4MHQA

Crystal structure of human primase catalytic subunit
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
419
structure length
400
Chain Sequence
METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAITRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Replication
molecule keywords DNA primase small subunit
publication title Crystal structure of human primase catalytic subunit
rcsb
source organism Homo sapiens
total genus 134
structure length 400
sequence length 419
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01896 DNA_primase_S DNA primase small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.920.30 Alpha Beta Alpha-Beta Complex DNA primase, PRIM domain DNA primase, PRIM domain 4mhqA00
2FAOA 4BPUA 5EXRA 4MHQA 4BPXA 1ZT2A 4MM2A 2FAQA 4LIMA 4LIKA 4LILA 4BPWA 4RR2A 2FARA
chains in the Genus database with same CATH superfamily
2FAOA 4BPUA 1V34A 5EXRA 4MHQA 4BPXA 2ATZA 1V33A 1ZT2A 2FAQA 4LIMA 4MM2A 4BPWA 4LIKA 4LILA 1G71A 4RR2A 2FARA
chains in the Genus database with same CATH topology
2FAOA 4BPUA 1V34A 5EXRA 4MHQA 4BPXA 1V33A 1ZT2A 2FAQA 4LIMA 4MM2A 4BPWA 4LIKA 4LILA 1G71A 4RR2A 2FARA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FAO A;  4BPU A;  5EXR A;  4MHQ A;  4BPX A;  1ZT2 A;  4MM2 A;  2FAQ A;  4LIM A;  4LIK A;  4LIL A;  4BPW A;  4RR2 A;  2FAR A; 
#chains in the Genus database with same CATH topology
 2FAO A;  4BPU A;  1V34 A;  5EXR A;  4MHQ A;  4BPX A;  2ATZ A;  1V33 A;  1ZT2 A;  2FAQ A;  4LIM A;  4MM2 A;  4BPW A;  4LIK A;  4LIL A;  1G71 A;  4RR2 A;  2FAR A; 
#chains in the Genus database with same CATH homology
 2FAO A;  4BPU A;  1V34 A;  5EXR A;  4MHQ A;  4BPX A;  1V33 A;  1ZT2 A;  2FAQ A;  4LIM A;  4MM2 A;  4BPW A;  4LIK A;  4LIL A;  1G71 A;  4RR2 A;  2FAR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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