4DEMF

Crystal structure of human fpps in complex with ys_04_70
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells.
pubmed doi rcsb
source organism Homo sapiens
total genus 138
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2012-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4demF00
2I19A 5A0IA 2Z52A 2ZY1A 1N20A 2E90A 4PVXF 2E8XA 3WEIA 1RQJA 4XQSF 1WY0A 1YJ4A 3W7FA 3ZL6A 1VG7A 2Q9ZA 2OPNA 3KRFB 1VG2A 3P41A 4GAXA 5B0MA 3WCAA 4LA6A 4XQRF 1WL3A 2ZCRA 3LEEA 3BNXA 4KVWA 5DGSF 5IL3A 3ZMCA 2Z7HA 3WCLA 5IL8A 2E8UA 4JYXA 3DYFA 4FP4A 5H9DA 4KVDA 1UBVA 3CP6A 4F6XA 5IMNA 5E8KA 1N23A 4RXEA 3P8LA 5ILIA 3NPKA 2E4OA 4N1ZF 3M01A 5B0JA 2ZCOA 5ERNA 1N1BA 1YHLA 1N1ZA 3SDUA 3OYRA 3KRAA 4FJQA 4NUAA 2H8OA 3LVSA 4P0VA 2E8WA 4LUUA 5JUZF 2RAHA 5B02A 4NKEA 3ICKA 4NG6A 2J5CA 4JXNA 3N45F 4JZBA 3LJIA 3N5HF 3ACWA 4NFJF 4LPHF 4MC8A 5ER8A 3ACYA 1V4JA 3RBMA 5DJRF 5IK6A 1JFGA 3SDRA 4LOBA 2ZEUA 3QQVA 4JZXA 2PS4A 3N6KF 3N1WF 5DHIA 3N49F 4OKZA 5IM1A 3ZOUA 5DGMF 5HN9A 3QKCA 2AELA 1N24A 1DGPA 1V4IA 4E9ZA 4EA0A 5B00A 1V4HA 2F7MF 3PH7A 3M0GA 4LA5A 4MC3A 4KKMA 3SDTA 3ICNA 4Q23A 3VJDA 5DJVF 1FPSA 2ZCQA 4KK2A 3ADZA 3VJAA 3N0FA 3TC1A 4GP1A 1VG3A 3KROA 4EA2A 5DW7A 1N22A 2J1PA 4UMJA 4KPDA 2Z7IA 4GP2A 3KRPB 2ONGA 4E9UA 4KQUA 4KQSA 1JFAA 5EROA 5EAUA 1VG4A 3WCCA 4DWGA 4KWDA 3WC9A 2Q58A 2ONHA 2Q80A 2AZJA 2DH4A 3WEGA 2F9KF 3ASXA 3VJ8A 3WSBA 4OKMA 3PKOA 1HM7A 3PDEA 3KRPA 3N46F 4RXCA 3EZ3A 5IVGA 3WJKA 3KRAB 3M9UA 4DWBA 5IK0A 5IKAA 4RNQA 1UBYA 2PS5A 1YYTA 3WCJA 2Q9YA 5DHKA 3G4DA 4LTZA 1V4KA 4OGUA 3WCGA 2AETA 3OACB 4LXWA 3WCDA 4MC0A 4QPFA 3VJBA 5E8LA 1WL2A 4H5DF 3IBAA 4H5EF 2J1OA 2AZKA 4EA1A 4LZ3A 3CC9A 5IKHA 3Q2ZA 4KVYA 1YHMA 5JV2F 3UCAA 3OACA 3WCHA 3WEJA 3N1VF 4RYPA 2Z50A 3M00A 2Z4YA 4N9UA 5IN8A 1HXCA 4LFGA 4WK5A 1RTRA 3DYGA 3PYAA 3LGKA 5IK9A 4JXYA 5ILZA 2QISA 3WJNA 4NFIF 3S4JA 2ZEVA 5ILDA 5AYPA 3LMDA 3WCEA 4K10A 2FTZA 3G4FA 3MAVA 3WE9A 3TFNA 4L2XF 3AQBB 3NPRA 4GA3A 1RQIA 2FORA 1YYQA 1YYSA 3KROB 3WCIA 3ACXA 1WKZA 5E8HA 3WEHA 5B03A 3LG5A 5ILJA 4P0WA 5JV0F 4KFAA 2F92F 3BNYA 1YQ7A 3LDWA 4KUXA 4JVJF 2F89F 1N21A 2VF6A 5ILYA 2OPMA 3Q1OA 2PS7A 5ILKA 4NFKF 5HN7A 3N5JF 4PVYF 1WL0A 3N3LF 4DEMF 2E93A 4DXJA 3APZA 3LGZB 4LLTA 5IMPA 4F62A 3LZ9A 3WCFA 5ILHA 5B0LA 1KIYA 5DIQF 4DZWA 3EFQA 4OMGA 2AZLA 4NKFA 3V66A 4XQTF 3ZCDA 2E92A 4LLSA 3VJCA 3N0GA 2E91A 1WL1A 4LZCA 2OGDA 1YV5A 1V4EA 3OABA 3WJOA 3B7LA 3NF2A 2Z4ZA 3PYBA 2Z4XA 2PS6A 5C05A 3EGTA 3MZVA 1YHKA 2F94F 3RYEA 5JA0F 3NRIA 4P0XA 5DZ2A 2EWGA 5DGNF 1HXGA 2O1OA 3V1VA 4KQ5A 1HX9A 3P8RA 3KRFA 1HM4A 4OMHA 3SDQA 4LTVA 5AFXA 2Z4VA 3KRCB 3VJEA 3AE0A 3S9VA 3TFVA 5KSXF 5B0IA 5A0KA 1DI1A 4LIXA 3ZMBA 3IPIA 5HN8A 4E1EA 3WCMA 3KBKA 2Z78A 1EZFA 5B01A 4F6VA 3KRCA 3WEKA 5IMIA 3LK5A 2OA6A 1UBXA 2PS8A 3VJ9A 1ZW5A 4LZ0A 2ZCSA 3WEFA 3V1XA 2F8CF 5HNAA 3M02A 3LOMA 4LFEA 2AEKA 1KIZA 4H5CF 2Z4WA 4LFVF 5EATA 3DYHA 3Q30A 3P5RA 1YYUA 4QXSF 4DI5A 5I1UA 3ICZA 3RMGA 1YYRA 3TFPA 4KVIA 1VG6A 5CG6A 5AHUB 2E8TA 3LLWA 5CG5A 4DHDA 5A0JA 5AELA 3Q2QA 1WMWA 3SAEA 1UBWA 5DJPF 4ZQ8A 1PS1A 3WSAA 3TS7A 3WCBA 2P1CA 3N3DA 2E8VA 5JV1F 4HD1A 3LSNA 3ID0A 4RXAA 4LPGF 3CKEA 5B0KA 3KB9A 2F8ZF 1HXAA 3ICMA 3AQCB 5ERMA 4RXDA 2E95A 3OABB 2E94A 3P5PA 3AQ0A 5EASA 4KPJA 3SDVA 3RYWA
