4RR2B

Crystal structure of human primase
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
224
structure length
213
Chain Sequence
FYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA primase small subunit
publication title Crystal structure of the human primase.
pubmed doi rcsb
source organism Homo sapiens
total genus 67
structure length 213
sequence length 224
chains with identical sequence D
ec nomenclature ec 2.7.7.-:
pdb deposition date 2014-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04104 DNA_primase_lrg Eukaryotic and archaeal DNA primase, large subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.80 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Transcription Elongation Factor S-II; Chain A 4rr2B00
4RR2B 4BPXB 4BPWB 4BPUB
chains in the Genus database with same CATH superfamily
4MCSA 3PLFB 3VROA 4BPUB 3HPHE 4OC3A 1DE4C 4GPLB 1WJTA 3BUOB 3OAKA 3BUXB 3S9LA 3NFQA 2VKZG 3BHXA 4P4IA 2PVWA 3BUNB 2JBJA 5ELYA 3BI1A 4BTFA 4BPXB 2OR4A 4JZ0A 3VGOA 2CIJA 3OB2B 3KASA 3SJGA 2UV8G 3OB1B 4NGMA 3RBUA 3BI0A 2DLAA 2XEJA 2C6GA 3S9MA 5AXIA 2JBKA 4OC2A 2XPOA 3BXMA 3FEEA 2XPPA 4NGTA 2XEGA 4A4BA 3PFVA 5F13A 1EO0A 3OP0A 4P4DA 1Z9EA 4P4FA 2CBLA 4LQGA 4NGSA 1Z8LA 3VRPA 3F9KC 5HKWA 3HMJG 3FF3A 2XPNA 3PT1A 3VRQA 4BPWB 5HKZA 1YVHA 5J3XA 1CX8A 4OC4A 4OC0A 2Y1NA 4NGPA 2OOTA 3S9NA 3HPGG 4P4BA 4RR2B 4A4CA 4NGQA 3IWWA 5D29A 3D7FA 4P45A 5BY0A 3D7GA 2XEFA 4X3RA 3SJEA 3ZNIA 4NGRA 4P44A 4MCQA 5HKYA 4W9YA 4MCPA 3SJFA 4OC5A 2XPLA 2C6PA 4OC1A 4OMEA 1B47A 3FECA 3D7HA 3BUWB 3D7DA 1FBVA 2XEIA 2Y1MA 3VRNA 3VRRA 3SJXA 4MCRA 4JYWA 3U88C 2C6CA 5F09A 2B4JC 4NGNA 2PVVA 4P4JA 3O8ZA 2N3AB 3FEDA 4P4EA 3BUMB
chains in the Genus database with same CATH topology
2UV8G 4RR2B 2VKZG 5BY0A 3HMJG 2DLAA 3PT1A 4BPXB 4BPWB 5F13A 4BPUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RR2 B;  4BPX B;  4BPW B;  4BPU B; 
#chains in the Genus database with same CATH topology
 4MCS A;  3PLF B;  3VRO A;  4BPU B;  3HPH E;  4OC3 A;  1DE4 C;  4GPL B;  1WJT A;  3BUO B;  3OAK A;  3BUX B;  3S9L A;  3NFQ A;  2VKZ G;  3BHX A;  4P4I A;  2PVW A;  3BUN B;  2JBJ A;  5ELY A;  3BI1 A;  4BTF A;  4BPX B;  2OR4 A;  4JZ0 A;  3VGO A;  2CIJ A;  3OB2 B;  3KAS A;  3SJG A;  2UV8 G;  3OB1 B;  4NGM A;  3RBU A;  3BI0 A;  2DLA A;  2XEJ A;  2C6G A;  3S9M A;  5AXI A;  2JBK A;  4OC2 A;  2XPO A;  3BXM A;  3FEE A;  2XPP A;  4NGT A;  2XEG A;  4A4B A;  3PFV A;  5F13 A;  1EO0 A;  3OP0 A;  4P4D A;  1Z9E A;  4P4F A;  2CBL A;  4LQG A;  4NGS A;  1Z8L A;  3VRP A;  3F9K C;  5HKW A;  3HMJ G;  3FF3 A;  2XPN A;  3PT1 A;  3VRQ A;  4BPW B;  5HKZ A;  1YVH A;  5J3X A;  1CX8 A;  4OC4 A;  4OC0 A;  2Y1N A;  4NGP A;  2OOT A;  3S9N A;  3HPG G;  4P4B A;  4RR2 B;  4A4C A;  4NGQ A;  3IWW A;  5D29 A;  3D7F A;  4P45 A;  5BY0 A;  3D7G A;  2XEF A;  4X3R A;  3SJE A;  3ZNI A;  4NGR A;  4P44 A;  4MCQ A;  5HKY A;  4W9Y A;  4MCP A;  3SJF A;  4OC5 A;  2XPL A;  2C6P A;  4OC1 A;  4OME A;  1B47 A;  3FEC A;  3D7H A;  3BUW B;  3D7D A;  1FBV A;  2XEI A;  2Y1M A;  3VRN A;  3VRR A;  3SJX A;  4MCR A;  4JYW A;  3U88 C;  2C6C A;  5F09 A;  2B4J C;  4NGN A;  2PVV A;  4P4J A;  3O8Z A;  2N3A B;  3FED A;  4P4E A;  3BUM B; 
#chains in the Genus database with same CATH homology
 2UV8 G;  4RR2 B;  2VKZ G;  5BY0 A;  3HMJ G;  2DLA A;  3PT1 A;  4BPX B;  4BPW B;  5F13 A;  4BPU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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