4M62S

Ontogeny of recognition specificity and functionality for the anti-hiv neutralizing antibody 4e10
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
155
structure length
155
Chain Sequence
NAMQGIHFRRHYVRHLPKEVSQNDIIKALASPLINDGMVVSDFADHVITREQNFPTGLPVEPVGVAIPHTDSKYVRQNAISVGILAEPVNFEDAGGEPDPVPVRVVFMLALGNWFDITNVLWWIMDVIQDEDFMQQLLVMNDDEIYQSIYTRISE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords GEP2 FV light chain
publication title Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
pubmed doi rcsb
source organism Homo sapiens
total genus 45
structure length 155
sequence length 155
chains with identical sequence T
ec nomenclature
pdb deposition date 2013-08-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.930.10 Alpha Beta 3-Layer(aba) Sandwich Mannitol-specific EII; Chain A Mannitol-specific EII; Chain A 4m62S00
1HYNP 2OQTA 2OQ3A 3URRA 3T43A 1A3AA 3OXPA 4ODXX 4KY9A 2A0JA 1A6JA 4GQXA 3LF6A 4M62S 1J6TA 2FEWA 3BJVA 4M8QC 1XIZA
chains in the Genus database with same CATH superfamily
1HYNP 2OQTA 2OQ3A 3URRA 3T43A 1A3AA 3OXPA 4ODXX 4KY9A 2A0JA 1A6JA 4GQXA 3LF6A 4M62S 1J6TA 2FEWA 3BJVA 4M8QC 1XIZA
chains in the Genus database with same CATH topology
1HYNP 2OQTA 2OQ3A 3URRA 3T43A 1A3AA 3OXPA 4ODXX 4KY9A 2A0JA 1A6JA 4GQXA 3LF6A 4M62S 1J6TA 2FEWA 3BJVA 4M8QC 1XIZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HYN P;  2OQT A;  2OQ3 A;  3URR A;  3T43 A;  1A3A A;  3OXP A;  4ODX X;  4KY9 A;  2A0J A;  1A6J A;  4GQX A;  3LF6 A;  4M62 S;  1J6T A;  2FEW A;  3BJV A;  4M8Q C;  1XIZ A; 
#chains in the Genus database with same CATH topology
 1HYN P;  2OQT A;  2OQ3 A;  3URR A;  3T43 A;  1A3A A;  3OXP A;  4ODX X;  4KY9 A;  2A0J A;  1A6J A;  4GQX A;  3LF6 A;  4M62 S;  1J6T A;  2FEW A;  3BJV A;  4M8Q C;  1XIZ A; 
#chains in the Genus database with same CATH homology
 1HYN P;  2OQT A;  2OQ3 A;  3URR A;  3T43 A;  1A3A A;  3OXP A;  4ODX X;  4KY9 A;  2A0J A;  1A6J A;  4GQX A;  3LF6 A;  4M62 S;  1J6T A;  2FEW A;  3BJV A;  4M8Q C;  1XIZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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