chains in the Genus database with same CATH superfamily
2I19A 5A0IA 2Z52A 2ZY1A 1N20A 2E90A 4PVXF 2E8XA 3WEIA 1RQJA 4XQSF 1WY0A 1YJ4A 3W7FA 3ZL6A 1VG7A 2Q9ZA 2OPNA 3KRFB 1VG2A 3P41A 4GAXA 5B0MA 3WCAA 4LA6A 4XQRF 1WL3A 2ZCRA 3LEEA 3BNXA 4KVWA 5DGSF 5IL3A 3ZMCA 2Z7HA 3WCLA 5IL8A 2E8UA 4JYXA 3DYFA 4FP4A 5H9DA 4KVDA 1UBVA 3CP6A 4F6XA 5IMNA 5E8KA 1N23A 4RXEA 3P8LA 5ILIA 3NPKA 2E4OA 4N1ZF 3M01A 5B0JA 2ZCOA 5ERNA 1N1BA 1YHLA 1N1ZA 3SDUA 3OYRA 3KRAA 4FJQA 4NUAA 2H8OA 3LVSA 4P0VA 2E8WA 4LUUA 5JUZF 2RAHA 5B02A 4NKEA 3ICKA 4NG6A 2J5CA 4JXNA 3N45F 4JZBA 3LJIA 3N5HF 3ACWA 4NFJF 4LPHF 4MC8A 5ER8A 3ACYA 1V4JA 3RBMA 5DJRF 5IK6A 1JFGA 3SDRA 4LOBA 2ZEUA 3QQVA 4JZXA 2PS4A 3N6KF 3N1WF 5DHIA 3N49F 4OKZA 5IM1A 3ZOUA 5DGMF 5HN9A 3QKCA 2AELA 1N24A 1DGPA 1V4IA 4E9ZA 4EA0A 5B00A 1V4HA 2F7MF 3PH7A 3M0GA 4LA5A 4MC3A 4KKMA 3SDTA 3ICNA 4Q23A 3VJDA 5DJVF 1FPSA 2ZCQA 4KK2A 3ADZA 3VJAA 3N0FA 3TC1A 4GP1A 1VG3A 3KROA 4EA2A 5DW7A 1N22A 2J1PA 4UMJA 4KPDA 2Z7IA 4GP2A 3KRPB 2ONGA 4E9UA 4KQUA 4KQSA 1JFAA 5EROA 5EAUA 1VG4A 3WCCA 4DWGA 4KWDA 3WC9A 2Q58A 2ONHA 2Q80A 2AZJA 2DH4A 3WEGA 2F9KF 3ASXA 3VJ8A 3WSBA 4OKMA 3PKOA 1HM7A 3PDEA 3KRPA 3N46F 4RXCA 3EZ3A 5IVGA 3WJKA 3KRAB 3M9UA 4DWBA 5IK0A 5IKAA 4RNQA 1UBYA 2PS5A 1YYTA 3WCJA 2Q9YA 5DHKA 3G4DA 4LTZA 1V4KA 4OGUA 3WCGA 2AETA 3OACB 4LXWA 3WCDA 4MC0A 4QPFA 3VJBA 5E8LA 1WL2A 4H5DF 3IBAA 4H5EF 2J1OA 2AZKA 4EA1A 4LZ3A 3CC9A 5IKHA 3Q2ZA 4KVYA 1YHMA 5JV2F 3UCAA 3OACA 3WCHA 3WEJA 3N1VF 4RYPA 2Z50A 3M00A 2Z4YA 4N9UA 5IN8A 1HXCA 4LFGA 4WK5A 1RTRA 3DYGA 3PYAA 3LGKA 5IK9A 4JXYA 5ILZA 2QISA 3WJNA 4NFIF 3S4JA 2ZEVA 5ILDA 5AYPA 3LMDA 3WCEA 4K10A 2FTZA 3G4FA 3MAVA 3WE9A 3TFNA 4L2XF 3AQBB 3NPRA 4GA3A 1RQIA 2FORA 1YYQA 1YYSA 3KROB 3WCIA 3ACXA 1WKZA 5E8HA 3WEHA 5B03A 3LG5A 5ILJA 4P0WA 5JV0F 4KFAA 2F92F 3BNYA 1YQ7A 3LDWA 4KUXA 4JVJF 2F89F 1N21A 2VF6A 5ILYA 2OPMA 3Q1OA 2PS7A 5ILKA 4NFKF 5HN7A 3N5JF 4PVYF 1WL0A 3N3LF 4DEMF 2E93A 4DXJA 3APZA 3LGZB 4LLTA 5IMPA 4F62A 3LZ9A 3WCFA 5ILHA 5B0LA 1KIYA 5DIQF 4DZWA 3EFQA 4OMGA 2AZLA 4NKFA 3V66A 4XQTF 3ZCDA 2E92A 4LLSA 3VJCA 3N0GA 2E91A 1WL1A 4LZCA 2OGDA 1YV5A 1V4EA 3OABA 3WJOA 3B7LA 3NF2A 2Z4ZA 3PYBA 2Z4XA 2PS6A 5C05A 3EGTA 3MZVA 1YHKA 2F94F 3RYEA 5JA0F 3NRIA 4P0XA 5DZ2A 2EWGA 5DGNF 1HXGA 2O1OA 3V1VA 4KQ5A 1HX9A 3P8RA 3KRFA 1HM4A 4OMHA 3SDQA 4LTVA 5AFXA 2Z4VA 3KRCB 3VJEA 3AE0A 3S9VA 3TFVA 5KSXF 5B0IA 5A0KA 1DI1A 4LIXA 3ZMBA 3IPIA 