1XD3A

Crystal structure of uchl3-ubvme complex
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
Knots found
sequence length
229
structure length
229
Chain Sequence
EGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Ubiquitin Carboxyl-terminal esterase L3
total genus 81
structure length 229
sequence length 229
chains with identical sequence C
other databases KnotProt 2.0: K -52 -31 -31
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2004-09-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01088 Peptidase_C12 Ubiquitin carboxyl-terminal hydrolase, family 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.532.10 Alpha Beta 3-Layer(aba) Sandwich Ubiquitin C-terminal Hydrolase UCH-l3 Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1xd3A00
4UELA 3KW5A 3IRTA 3RIIA 4I6NA 2ETLA 3A7SA 4DM9A 1UCHA 3IFWA 4JKJA 3KVFA 3IHRA 3TB3A 4UEMA 1XD3A 4IG7A 3RISA 2LENA 1CMXA
chains in the Genus database with same CATH superfamily
4UELA 3KW5A 3IRTA 3RIIA 4I6NA 2ETLA 3A7SA 4DM9A 1UCHA 3IFWA 4JKJA 3KVFA 3IHRA 3TB3A 4UEMA 1XD3A 4IG7A 3RISA 2LENA 1CMXA
chains in the Genus database with same CATH topology
4UELA 3KW5A 3IRTA 3RIIA 4I6NA 2ETLA 3A7SA 4DM9A 1UCHA 3IFWA 4JKJA 3KVFA 3IHRA 3TB3A 4UEMA 1XD3A 4IG7A 3RISA 2LENA 1CMXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UEL A;  3KW5 A;  3IRT A;  3RII A;  4I6N A;  2ETL A;  3A7S A;  4DM9 A;  1UCH A;  3IFW A;  4JKJ A;  3KVF A;  3IHR A;  3TB3 A;  4UEM A;  1XD3 A;  4IG7 A;  3RIS A;  2LEN A;  1CMX A; 
#chains in the Genus database with same CATH topology
 4UEL A;  3KW5 A;  3IRT A;  3RII A;  4I6N A;  2ETL A;  3A7S A;  4DM9 A;  1UCH A;  3IFW A;  4JKJ A;  3KVF A;  3IHR A;  3TB3 A;  4UEM A;  1XD3 A;  4IG7 A;  3RIS A;  2LEN A;  1CMX A; 
#chains in the Genus database with same CATH homology
 4UEL A;  3KW5 A;  3IRT A;  3RII A;  4I6N A;  2ETL A;  3A7S A;  4DM9 A;  1UCH A;  3IFW A;  4JKJ A;  3KVF A;  3IHR A;  3TB3 A;  4UEM A;  1XD3 A;  4IG7 A;  3RIS A;  2LEN A;  1CMX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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