1S0WC

1b lactamse/ b lactamase inhibitor
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
165
structure length
165
Chain Sequence
AGVMTGAKFTQIQFGMTRQQVLDIAGAENCETGGSFGDSIHCRGHAAGDYYAYATFGFTSAAADAKVDSKSQEKLLAPSAPTLTLAKFNQVTVGMTRAQVLATVGQGSCTTWSEYYPAYPSTAGVTLSLSCFDVDGYSSTGAYRGSAHLWFTDGVLQGKRQWDLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords beta-lactamase TEM
publication title The modular architecture of protein-protein binding interfaces.
pubmed doi rcsb
source organism Escherichia coli
total genus 48
structure length 165
sequence length 165
chains with identical sequence D
ec nomenclature
pdb deposition date 2004-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07467 BLIP Beta-lactamase inhibitor (BLIP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 1s0wC02
3.30.1450.10 Alpha Beta 2-Layer Sandwich Beta-lactamase Inhibitory Protein; Chain:B, domain 1 Beta-lactamase Inhibitory Protein; Chain:B, domain 1 1s0wC01
5EKQE 3N4IB 3D4EA 5AYWE 2B5RC 1XXMC 1JTGB 3E2LC 2PXGA 5D0OE 2YH9A 2G2WB 3GMUB 2KM7A 1S0WC 2KXXA 3C4OB 3C4PB 5D0QE 3C7VB 4DM5A 2G2UB 3C7UB 3E2KC
chains in the Genus database with same CATH superfamily
5EKQE 3NWFA 3N4IB 3D4EA 4HSIA 3NWAA 3NW8A 5AYWE 2GUMA 2B5RC 1XXMC 1JTGB 4L1RA 3E2LC 2PXGA 5D0OE 2YH9A 2G2WB 3GMUB 2KM7A 3FVCA 1S0WC 2KXXA 3C4OB 3C4PB 5D0QE 3C7VB 4DM5A 2G2UB 3NWDA 3C7UB 3E2KC
chains in the Genus database with same CATH topology
5EKQE 3NWFA 3N4IB 3D4EA 4HSIA 3NWAA 3NW8A 5AYWE 2GUMA 2B5RC 1XXMC 1JTGB 4L1RA 3E2LC 2PXGA 5D0OE 2YH9A 2G2WB 3GMUB 2KM7A 3FVCA 1S0WC 2KXXA 3C4OB 3C4PB 5D0QE 3C7VB 4DM5A 2G2UB 3NWDA 3C7UB 3E2KC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EKQ E;  3N4I B;  3D4E A;  5AYW E;  2B5R C;  1XXM C;  1JTG B;  3E2L C;  2PXG A;  5D0O E;  2YH9 A;  2G2W B;  3GMU B;  2KM7 A;  1S0W C;  2KXX A;  3C4O B;  3C4P B;  5D0Q E;  3C7V B;  4DM5 A;  2G2U B;  3C7U B;  3E2K C; 
#chains in the Genus database with same CATH topology
 5EKQ E;  3NWF A;  3N4I B;  3D4E A;  4HSI A;  3NWA A;  3NW8 A;  5AYW E;  2GUM A;  2B5R C;  1XXM C;  1JTG B;  4L1R A;  3E2L C;  2PXG A;  5D0O E;  2YH9 A;  2G2W B;  3GMU B;  2KM7 A;  3FVC A;  1S0W C;  2KXX A;  3C4O B;  3C4P B;  5D0Q E;  3C7V B;  4DM5 A;  2G2U B;  3NWD A;  3C7U B;  3E2K C; 
#chains in the Genus database with same CATH homology
 5EKQ E;  3NWF A;  3N4I B;  3D4E A;  4HSI A;  3NWA A;  3NW8 A;  5AYW E;  2GUM A;  2B5R C;  1XXM C;  1JTG B;  4L1R A;  3E2L C;  2PXG A;  5D0O E;  2YH9 A;  2G2W B;  3GMU B;  2KM7 A;  3FVC A;  1S0W C;  2KXX A;  3C4O B;  3C4P B;  5D0Q E;  3C7V B;  4DM5 A;  2G2U B;  3NWD A;  3C7U B;  3E2K C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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