5HN8A 4E1EA 3WCMA 3KBKA 2Z78A 1EZFA 5B01A 4F6VA 3KRCA 3WEKA 5IMIA 3LK5A 2OA6A 1UBXA 2PS8A 3VJ9A 1ZW5A 4LZ0A 2ZCSA 3WEFA 3V1XA 2F8CF 5HNAA 3M02A 3LOMA 4LFEA 2AEKA 1KIZA 4H5CF 2Z4WA 4LFVF 5EATA 3DYHA 3Q30A 3P5RA 1YYUA 4QXSF 4DI5A 5I1UA 3ICZA 3RMGA 1YYRA 3TFPA 4KVIA 1VG6A 5CG6A 5AHUB 2E8TA 3LLWA 5CG5A 4DHDA 5A0JA 5AELA 3Q2QA 1WMWA 3SAEA 1UBWA 5DJPF 4ZQ8A 1PS1A 3WSAA 3TS7A 3WCBA 2P1CA 3N3DA 2E8VA 5JV1F 4HD1A 3LSNA 3ID0A 4RXAA 4LPGF 3CKEA 5B0KA 3KB9A 2F8ZF 1HXAA 3ICMA 3AQCB 5ERMA 4RXDA 2E95A 3OABB 2E94A 3P5PA 3AQ0A 5EASA 4KPJA 3SDVA 3RYWA
chains in the Genus database with same CATH topology
2I19A 5A0IA 2Z52A 2ZY1A 1N20A 2E90A 4PVXF 2E8XA 3WEIA 1RQJA 4XQSF 1WY0A 1YJ4A 3W7FA 3ZL6A 1VG7A 2Q9ZA 2OPNA 3KRFB 1VG2A 3P41A 4GAXA 5B0MA 3WCAA 4LA6A 4XQRF 1WL3A 2ZCRA 3LEEA 3BNXA 4KVWA 5DGSF 5IL3A 3ZMCA 2Z7HA 3WCLA 5IL8A 2E8UA 4JYXA 3DYFA 4FP4A 5H9DA 4KVDA 1UBVA 3CP6A 4F6XA 5IMNA 5E8KA 1N23A 4RXEA 3P8LA 5ILIA 3NPKA 2E4OA 4N1ZF 3M01A 5B0JA 2ZCOA 5ERNA 1N1BA 1YHLA 1N1ZA 3SDUA 3OYRA 3KRAA 4FJQA 4NUAA 2H8OA 3LVSA 4P0VA 2E8WA 4LUUA 5JUZF 2RAHA 5B02A 4NKEA 3ICKA 4NG6A 2J5CA 4JXNA 3N45F 4JZBA 3LJIA 3N5HF 3ACWA 4NFJF 4LPHF 4MC8A 5ER8A 3ACYA 1V4JA 3RBMA 5DJRF 5IK6A 1JFGA 3SDRA 4LOBA 2ZEUA 3QQVA 4JZXA 2PS4A 3N6KF 3N1WF 5DHIA 3N49F 4OKZA 5IM1A 3ZOUA 5DGMF 5HN9A 3QKCA 2AELA 1N24A 1DGPA 1V4IA 4E9ZA 4EA0A 5B00A 1V4HA 2F7MF 3PH7A 3M0GA 4LA5A 4MC3A 4KKMA 3SDTA 3ICNA 4Q23A 3VJDA 5DJVF 1FPSA 2ZCQA 4KK2A 3ADZA 3VJAA 3N0FA 3TC1A 4GP1A 1VG3A 3KROA 4EA2A 5DW7A 1N22A 2J1PA 4UMJA 4KPDA 2Z7IA 4GP2A 3KRPB 2ONGA 4E9UA 4KQUA 4KQSA 1JFAA 5EROA 5EAUA 1VG4A 3WCCA 4DWGA 4KWDA 3WC9A 2Q58A 2ONHA 2Q80A 2AZJA 2DH4A 3WEGA 2F9KF 3ASXA 3VJ8A 3WSBA 4OKMA 3PKOA 1HM7A 3PDEA 3KRPA 3N46F 4RXCA 3EZ3A 5IVGA 3WJKA 3KRAB 3M9UA 4DWBA 5IK0A 5IKAA 4RNQA 1UBYA 2PS5A 1YYTA 3WCJA 2Q9YA 5DHKA 3G4DA 4LTZA 1V4KA 4OGUA 3WCGA 2AETA 3OACB 4LXWA 3WCDA 4MC0A 4QPFA 3VJBA 5E8LA 1WL2A 4H5DF 3IBAA 4H5EF 2J1OA 2AZKA 4EA1A 4LZ3A 3CC9A 5IKHA 3Q2ZA 4KVYA 1YHMA 5JV2F 3UCAA 3OACA 3WCHA 3WEJA 3N1VF 4RYPA 2Z50A 3M00A 2Z4YA 4N9UA 5IN8A 1HXCA 4LFGA 4WK5A 1RTRA 3DYGA 3PYAA 3LGKA 5IK9A 4JXYA 5ILZA 2QISA 3WJNA 4NFIF 3S4JA 2ZEVA 5ILDA 5AYPA 3LMDA 3WCEA 4K10A 2FTZA 3G4FA 3MAVA 3WE9A 3TFNA 4L2XF 3AQBB 3NPRA 4GA3A 1RQIA 2FORA 1YYQA 1YYSA 3KROB 3WCIA 3ACXA 1WKZA 5E8HA 3WEHA 5B03A 3LG5A 5ILJA 4P0WA 5JV0F 4KFAA 2F92F 3BNYA 1YQ7A 3LDWA 4KUXA 4JVJF 2F89F 1N21A 2VF6A 5ILYA 2OPMA 3Q1OA 2PS7A 5ILKA 4NFKF 5HN7A 3N5JF 4PVYF 1WL0A 3N3LF 4DEMF 2E93A 4DXJA 3APZA 3LGZB 4LLTA 5IMPA 4F62A 3LZ9A 3WCFA 5ILHA 5B0LA 1KIYA 5DIQF 4DZWA 3EFQA 4OMGA 2AZLA 4NKFA 3V66A 4XQTF 3ZCDA 2E92A 4LLSA 3VJCA 3N0GA 2E91A 1WL1A 4LZCA 2OGDA 1YV5A 1V4EA 3OABA 3WJOA 3B7LA 3NF2A 2Z4ZA 3PYBA 2Z4XA 2PS6A 5C05A 3EGTA 3MZVA 1YHKA 2F94F 3RYEA 5JA0F 3NRIA 4P0XA 5DZ2A 2EWGA 5DGNF 1HXGA 2O1OA 