1KICA

Inosine-adenosine-guanosine preferring nucleoside hydrolase from trypanosoma vivax: asp10ala mutant in complex with inosine
Total Genus 122
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
327
structure length
317
Chain Sequence
SAKNVVLDHAGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords inosine-adenosine-guanosine preferring nucleoside hydrolase
publication title Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.
pubmed doi rcsb
source organism Trypanosoma vivax
total genus 122
structure length 317
sequence length 327
chains with identical sequence B
ec nomenclature ec 3.2.2.1: Purine nucleosidase.
pdb deposition date 2001-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01156 IU_nuc_hydro Inosine-uridine preferring nucleoside hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.245.10 Alpha Beta Alpha-Beta Complex Inosine-uridine Nucleoside N-ribohydrolase; Chain A Ribonucleoside hydrolase-like 1kicA00
3G5IA 4KPOA 4KPNA 3FZ0A 2FF1A 3MKNA 3EPWA 3B9GA 2FF2A 4P5FA 3EPXA 1HOZA 3T8IA 3T8JA 4I73A 4I75A 4I74A 2C40A 1KIEA 2YHGA 2MASA 3B9XA 1EZRA 4I72A 1YOEA 4I70A 4WR2A 4KL0A 4I71A 3MKMA 5TSQA 1HP0A 1KICA 1R4FA 1Q8FA 1MASA
chains in the Genus database with same CATH superfamily
3G5IA 4KPOA 4KPNA 3FZ0A 2FF1A 3MKNA 3EPWA 3B9GA 2FF2A 4P5FA 3EPXA 1HOZA 3T8IA 3T8JA 4I73A 4I75A 4I74A 2C40A 1KIEA 2YHGA 2MASA 3B9XA 1EZRA 4I72A 1YOEA 4I70A 4WR2A 4KL0A 4I71A 3MKMA 5TSQA 1HP0A 1KICA 1R4FA 1Q8FA 1MASA
chains in the Genus database with same CATH topology
3G5IA 4KPOA 4KPNA 3FZ0A 2FF1A 3MKNA 3EPWA 3B9GA 2FF2A 4P5FA 3EPXA 1HOZA 3T8IA 3T8JA 4I73A 4I75A 4I74A 2C40A 1KIEA 2YHGA 2MASA 3B9XA 1EZRA 4I72A 1YOEA 4I70A 4WR2A 4KL0A 4I71A 3MKMA 5TSQA 1HP0A 1KICA 1R4FA 1Q8FA 1MASA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G5I A;  4KPO A;  4KPN A;  3FZ0 A;  2FF1 A;  3MKN A;  3EPW A;  3B9G A;  2FF2 A;  4P5F A;  3EPX A;  1HOZ A;  3T8I A;  3T8J A;  4I73 A;  4I75 A;  4I74 A;  2C40 A;  1KIE A;  2YHG A;  2MAS A;  3B9X A;  1EZR A;  4I72 A;  1YOE A;  4I70 A;  4WR2 A;  4KL0 A;  4I71 A;  3MKM A;  5TSQ A;  1HP0 A;  1KIC A;  1R4F A;  1Q8F A;  1MAS A; 
#chains in the Genus database with same CATH topology
 3G5I A;  4KPO A;  4KPN A;  3FZ0 A;  2FF1 A;  3MKN A;  3EPW A;  3B9G A;  2FF2 A;  4P5F A;  3EPX A;  1HOZ A;  3T8I A;  3T8J A;  4I73 A;  4I75 A;  4I74 A;  2C40 A;  1KIE A;  2YHG A;  2MAS A;  3B9X A;  1EZR A;  4I72 A;  1YOE A;  4I70 A;  4WR2 A;  4KL0 A;  4I71 A;  3MKM A;  5TSQ A;  1HP0 A;  1KIC A;  1R4F A;  1Q8F A;  1MAS A; 
#chains in the Genus database with same CATH homology
 3G5I A;  4KPO A;  4KPN A;  3FZ0 A;  2FF1 A;  3MKN A;  3EPW A;  3B9G A;  2FF2 A;  4P5F A;  3EPX A;  1HOZ A;  3T8I A;  3T8J A;  4I73 A;  4I75 A;  4I74 A;  2C40 A;  1KIE A;  2YHG A;  2MAS A;  3B9X A;  1EZR A;  4I72 A;  1YOE A;  4I70 A;  4WR2 A;  4KL0 A;  4I71 A;  3MKM A;  5TSQ A;  1HP0 A;  1KIC A;  1R4F A;  1Q8F A;  1MAS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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