1I4SA

Crystal structure of rnase iii endonuclease domain from aquifex aeolicus at 2.15 angstrom resolution
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
147
structure length
147
Chain Sequence
MKMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFIVDLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKINETIIGDVFEALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords RIBONUCLEASE III
publication title Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage.
pubmed doi rcsb
source organism Aquifex aeolicus
total genus 45
structure length 147
sequence length 147
chains with identical sequence B
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2001-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00636 Ribonuclease_3 Ribonuclease III domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1520.10 Mainly Alpha Orthogonal Bundle Ribonuclease iii, N-terminal Endonuclease Domain; Chain A Ribonuclease III domain 1i4sA00
1RC5A 3O2RB 1I4SA 4OOGC 3C4BA 3C4TA 2NUFA 4M30A 2EZ6A 2A11A 2EB1A 3N3WA 4OUNA 2NUGA 1YZ9A 3RV0A 1U61A 2NUEA 4M2ZA 2FFLA 1YYWA 2GSLA 1JFZA 1YYKA 2QVWA 3RV1A 1YYOA 3O2RA 1RC7A 1O0WA
chains in the Genus database with same CATH superfamily
1RC5A 3O2RB 1I4SA 4OOGC 3C4BA 3C4TA 1ZTDA 2NUFA 4M30A 2EZ6A 2A11A 2EB1A 3N3WA 4OUNA 2NUGA 1YZ9A 3RV0A 1U61A 2NUEA 4M2ZA 2FFLA 1YYWA 2GSLA 1JFZA 1YYKA 2QVWA 3RV1A 1YYOA 3O2RA 1RC7A 1O0WA
chains in the Genus database with same CATH topology
1RC5A 3O2RB 1I4SA 4OOGC 3C4BA 3C4TA 2NUFA 4M30A 2EZ6A 2A11A 2EB1A 3N3WA 4OUNA 2NUGA 1YZ9A 3RV0A 1U61A 2NUEA 4M2ZA 2FFLA 1YYWA 2GSLA 1JFZA 1YYKA 2QVWA 3RV1A 1YYOA 3O2RA 1RC7A 1O0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RC5 A;  3O2R B;  1I4S A;  4OOG C;  3C4B A;  3C4T A;  2NUF A;  4M30 A;  2EZ6 A;  2A11 A;  2EB1 A;  3N3W A;  4OUN A;  2NUG A;  1YZ9 A;  3RV0 A;  1U61 A;  2NUE A;  4M2Z A;  2FFL A;  1YYW A;  2GSL A;  1JFZ A;  1YYK A;  2QVW A;  3RV1 A;  1YYO A;  3O2R A;  1RC7 A;  1O0W A; 
#chains in the Genus database with same CATH topology
 1RC5 A;  3O2R B;  1I4S A;  4OOG C;  3C4B A;  3C4T A;  1ZTD A;  2NUF A;  4M30 A;  2EZ6 A;  2A11 A;  2EB1 A;  3N3W A;  4OUN A;  2NUG A;  1YZ9 A;  3RV0 A;  1U61 A;  2NUE A;  4M2Z A;  2FFL A;  1YYW A;  2GSL A;  1JFZ A;  1YYK A;  2QVW A;  3RV1 A;  1YYO A;  3O2R A;  1RC7 A;  1O0W A; 
#chains in the Genus database with same CATH homology
 1RC5 A;  3O2R B;  1I4S A;  4OOG C;  3C4B A;  3C4T A;  2NUF A;  4M30 A;  2EZ6 A;  2A11 A;  2EB1 A;  3N3W A;  4OUN A;  2NUG A;  1YZ9 A;  3RV0 A;  1U61 A;  2NUE A;  4M2Z A;  2FFL A;  1YYW A;  2GSL A;  1JFZ A;  1YYK A;  2QVW A;  3RV1 A;  1YYO A;  3O2R A;  1RC7 A;  1O0W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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