3V1VA 4KQ5A 1HX9A 3P8RA 3KRFA 1HM4A 4OMHA 3SDQA 4LTVA 5AFXA 2Z4VA 3KRCB 3VJEA 3AE0A 3S9VA 3TFVA 5KSXF 5B0IA 5A0KA 1DI1A 4LIXA 3ZMBA 3IPIA 5HN8A 4E1EA 3WCMA 3KBKA 2Z78A 1EZFA 5B01A 4F6VA 3KRCA 3WEKA 5IMIA 3LK5A 2OA6A 1UBXA 2PS8A 3VJ9A 1ZW5A 4LZ0A 2ZCSA 3WEFA 3V1XA 2F8CF 5HNAA 3M02A 3LOMA 4LFEA 2AEKA 1KIZA 4H5CF 2Z4WA 4LFVF 5EATA 3DYHA 3Q30A 3P5RA 1YYUA 4QXSF 4DI5A 5I1UA 3ICZA 3RMGA 1YYRA 3TFPA 4KVIA 1VG6A 5CG6A 5AHUB 2E8TA 3LLWA 5CG5A 4DHDA 5A0JA 5AELA 3Q2QA 1WMWA 3SAEA 1UBWA 5DJPF 4ZQ8A 1PS1A 3WSAA 3TS7A 3WCBA 2P1CA 3N3DA 2E8VA 5JV1F 4HD1A 3LSNA 3ID0A 4RXAA 4LPGF 3CKEA 5B0KA 3KB9A 2F8ZF 1HXAA 3ICMA 3AQCB 5ERMA 4RXDA 2E95A 3OABB 2E94A 3P5PA 3AQ0A 5EASA 4KPJA 3SDVA 3RYWA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2I19 A;  5A0I A;  2Z52 A;  2ZY1 A;  1N20 A;  2E90 A;  4PVX F;  2E8X A;  3WEI A;  1RQJ A;  4XQS F;  1WY0 A;  1YJ4 A;  3W7F A;  3ZL6 A;  1VG7 A;  2Q9Z A;  2OPN A;  3KRF B;  1VG2 A;  3P41 A;  4GAX A;  5B0M A;  3WCA A;  4LA6 A;  4XQR F;  1WL3 A;  2ZCR A;  3LEE A;  3BNX A;  4KVW A;  5DGS F;  5IL3 A;  3ZMC A;  2Z7H A;  3WCL A;  5IL8 A;  2E8U A;  4JYX A;  3DYF A;  4FP4 A;  5H9D A;  4KVD A;  1UBV A;  3CP6 A;  4F6X A;  5IMN A;  5E8K A;  1N23 A;  4RXE A;  3P8L A;  5ILI A;  3NPK A;  2E4O A;  4N1Z F;  3M01 A;  5B0J A;  2ZCO A;  5ERN A;  1N1B A;  1YHL A;  1N1Z A;  3SDU A;  3OYR A;  3KRA A;  4FJQ A;  4NUA A;  2H8O A;  3LVS A;  4P0V A;  2E8W A;  4LUU A;  5JUZ F;  2RAH A;  5B02 A;  4NKE A;  3ICK A;  4NG6 A;  2J5C A;  4JXN A;  3N45 F;  4JZB A;  3LJI A;  3N5H F;  3ACW A;  4NFJ F;  4LPH F;  4MC8 A;  5ER8 A;  3ACY A;  1V4J A;  3RBM A;  5DJR F;  5IK6 A;  1JFG A;  3SDR A;  4LOB A;  2ZEU A;  3QQV A;  4JZX A;  2PS4 A;  3N6K F;  3N1W F;  5DHI A;  3N49 F;  4OKZ A;  5IM1 A;  3ZOU A;  5DGM F;  5HN9 A;  3QKC A;  2AEL A;  1N24 A;  1DGP A;  1V4I A;  4E9Z A;  4EA0 A;  5B00 A;  1V4H A;  2F7M F;  3PH7 A;  3M0G A;  4LA5 A;  4MC3 A;  4KKM A;  3SDT A;  3ICN A;  4Q23 A;  3VJD A;  5DJV F;  1FPS A;  2ZCQ A;  4KK2 A;  3ADZ A;  3VJA A;  3N0F A;  3TC1 A;  4GP1 A;  1VG3 A;  3KRO A;  4EA2 A;  5DW7 A;  1N22 A;  2J1P A;  4UMJ A;  4KPD A;  2Z7I A;  4GP2 A;  3KRP B;  2ONG A;  4E9U A;  4KQU A;  4KQS A;  1JFA A;  5ERO A;  5EAU A;  1VG4 A;  3WCC A;  4DWG A;  4KWD A;  3WC9 A;  2Q58 A;  2ONH A;  2Q80 A;  2AZJ A;  2DH4 A;  3WEG A;  2F9K F;  3ASX A;  3VJ8 A;  3WSB A;  4OKM A;  3PKO A;  1HM7 A;  3PDE A;  3KRP A;  3N46 F;  4RXC A;  3EZ3 A;  5IVG A;  3WJK A;  3KRA B;  3M9U A;  4DWB A;  5IK0 A;  5IKA A;  4RNQ A;  1UBY A;  2PS5 A;  1YYT A;  3WCJ A;  2Q9Y A;  5DHK A;  3G4D A;  4LTZ A;  1V4K A;  4OGU A;  3WCG A;  2AET A;  3OAC B;  4LXW A;  3WCD A;  4MC0 A;  4QPF A;  3VJB A;  5E8L A;  1WL2 A;  4H5D F;  3IBA A;  4H5E F;  2J1O A;  2AZK A;  4EA1 A;  4LZ3 A;  3CC9 A;  5IKH A;  3Q2Z A;  4KVY