3ESSA

Catalytic fragment of cholix toxin from vibrio cholerae in complex with the 1,8-naphthalimide inhibitor
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
208
structure length
199
Chain Sequence
MAVITPQGVTNWTYQELEATHQALTREGYVFVGYHGTNHVAAQTIVNRIAPVEKWGGLYVATHAEVAHGYARIKEGTGEYGLPTRAERDARGVMLRVYIPRASLERFYRTNTPLENAEEHITQVIGHSLPLRNEAFTGPESAGGEDETVIGWDMAIHAVAIPSTIPGNAYEELAIDEEAVAKEQSISTKPPYKERKDEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase,toxin
molecule keywords Cholix toxin
publication title Yeast as a tool for characterizing mono-ADP-ribosyltransferase toxins
pubmed doi rcsb
source organism Vibrio cholerae
total genus 54
structure length 199
sequence length 208
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2008-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09009 Exotox-A_cataly Exotoxin A catalytic
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 3essA00
4AE0A 3KI5A 3ESSA 1DMAA 3Q9OA 1TOXA 1ZM4B 5I82A 3KI1A 1ZM2B 1XDTT 2ZITB 1XK9A 3KI7A 3KI4A 3KI3A 1DTPA 1MDTA 2Q6MA 3KI6A 4OW6A 1ZM3B 2Q5TA 1ZM9B 1AERA 3KI0A 3NY6A 3KI2A 1DDTA 1IKQA 3B82B 4AE1A 1F0LA 1SGKA 3B8HB 3B78B 1IKPA
chains in the Genus database with same CATH superfamily
4AE0A 3KI5A 3ESSA 1DMAA 3Q9OA 1TOXA 1ZM4B 5I82A 3KI1A 1ZM2B 1XDTT 2ZITB 1XK9A 3KI7A 3KI4A 3KI3A 1DTPA 1MDTA 2Q6MA 3KI6A 4OW6A 1ZM3B 2Q5TA 1ZM9B 1AERA 3KI0A 3NY6A 3KI2A 1DDTA 1IKQA 3B82B 4AE1A 1F0LA 1SGKA 3B8HB 3B78B 1IKPA
chains in the Genus database with same CATH topology
4AE0A 3KI5A 3ESSA 1DMAA 3Q9OA 1TOXA 1ZM4B 5I82A 3KI1A 1ZM2B 1XDTT 2ZITB 1XK9A 3KI7A 3KI4A 3KI3A 1DTPA 1MDTA 2Q6MA 3KI6A 4OW6A 1ZM3B 2Q5TA 1ZM9B 1AERA 3KI0A 3NY6A 3KI2A 1DDTA 1IKQA 3B82B 4AE1A 1F0LA 1SGKA 3B8HB 3B78B 1IKPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AE0 A;  3KI5 A;  3ESS A;  1DMA A;  3Q9O A;  1TOX A;  1ZM4 B;  5I82 A;  3KI1 A;  1ZM2 B;  1XDT T;  2ZIT B;  1XK9 A;  3KI7 A;  3KI4 A;  3KI3 A;  1DTP A;  1MDT A;  2Q6M A;  3KI6 A;  4OW6 A;  1ZM3 B;  2Q5T A;  1ZM9 B;  1AER A;  3KI0 A;  3NY6 A;  3KI2 A;  1DDT A;  1IKQ A;  3B82 B;  4AE1 A;  1F0L A;  1SGK A;  3B8H B;  3B78 B;  1IKP A; 
#chains in the Genus database with same CATH topology
 4AE0 A;  3KI5 A;  3ESS A;  1DMA A;  3Q9O A;  1TOX A;  1ZM4 B;  5I82 A;  3KI1 A;  1ZM2 B;  1XDT T;  2ZIT B;  1XK9 A;  3KI7 A;  3KI4 A;  3KI3 A;  1DTP A;  1MDT A;  2Q6M A;  3KI6 A;  4OW6 A;  1ZM3 B;  2Q5T A;  1ZM9 B;  1AER A;  3KI0 A;  3NY6 A;  3KI2 A;  1DDT A;  1IKQ A;  3B82 B;  4AE1 A;  1F0L A;  1SGK A;  3B8H B;  3B78 B;  1IKP A; 
#chains in the Genus database with same CATH homology
 4AE0 A;  3KI5 A;  3ESS A;  1DMA A;  3Q9O A;  1TOX A;  1ZM4 B;  5I82 A;  3KI1 A;  1ZM2 B;  1XDT T;  2ZIT B;  1XK9 A;  3KI7 A;  3KI4 A;  3KI3 A;  1DTP A;  1MDT A;  2Q6M A;  3KI6 A;  4OW6 A;  1ZM3 B;  2Q5T A;  1ZM9 B;  1AER A;  3KI0 A;  3NY6 A;  3KI2 A;  1DDT A;  1IKQ A;  3B82 B;  4AE1 A;  1F0L A;  1SGK A;  3B8H B;  3B78 B;  1IKP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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