4IHEA

Crystal structure of uncleaved thnt t282a
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
372
structure length
358
Chain Sequence
GGVPGPHNGLTDVPGVRVGHAGRTGDGWLTGVTVVLAPPGGAVAAVDVRGGGPGTRETDALDPRNLVQTIDAVVLTGGSAFGLDAAGGVAAWLEEQGRGFPVGADPSQVVPVVPAAALFDLGRGGTWRARPDAALGRAAVEAAAARPEGDPVEQGGVGAGTGAVVGGLKGGIGTASVVLDSGATVAALAAVNAAGSAVDPATGVLYGARTGLPGEFAGYGVPDAIGADTHARARARLAEAAEETARRRAGGAATLNATLAVVATDATLTRAQAQKLAGTAHDGLARAVRPVHLLSDGDTVFALSTGRRPLLHLEAGALNEVLAAGADVLTRAVVHAVLAATGVDTPGGVHPSYRELYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords ThnT protein
publication title Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT.
pubmed doi rcsb
source organism Streptomyces cattleya
total genus 117
structure length 358
sequence length 372
chains with identical sequence B
ec nomenclature ec 3.5.1.92: Pantetheine hydrolase.
pdb deposition date 2012-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03576 Peptidase_S58 Peptidase family S58
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.70.12 Alpha Beta 4-Layer Sandwich L-amino peptidase D-ALA esterase/amidase L-amino peptidase D-ALA esterase/amidase 4iheA00
3S3UA 1VZ8A 3NDVA 3N5IA 2DRHA 2VZKA 1VRAA 3N33A 3TM2A 1VZ7A 3IT6A 4IHEA 3AXGA 3NFBA 4IHDA 2V4IA 1VZ6A 3TM1A 3N2WA 1B65A 3IT4A 2YEPA
chains in the Genus database with same CATH superfamily
3S3UA 1VZ8A 3NDVA 3N5IA 2DRHA 2VZKA 1VRAA 3N33A 3TM2A 1VZ7A 3IT6A 4IHEA 3AXGA 3NFBA 4IHDA 2V4IA 1VZ6A 3TM1A 3N2WA 1B65A 3IT4A 2YEPA
chains in the Genus database with same CATH topology
3S3UA 1VZ8A 3NDVA 3N5IA 2DRHA 2VZKA 1VRAA 3N33A 3TM2A 1VZ7A 3IT6A 4IHEA 3AXGA 3NFBA 4IHDA 2V4IA 1VZ6A 3TM1A 3N2WA 1B65A 3IT4A 2YEPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S3U A;  1VZ8 A;  3NDV A;  3N5I A;  2DRH A;  2VZK A;  1VRA A;  3N33 A;  3TM2 A;  1VZ7 A;  3IT6 A;  4IHE A;  3AXG A;  3NFB A;  4IHD A;  2V4I A;  1VZ6 A;  3TM1 A;  3N2W A;  1B65 A;  3IT4 A;  2YEP A; 
#chains in the Genus database with same CATH topology
 3S3U A;  1VZ8 A;  3NDV A;  3N5I A;  2DRH A;  2VZK A;  1VRA A;  3N33 A;  3TM2 A;  1VZ7 A;  3IT6 A;  4IHE A;  3AXG A;  3NFB A;  4IHD A;  2V4I A;  1VZ6 A;  3TM1 A;  3N2W A;  1B65 A;  3IT4 A;  2YEP A; 
#chains in the Genus database with same CATH homology
 3S3U A;  1VZ8 A;  3NDV A;  3N5I A;  2DRH A;  2VZK A;  1VRA A;  3N33 A;  3TM2 A;  1VZ7 A;  3IT6 A;  4IHE A;  3AXG A;  3NFB A;  4IHD A;  2V4I A;  1VZ6 A;  3TM1 A;  3N2W A;  1B65 A;  3IT4 A;  2YEP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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