A;  1YHM A;  5JV2 F;  3UCA A;  3OAC A;  3WCH A;  3WEJ A;  3N1V F;  4RYP A;  2Z50 A;  3M00 A;  2Z4Y A;  4N9U A;  5IN8 A;  1HXC A;  4LFG A;  4WK5 A;  1RTR A;  3DYG A;  3PYA A;  3LGK A;  5IK9 A;  4JXY A;  5ILZ A;  2QIS A;  3WJN A;  4NFI F;  3S4J A;  2ZEV A;  5ILD A;  5AYP A;  3LMD A;  3WCE A;  4K10 A;  2FTZ A;  3G4F A;  3MAV A;  3WE9 A;  3TFN A;  4L2X F;  3AQB B;  3NPR A;  4GA3 A;  1RQI A;  2FOR A;  1YYQ A;  1YYS A;  3KRO B;  3WCI A;  3ACX A;  1WKZ A;  5E8H A;  3WEH A;  5B03 A;  3LG5 A;  5ILJ A;  4P0W A;  5JV0 F;  4KFA A;  2F92 F;  3BNY A;  1YQ7 A;  3LDW A;  4KUX A;  4JVJ F;  2F89 F;  1N21 A;  2VF6 A;  5ILY A;  2OPM A;  3Q1O A;  2PS7 A;  5ILK A;  4NFK F;  5HN7 A;  3N5J F;  4PVY F;  1WL0 A;  3N3L F;  4DEM F;  2E93 A;  4DXJ A;  3APZ A;  3LGZ B;  4LLT A;  5IMP A;  4F62 A;  3LZ9 A;  3WCF A;  5ILH A;  5B0L A;  1KIY A;  5DIQ F;  4DZW A;  3EFQ A;  4OMG A;  2AZL A;  4NKF A;  3V66 A;  4XQT F;  3ZCD A;  2E92 A;  4LLS A;  3VJC A;  3N0G A;  2E91 A;  1WL1 A;  4LZC A;  2OGD A;  1YV5 A;  1V4E A;  3OAB A;  3WJO A;  3B7L A;  3NF2 A;  2Z4Z A;  3PYB A;  2Z4X A;  2PS6 A;  5C05 A;  3EGT A;  3MZV A;  1YHK A;  2F94 F;  3RYE A;  5JA0 F;  3NRI A;  4P0X A;  5DZ2 A;  2EWG A;  5DGN F;  1HXG A;  2O1O A;  3V1V A;  4KQ5 A;  1HX9 A;  3P8R A;  3KRF A;  1HM4 A;  4OMH A;  3SDQ A;  4LTV A;  5AFX A;  2Z4V A;  3KRC B;  3VJE A;  3AE0 A;  3S9V A;  3TFV A;  5KSX F;  5B0I A;  5A0K A;  1DI1 A;  4LIX A;  3ZMB A;  3IPI A;  5HN8 A;  4E1E A;  3WCM A;  3KBK A;  2Z78 A;  1EZF A;  5B01 A;  4F6V A;  3KRC A;  3WEK A;  5IMI A;  3LK5 A;  2OA6 A;  1UBX A;  2PS8 A;  3VJ9 A;  1ZW5 A;  4LZ0 A;  2ZCS A;  3WEF A;  3V1X A;  2F8C F;  5HNA A;  3M02 A;  3LOM A;  4LFE A;  2AEK A;  1KIZ A;  4H5C F;  2Z4W A;  4LFV F;  5EAT A;  3DYH A;  3Q30 A;  3P5R A;  1YYU A;  4QXS F;  4DI5 A;  5I1U A;  3ICZ A;  3RMG A;  1YYR A;  3TFP A;  4KVI A;  1VG6 A;  5CG6 A;  5AHU B;  2E8T A;  3LLW A;  5CG5 A;  4DHD A;  5A0J A;  5AEL A;  3Q2Q A;  1WMW A;  3SAE A;  1UBW A;  5DJP F;  4ZQ8 A;  1PS1 A;  3WSA A;  3TS7 A;  3WCB A;  2P1C A;  3N3D A;  2E8V A;  5JV1 F;  4HD1 A;  3LSN A;  3ID0 A;  4RXA A;  4LPG F;  3CKE A;  5B0K A;  3KB9 A;  2F8Z F;  1HXA A;  3ICM A;  3AQC B;  5ERM A;  4RXD A;  2E95 A;  3OAB B;  2E94 A;  3P5P A;  3AQ0 A;  5EAS A;  4KPJ A;  3SDV A;  3RYW A; 
#chains in the Genus database with same CATH topology
 2I19 A;  5A0I A;  2Z52 A;  2ZY1 A;  1N20 A;  2E90 A;  4PVX F;  2E8X A;  3WEI A;  1RQJ A;  4XQS F;  1WY0 A;  1YJ4 A;  3W7F A;  3ZL6 A;  1VG7 A;  2Q9Z A;  2OPN A;  3KRF B;  1VG2 A;  3P41 A;  4GAX A;  5B0M A;  3WCA A;  4LA6 A;  4XQR F;  1WL3 A;  2ZCR A;  3LEE A;  3BNX A;  4KVW A;  5DGS F;  5IL3 A;  3ZMC A;  2Z7H A;  3WCL A;  5IL8 A;  2E8U A;  4JYX A;  3DYF A;  4FP4 A;  5H9D A;  4KVD A;  1UBV A;  3CP6 A;  4F6X A;  5IMN A;  