1XK9A

Pseudomanas exotoxin a in complex with the pj34 inhibitor
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
204
structure length
204
Chain Sequence
EFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Exotoxin A
publication title Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 50
structure length 204
sequence length 204
chains with identical sequence B
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2004-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09009 Exotox-A_cataly Exotoxin A catalytic
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 1xk9A00
4AE0A 3KI5A 3ESSA 1DMAA 3Q9OA 1TOXA 1ZM4B 5I82A 3KI1A 1ZM2B 1XDTT 2ZITB 1XK9A 3KI7A 3KI4A 3KI3A 1DTPA 1MDTA 2Q6MA 3KI6A 4OW6A 1ZM3B 2Q5TA 1ZM9B 1AERA 3KI0A 3NY6A 3KI2A 1DDTA 1IKQA 3B82B 4AE1A 1F0LA 1SGKA 3B8HB 3B78B 1IKPA
chains in the Genus database with same CATH superfamily
4AE0A 3KI5A 3ESSA 1DMAA 3Q9OA 1TOXA 1ZM4B 5I82A 3KI1A 1ZM2B 1XDTT 2ZITB 1XK9A 3KI7A 3KI4A 3KI3A 1DTPA 1MDTA 2Q6MA 3KI6A 4OW6A 1ZM3B 2Q5TA 1ZM9B 1AERA 3KI0A 3NY6A 3KI2A 1DDTA 1IKQA 3B82B 4AE1A 1F0LA 1SGKA 3B8HB 3B78B 1IKPA
chains in the Genus database with same CATH topology
4AE0A 3KI5A 3ESSA 1DMAA 3Q9OA 1TOXA 1ZM4B 5I82A 3KI1A 1ZM2B 1XDTT 2ZITB 1XK9A 3KI7A 3KI4A 3KI3A 1DTPA 1MDTA 2Q6MA 3KI6A 4OW6A 1ZM3B 2Q5TA 1ZM9B 1AERA 3KI0A 3NY6A 3KI2A 1DDTA 1IKQA 3B82B 4AE1A 1F0LA 1SGKA 3B8HB 3B78B 1IKPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AE0 A;  3KI5 A;  3ESS A;  1DMA A;  3Q9O A;  1TOX A;  1ZM4 B;  5I82 A;  3KI1 A;  1ZM2 B;  1XDT T;  2ZIT B;  1XK9 A;  3KI7 A;  3KI4 A;  3KI3 A;  1DTP A;  1MDT A;  2Q6M A;  3KI6 A;  4OW6 A;  1ZM3 B;  2Q5T A;  1ZM9 B;  1AER A;  3KI0 A;  3NY6 A;  3KI2 A;  1DDT A;  1IKQ A;  3B82 B;  4AE1 A;  1F0L A;  1SGK A;  3B8H B;  3B78 B;  1IKP A; 
#chains in the Genus database with same CATH topology
 4AE0 A;  3KI5 A;  3ESS A;  1DMA A;  3Q9O A;  1TOX A;  1ZM4 B;  5I82 A;  3KI1 A;  1ZM2 B;  1XDT T;  2ZIT B;  1XK9 A;  3KI7 A;  3KI4 A;  3KI3 A;  1DTP A;  1MDT A;  2Q6M A;  3KI6 A;  4OW6 A;  1ZM3 B;  2Q5T A;  1ZM9 B;  1AER A;  3KI0 A;  3NY6 A;  3KI2 A;  1DDT A;  1IKQ A;  3B82 B;  4AE1 A;  1F0L A;  1SGK A;  3B8H B;  3B78 B;  1IKP A; 
#chains in the Genus database with same CATH homology
 4AE0 A;  3KI5 A;  3ESS A;  1DMA A;  3Q9O A;  1TOX A;  1ZM4 B;  5I82 A;  3KI1 A;  1ZM2 B;  1XDT T;  2ZIT B;  1XK9 A;  3KI7 A;  3KI4 A;  3KI3 A;  1DTP A;  1MDT A;  2Q6M A;  3KI6 A;  4OW6 A;  1ZM3 B;  2Q5T A;  1ZM9 B;  1AER A;  3KI0 A;  3NY6 A;  3KI2 A;  1DDT A;  1IKQ A;  3B82 B;  4AE1 A;  1F0L A;  1SGK A;  3B8H B;  3B78 B;  1IKP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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