C A;  4W8P A;  1SJ7 A;  2KBB A; 
#chains in the Genus database with same CATH topology
 3AY5 A;  5JDF A;  3V5U A;  3M1C A;  4W8P A;  5HXR A;  5JDG A;  5JDQ A;  5HXE A;  2KBB A;  3DYJ A;  5FZT A;  3PF0 A;  4F7G B;  2KGX A;  5HYA A;  5JDN A;  2L10 A;  3FYQ A;  4ONR A;  2XQY A;  2X0C A;  5JDL A;  3WUR A;  3AT7 A;  3WSC A;  2L7N A;  5JDH A;  5HXH A;  2KVP A;  2MTC A;  3VJZ A;  1SJ8 A;  4ECG A;  5HWX A;  1SJ7 A;  5HXC A;  5T1D A;  5HXS A;  2LQU A;  5JDM A;  3PHF 1;  4BGO A;  5HWY A;  3V5S A; 
#chains in the Genus database with same CATH homology
 3DYJ A;  3AY5 A;  5FZT A;  4F7G B;  2KGX A;  2L7N A;  2L10 A;  3FYQ A;  2KVP A;  1SJ8 A;  2X0C A;  4W8P A;  1SJ7 A;  2KBB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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