5E8K A;  1N23 A;  4RXE A;  3P8L A;  5ILI A;  3NPK A;  2E4O A;  4N1Z F;  3M01 A;  5B0J A;  2ZCO A;  5ERN A;  1N1B A;  1YHL A;  1N1Z A;  3SDU A;  3OYR A;  3KRA A;  4FJQ A;  4NUA A;  2H8O A;  3LVS A;  4P0V A;  2E8W A;  4LUU A;  5JUZ F;  2RAH A;  5B02 A;  4NKE A;  3ICK A;  4NG6 A;  2J5C A;  4JXN A;  3N45 F;  4JZB A;  3LJI A;  3N5H F;  3ACW A;  4NFJ F;  4LPH F;  4MC8 A;  5ER8 A;  3ACY A;  1V4J A;  3RBM A;  5DJR F;  5IK6 A;  1JFG A;  3SDR A;  4LOB A;  2ZEU A;  3QQV A;  4JZX A;  2PS4 A;  3N6K F;  3N1W F;  5DHI A;  3N49 F;  4OKZ A;  5IM1 A;  3ZOU A;  5DGM F;  5HN9 A;  3QKC A;  2AEL A;  1N24 A;  1DGP A;  1V4I A;  4E9Z A;  4EA0 A;  5B00 A;  1V4H A;  2F7M F;  3PH7 A;  3M0G A;  4LA5 A;  4MC3 A;  4KKM A;  3SDT A;  3ICN A;  4Q23 A;  3VJD A;  5DJV F;  1FPS A;  2ZCQ A;  4KK2 A;  3ADZ A;  3VJA A;  3N0F A;  3TC1 A;  4GP1 A;  1VG3 A;  3KRO A;  4EA2 A;  5DW7 A;  1N22 A;  2J1P A;  4UMJ A;  4KPD A;  2Z7I A;  4GP2 A;  3KRP B;  2ONG A;  4E9U A;  4KQU A;  4KQS A;  1JFA A;  5ERO A;  5EAU A;  1VG4 A;  3WCC A;  4DWG A;  4KWD A;  3WC9 A;  2Q58 A;  2ONH A;  2Q80 A;  2AZJ A;  2DH4 A;  3WEG A;  2F9K F;  3ASX A;  3VJ8 A;  3WSB A;  4OKM A;  3PKO A;  1HM7 A;  3PDE A;  3KRP A;  3N46 F;  4RXC A;  3EZ3 A;  5IVG A;  3WJK A;  3KRA B;  3M9U A;  4DWB A;  5IK0 A;  5IKA A;  4RNQ A;  1UBY A;  2PS5 A;  1YYT A;  3WCJ A;  2Q9Y A;  5DHK A;  3G4D A;  4LTZ A;  1V4K A;  4OGU A;  3WCG A;  2AET A;  3OAC B;  4LXW A;  3WCD A;  4MC0 A;  4QPF A;  3VJB A;  5E8L A;  1WL2 A;  4H5D F;  3IBA A;  4H5E F;  2J1O A;  2AZK A;  4EA1 A;  4LZ3 A;  3CC9 A;  5IKH A;  3Q2Z A;  4KVY A;  1YHM A;  5JV2 F;  3UCA A;  3OAC A;  3WCH A;  3WEJ A;  3N1V F;  4RYP A;  2Z50 A;  3M00 A;  2Z4Y A;  4N9U A;  5IN8 A;  1HXC A;  4LFG A;  4WK5 A;  1RTR A;  3DYG A;  3PYA A;  3LGK A;  5IK9 A;  4JXY A;  5ILZ A;  2QIS A;  3WJN A;  4NFI F;  3S4J A;  2ZEV A;  5ILD A;  5AYP A;  3LMD A;  3WCE A;  4K10 A;  2FTZ A;  3G4F A;  3MAV A;  3WE9 A;  3TFN A;  4L2X F;  3AQB B;  3NPR A;  4GA3 A;  1RQI A;  2FOR A;  1YYQ A;  1YYS A;  3KRO B;  3WCI A;  3ACX A;  1WKZ A;  5E8H A;  3WEH A;  5B03 A;  3LG5 A;  5ILJ A;  4P0W A;  5JV0 F;  4KFA A;  2F92 F;  3BNY A;  1YQ7 A;  3LDW A;  4KUX A;  4JVJ F;  2F89 F;  1N21 A;  2VF6 A;  5ILY A;  2OPM A;  3Q1O A;  2PS7 A;  5ILK A;  4NFK F;  5HN7 A;  3N5J F;  4PVY F;  1WL0 A;  3N3L F;  4DEM F;  2E93 A;  4DXJ A;  3APZ A;  3LGZ B;  4LLT A;  5IMP A;  4F62 A;  3LZ9 A;  3WCF A;  5ILH A;  5B0L A;  1KIY A;  5DIQ F;  4DZW A;  3EFQ A;  4OMG A;  2AZL A;  4NKF A;  3V66 A;  4XQT F;  3ZCD A;  2E92 A;  4LLS A;  3VJC A;  3N0G A;  2E91 A;  1WL1 A;  4LZC A;  2OGD A;  1YV5 A;  1V4E A;  3OAB A;  3WJO A;  3B7L A;  3NF2 A;  2Z4Z A;  3PYB A;  2Z4X A;  2PS6 A;  5C05 A;  3EGT A;  3MZV A;  1YHK A;  2F94 F;  3RYE A;  5JA0 F;  3NRI A;  4P0X A;  5DZ2 A;  