2GWDA

Crystal structure of plant glutamate cysteine ligase in complex with mg2+ and l-glutamate
Total Genus 159
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
159
sequence length
436
structure length
436
Chain Sequence
EPLTREDLIAYLASGCKSKEKWRIGTEHEKFGFEVNTLRPMKYDQIAELLNSIAERFEWEKVMEGDKIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGMGFQPKWRREDIPTMPKGRYDIMRNYMPKVGSLGLDMMLRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTEGKPNGFLSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDYALDVPMYFAYRNGKYVDCTGMTFRQFLAGKLPCLPGELPTYNDWENHLTTIFPEVRLKRYMEMRGADGGPWRRLCALPAFWVGLLYDEDVLQSVLDLTADWTPAEREMLRNKVPVTGLKTPFRDGLLKHVAEDVLKLAKDGLERRGYKEVGFLNAVTEVVRTGVTPAENLLEMYNGEWGQSVDPVFQELLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords Glutamate cysteine ligase
publication title Structural basis for the redox control of plant glutamate cysteine ligase.
pubmed doi rcsb
source organism Brassica juncea
total genus 159
structure length 436
sequence length 436
ec nomenclature ec 6.3.2.2: Glutamate--cysteine ligase.
pdb deposition date 2006-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04107 GCS2 Glutamate-cysteine ligase family 2(GCS2)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.590.20 Alpha Beta 2-Layer Sandwich Creatine Kinase; Chain A, domain 2 Creatine Kinase; Chain A, domain 2 2gwdA00
3LN6A 1V4GA 1R8GA 1TT4A 1VA6A 2D32A 3NZTA 2GWDA 2GWCA 3LN7A 2D33A
chains in the Genus database with same CATH superfamily
4LNKA 4LNFA 3L2DA 4RF8A 4BG4A 4RF7A 3LVVA 1G0WA 3B6RA 3ZXRA 1U6RA 2UU7A 1M15A 3NG0A 4GVYA 4AM1A 4GW2A 1FPYA 3L2EB 2GWCA 1LGRA 3JPZA 4RF6A 2D32A 2OJWA 3LN7A 2D3BA 1BG0A 1HTQA 3LN6A 3JQ3A 2J1QA 1SD0A 3IG8A 4XYCA 1VA6A 3JU5A 4LNIA 2GLSA 4Z9MA 1F1HA 4RF9A 3L2EA 3ZXVA 2D3CA 3FKYA 4BHLA 2D33A 1V4GA 5J9AA 1QH4A 1RL9A 4LNOA 1HTOA 4ACFA 2WGSA 1CRKA 3DRBA 4HPPA 1F52A 3LVWA 4Q2RA 2LGSA 4S0RA 3M10A 2BVCA 1I0EA 3IG5A 3DREA 4BAXA 2GWDA 4BG4B 2WHIA 1QK1A 1P52A 4S17A 2CRKA 3NZTA 3JU6A 2D3AA 1P50A 5J99A 1VRPA 2QC8A 1R8GA 1TT4A 4GW0A 4LNNA 4GVZA
chains in the Genus database with same CATH topology
3LN6A 1V4GA 3NZTA 3LVVA 2UU7A 3IG8A 1VA6A 2D3AA 2GWCA 3LVWA 2D32A 2QC8A 2OJWA 3LN7A 2D3CA 2D3BA 1R8GA 1TT4A 3FKYA 3IG5A 4BAXA 2GWDA 2D33A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LN6 A;  1V4G A;  1R8G A;  1TT4 A;  1VA6 A;  2D32 A;  3NZT A;  2GWD A;  2GWC A;  3LN7 A;  2D33 A; 
#chains in the Genus database with same CATH topology
 4LNK A;  4LNF A;  3L2D A;  4RF8 A;  4BG4 A;  4RF7 A;  3LVV A;  1G0W A;  3B6R A;  3ZXR A;  1U6R A;  2UU7 A;  1M15 A;  3NG0 A;  4GVY A;  4AM1 A;  4GW2 A;  1FPY A;  3L2E B;  2GWC A;  1LGR A;  3JPZ A;  4RF6 A;  2D32 A;  2OJW A;  3LN7 A;  2D3B A;  1BG0 A;  1HTQ A;  3LN6 A;  3JQ3 A;  2J1Q A;  1SD0 A;  3IG8 A;  4XYC A;  1VA6 A;  3JU5 A;  4LNI A;  2GLS A;  4Z9M A;  1F1H A;  4RF9 A;  3L2E A;  3ZXV A;  2D3C A;  3FKY A;  4BHL A;  2D33 A;  1V4G A;  5J9A A;  1QH4 A;  1RL9 A;  4LNO A;  1HTO A;  4ACF A;  2WGS A;  1CRK A;  3DRB A;  4HPP A;  1F52 A;  3LVW A;  4Q2R A;  2LGS A;  4S0R A;  3M10 A;  2BVC A;  1I0E A;  3IG5 A;  3DRE A;  4BAX A;  2GWD A;  4BG4 B;  2WHI A;  1QK1 A;  1P52 A;  4S17 A;  2CRK A;  3NZT A;  3JU6 A;  2D3A A;  1P50 A;  5J99 A;  1VRP A;  2QC8 A;  1R8G A;  1TT4 A;  4GW0 A;  4LNN A;  4GVZ A; 
#chains in the Genus database with same CATH homology
 3LN6 A;  1V4G A;  3NZT A;  3LVV A;  2UU7 A;  3IG8 A;  1VA6 A;  2D3A A;  2GWC A;  3LVW A;  2D32 A;  2QC8 A;  2OJW A;  3LN7 A;  2D3C A;  2D3B A;  1R8G A;  1TT4 A;  3FKY A;  3IG5 A;  4BAX A;  2GWD A;  2D33 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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