2EWG A;  5DGN F;  1HXG A;  2O1O A;  3V1V A;  4KQ5 A;  1HX9 A;  3P8R A;  3KRF A;  1HM4 A;  4OMH A;  3SDQ A;  4LTV A;  5AFX A;  2Z4V A;  3KRC B;  3VJE A;  3AE0 A;  3S9V A;  3TFV A;  5KSX F;  5B0I A;  5A0K A;  1DI1 A;  4LIX A;  3ZMB A;  3IPI A;  5HN8 A;  4E1E A;  3WCM A;  3KBK A;  2Z78 A;  1EZF A;  5B01 A;  4F6V A;  3KRC A;  3WEK A;  5IMI A;  3LK5 A;  2OA6 A;  1UBX A;  2PS8 A;  3VJ9 A;  1ZW5 A;  4LZ0 A;  2ZCS A;  3WEF A;  3V1X A;  2F8C F;  5HNA A;  3M02 A;  3LOM A;  4LFE A;  2AEK A;  1KIZ A;  4H5C F;  2Z4W A;  4LFV F;  5EAT A;  3DYH A;  3Q30 A;  3P5R A;  1YYU A;  4QXS F;  4DI5 A;  5I1U A;  3ICZ A;  3RMG A;  1YYR A;  3TFP A;  4KVI A;  1VG6 A;  5CG6 A;  5AHU B;  2E8T A;  3LLW A;  5CG5 A;  4DHD A;  5A0J A;  5AEL A;  3Q2Q A;  1WMW A;  3SAE A;  1UBW A;  5DJP F;  4ZQ8 A;  1PS1 A;  3WSA A;  3TS7 A;  3WCB A;  2P1C A;  3N3D A;  2E8V A;  5JV1 F;  4HD1 A;  3LSN A;  3ID0 A;  4RXA A;  4LPG F;  3CKE A;  5B0K A;  3KB9 A;  2F8Z F;  1HXA A;  3ICM A;  3AQC B;  5ERM A;  4RXD A;  2E95 A;  3OAB B;  2E94 A;  3P5P A;  3AQ0 A;  5EAS A;  4KPJ A;  3SDV A;  3RYW A; 
#chains in the Genus database with same CATH homology
 2I19 A;  5A0I A;  2Z52 A;  2ZY1 A;  1N20 A;  2E90 A;  4PVX F;  2E8X A;  3WEI A;  1RQJ A;  4XQS F;  1WY0 A;  1YJ4 A;  3W7F A;  3ZL6 A;  1VG7 A;  2Q9Z A;  2OPN A;  3KRF B;  1VG2 A;  3P41 A;  4GAX A;  5B0M A;  3WCA A;  4LA6 A;  4XQR F;  1WL3 A;  2ZCR A;  3LEE A;  3BNX A;  4KVW A;  5DGS F;  5IL3 A;  3ZMC A;  2Z7H A;  3WCL A;  5IL8 A;  2E8U A;  4JYX A;  3DYF A;  4FP4 A;  5H9D A;  4KVD A;  1UBV A;  3CP6 A;  4F6X A;  5IMN A;  5E8K A;  1N23 A;  4RXE A;  3P8L A;  5ILI A;  3NPK A;  2E4O A;  4N1Z F;  3M01 A;  5B0J A;  2ZCO A;  5ERN A;  1N1B A;  1YHL A;  1N1Z A;  3SDU A;  3OYR A;  3KRA A;  4FJQ A;  4NUA A;  2H8O A;  3LVS A;  4P0V A;  2E8W A;  4LUU A;  5JUZ F;  2RAH A;  5B02 A;  4NKE A;  3ICK A;  4NG6 A;  2J5C A;  4JXN A;  3N45 F;  4JZB A;  3LJI A;  3N5H F;  3ACW A;  4NFJ F;  4LPH F;  4MC8 A;  5ER8 A;  3ACY A;  1V4J A;  3RBM A;  5DJR F;  5IK6 A;  1JFG A;  3SDR A;  4LOB A;  2ZEU A;  3QQV A;  4JZX A;  2PS4 A;  3N6K F;  3N1W F;  5DHI A;  3N49 F;  4OKZ A;  5IM1 A;  3ZOU A;  5DGM F;  5HN9 A;  3QKC A;  2AEL A;  1N24 A;  1DGP A;  1V4I A;  4E9Z A;  4EA0 A;  5B00 A;  1V4H A;  2F7M F;  3PH7 A;  3M0G A;  4LA5 A;  4MC3 A;  4KKM A;  3SDT A;  3ICN A;  4Q23 A;  3VJD A;  5DJV F;  1FPS A;  2ZCQ A;  4KK2 A;  3ADZ A;  3VJA A;  3N0F A;  3TC1 A;  4GP1 A;  1VG3 A;  3KRO A;  4EA2 A;  5DW7 A;  1N22 A;  2J1P A;  4UMJ A;  4KPD A;  2Z7I A;  4GP2 A;  3KRP B;  2ONG A;  4E9U A;  4KQU A;  4KQS A;  1JFA A;  5ERO A;  5EAU A;  1VG4 A;  3WCC A;  4DWG A;  4KWD A;  3WC9 A;  2Q58 A;  2ONH A;  2Q80 A;  2AZJ A;  2DH4 A;  3WEG A;  2F9K F;  3ASX A;  3VJ8 A;  3WSB A;  4OKM A;  3PKO A;  1HM7 A;  3PDE A;  3KRP A;  3N46 F;  4RXC A;  3EZ3 A;  5IVG A;  3WJK A;  3KRA B;  3M9U A;  4DWB A;  5IK0 A;  5IKA A;  4RNQ A;  1UBY A;  2PS5 A;  1YYT A;  3WCJ A;  2Q9Y A;  5DHK A;  3G4D A;  4LTZ A;  1V4K A;  4OGU A;  3WCG A;  2AET A;  3OAC B;  4LXW A;  3WCD A;  4MC0 A;  4QPF A;  3VJB A;  5E8L A;  1WL2 A;  4H5D F;  3IBA A;  4H5E F;  2J1O A;  2AZK A;  4EA1 A;  4LZ3 A;  3CC9 A;  5IKH A;  3Q2Z A;  4KVY A;  1YHM A;  5JV2 F;  3UCA A;  3OAC A;  3WCH A;  3WEJ A;  3N1V F;  4RYP A;  2Z50 A;  3M00 A;  2Z4Y A;  4N9U A;  5IN8 A;  1HXC A;  4LFG A;  4WK5 A;  1RTR A;  3DYG A;  3PYA A;  3LGK A;  5IK9 A;  4JXY A;  5ILZ A;  2QIS A;  3WJN A;  4NFI F;  3S4J A;  2ZEV A;  5ILD A;  5AYP A;  3LMD A;  3WCE A;  4K10 A;  2FTZ A;  3G4F A;  3MAV A;  3WE9 A;  3TFN A;  4L2X F;  3AQB B;  3NPR A;  4GA3 A;  1RQI A;  2FOR A;  1YYQ A;  1YYS A;  3KRO B;  3WCI A;  3ACX A;  1WKZ A;  5E8H A;  3WEH A;  5B03 A;  3LG5 A;  5ILJ A;  4P0W A;  5JV0 F;  4KFA A;  2F92 F;  3BNY A;  1YQ7 A;  3LDW A;  4KUX A;  4JVJ F;  2F89 F;  1N21 A;  2VF6 A;  5ILY A;  2OPM A;  3Q1O A;  2PS7 A;  5ILK A;  4NFK F;  5HN7 A;  3N5J F;  4PVY F;  1WL0 A;  3N3L F;  4DEM F;  2E93 A;  4DXJ A;  3APZ A;  3LGZ B;  4LLT A;  5IMP A;  4F62 A;  3LZ9 A;  3WCF A;  5ILH A;  5B0L A;  1KIY A;  5DIQ F;  4DZW A;  3EFQ A;  4OMG A;  2AZL A;  4NKF A;  3V66 A;  4XQT F;  3ZCD A;  2E92 A;  4LLS A;  3VJC A;  3N0G A;  2E91 A;  1WL1 A;  4LZC A;  2OGD A;  1YV5 A;  1V4E A;  3OAB A;  3WJO A;  3B7L A;  3NF2 A;  2Z4Z A;  3PYB A;  2Z4X A;  2PS6 A;  5C05 A;  3EGT A;  3MZV A;  1YHK A;  2F94 F;  3RYE A;  5JA0 F;  3NRI A;  4P0X A;  5DZ2 A;  2EWG A;  5DGN F;  1HXG A;  2O1O A;  3V1V A;  4KQ5 A;  1HX9 A;  3P8R A;  3KRF A;  1HM4 A;  4OMH A;  3SDQ A;  4LTV A;  5AFX A;  2Z4V A;  3KRC B;  3VJE A;  3AE0 A;  3S9V A;  3TFV A;  5KSX F;  5B0I A;  5A0K A;  1DI1 A;  4LIX A;  3ZMB A;  3IPI A;  5HN8 A;  4E1E A;  3WCM A;  3KBK A;  2Z78 A;  1EZF A;  5B01 A;  4F6V A;  3KRC A;  3WEK A;  5IMI A;  3LK5 A;  2OA6 A;  1UBX A;  2PS8 A;  3VJ9 A;  1ZW5 A;  4LZ0 A;  2ZCS A;  3WEF A;  3V1X A;  2F8C F;  5HNA A;  3M02 A;  3LOM A;  4LFE A;  2AEK A;  1KIZ A;  4H5C F;  2Z4W A;  4LFV F;  5EAT A;  3DYH A;  3Q30 A;  3P5R A;  1YYU A;  4QXS F;  4DI5 A;  5I1U A;  3ICZ A;  3RMG A;  1YYR A;  3TFP A;  4KVI A;  1VG6 A;  5CG6 A;  5AHU B;  2E8T A;  3LLW A;  5CG5 A;  4DHD A;  5A0J A;  5AEL A;  3Q2Q A;  1WMW A;  3SAE A;  1UBW A;  5DJP F;  4ZQ8 A;  1PS1 A;  3WSA A;  3TS7 A;  3WCB A;  2P1C A;  3N3D A;  2E8V A;  5JV1 F;  4HD1 A;  3LSN A;  3ID0 A;  4RXA A;  4LPG F;  3CKE A;  5B0K A;  3KB9 A;  2F8Z F;  1HXA A;  3ICM A;  3AQC B;  5ERM A;  4RXD A;  2E95 A;  3OAB B;  2E94 A;  3P5P A;  3AQ0 A;  5EAS A;  4KPJ A;  3SDV A;  3RYW A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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