2LFKA

Nmr solution structure of native tdpi-short
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
57
structure length
57
Chain Sequence
GDKEECTVPIGWSEPVKGLCKARFTRYYCMGNCCKVYEGCYTGGYSRMGECARNCPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase inhibitor
molecule keywords Tryptase inhibitor
publication title Oxidative folding and structural analyses of a kunitz-related inhibitor and its disulfide intermediates: functional implications.
pubmed doi rcsb
source organism Rhipicephalus appendiculatus
total genus 3
structure length 57
sequence length 57
ec nomenclature
pdb deposition date 2011-07-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2lfkA01
3L3TE 2UUYB 1PITA 2LFLA 1DTXA 1KTHA 1OA55 2FI3I 1DTKA 1P2KI 3CI7A 4U30W 3TGJI 3D65I 3AUDA 1JV9A 1TOCR 1ZR0B 1NAGA 3AUIA 1BF0A 1JV8A 2LFKA 1UUBA 2UUXA 2M01A 2FTLI 1BZXI 2HEXA 3FP6I 1P2QB 3AUHA 1EJMB 1D0DB 1G6XA 1F7ZI 1JC6A 3UOUB 3AUBA 3BTDI 1ADZA 5JB7A 3AUGA 5JB4A 3FP7J 1T8LB 1TPAI 1TFXC 9PTIA 3BTFI 1LD5A 1YC0I 2ZJXA 3BTHI 4ISLB 2CA7A 1P2OB 1SHPA 5JB5A 3WNYA 1IRHA 1EAWB 3FP8I 3TGKI 1OA65 1UUAA 1F5RI 3P92E 1CBWD 1BPTA 1BTHP 1KNTA 3LDJA 2J6DA 3T62D 7PTIA 3GYMI 1BPIA 1MTND 1BUNB 6PTIA 4BNRI 1CA0D 3AUCA 4ISOB 3AUEA 1BZ5A 2KNTA 1P2II 3BTMI 2ODYE 1K6UA 2TPII 4TPII 4Y10I 4DG4C 1BHCA 1FANA 2PTCI 2DDJA 4WXVC 4Y0ZI 1TCPA 2R9PE 3UIRC 2ZVXA 4BD9B 2KAII 3BYBA 5JB6A 1QLQA 2IJOI 1P2MB 1B0CA 3BTQI 1YKTB 3BTGI 1Y62A 3P95E 3U1JE 2FI5I 2KCRA 5PTIA 1BRCI 1T8MB 4WWYC 1YLCB 2DDIA 5C67C 1P2JI 3OTJI 3BTWI 4NTWB 1BTIA 1AALA 1DENA 1T7CB 4NTYB 1TAWB 2TGPI 1DEMA 3M7QB 4NTXB 4U32X 4DTGK 1P2NB 1T8NB 1KIGI 2FI4I 2W8XA 3TGII 3L33E 4Y0YI 3TPII 1D0DA 2RA3C 4ISNB 3OFWA 1KUNA 1BIKA 1YLDB 4BQDA 3LDIA 1AAPA 1FAKI 3BTTI 1TAPA 4Y11I 1FY8I 1ZJDB 1T8OB 2JOTA 1LD6A 1CO7I 8PTIA 1BRBI 3BTEI 3LDMA 2M99A 4PTIA 2FTMB 3BTKI
chains in the Genus database with same CATH superfamily
3L3TE 2UUYB 1PITA 2LFLA 1DTXA 1KTHA 1OA55 2FI3I 1DTKA 1P2KI 3CI7A 4U30W 3TGJI 3D65I 3AUDA 1JV9A 1TOCR 1ZR0B 1NAGA 3AUIA 1BF0A 1JV8A 2LFKA 1UUBA 2UUXA 2M01A 2FTLI 1BZXI 2HEXA 3FP6I 1P2QB 3AUHA 1EJMB 1D0DB 1G6XA 1F7ZI 1JC6A 3UOUB 3AUBA 3BTDI 1ADZA 5JB7A 3AUGA 5JB4A 3FP7J 1T8LB 1TPAI 1TFXC 9PTIA 3BTFI 1LD5A 1YC0I 2ZJXA 3BTHI 4ISLB 2CA7A 1P2OB 1SHPA 5JB5A 3WNYA 1IRHA 1EAWB 3FP8I 3TGKI 1OA65 1UUAA 1F5RI 3P92E 1CBWD 1BPTA 1BTHP 1KNTA 3LDJA 2J6DA 3T62D 7PTIA 3GYMI 1BPIA 1MTND 1BUNB 6PTIA 4BNRI 1CA0D 3AUCA 4ISOB 3AUEA 1BZ5A 2KNTA 1P2II 3BTMI 2ODYE 1K6UA 2TPII 4TPII 4Y10I 4DG4C 1BHCA 1FANA 2PTCI 2DDJA 4WXVC 4Y0ZI 1TCPA 2R9PE 3UIRC 2ZVXA 4BD9B 2KAII 3BYBA 5JB6A 1QLQA 2IJOI 1P2MB 1B0CA 3BTQI 1YKTB 3BTGI 1Y62A 3P95E 3U1JE 2FI5I 2KCRA 5PTIA 1BRCI 1T8MB 4WWYC 1YLCB 2DDIA 5C67C 1P2JI 3OTJI 3BTWI 4NTWB 1BTIA 1AALA 1DENA 1T7CB 4NTYB 1TAWB 2TGPI 1DEMA 3M7QB 4NTXB 4U32X 4DTGK 1P2NB 1T8NB 1KIGI 2FI4I 2W8XA 3TGII 3L33E 4Y0YI 3TPII 1D0DA 2RA3C 4ISNB 3OFWA 1KUNA 1BIKA 1YLDB 4BQDA 3LDIA 1AAPA 1FAKI 3BTTI 1TAPA 4Y11I 1FY8I 1ZJDB 1T8OB 2JOTA 1LD6A 1CO7I 8PTIA 1BRBI 3BTEI 3LDMA 2M99A 4PTIA 2FTMB 3BTKI
chains in the Genus database with same CATH topology
3L3TE 2UUYB 1PITA 2LFLA 1DTXA 1KTHA 1OA55 2FI3I 1DTKA 1P2KI 3CI7A 4U30W 3TGJI 3D65I 3AUDA 1JV9A 1TOCR 1ZR0B 1NAGA 3AUIA 1BF0A 1JV8A 2LFKA 1UUBA 2UUXA 2M01A 2FTLI 1BZXI 2HEXA 3FP6I 1P2QB 3AUHA 1EJMB 1D0DB 1G6XA 1F7ZI 1JC6A 3UOUB 3AUBA 3BTDI 1ADZA 5JB7A 3AUGA 5JB4A 3FP7J 1T8LB 1TPAI 1TFXC 9PTIA 3BTFI 1LD5A 1YC0I 2ZJXA 3BTHI 4ISLB 2CA7A 1P2OB 1SHPA 5JB5A 3WNYA 1IRHA 1EAWB 3FP8I 3TGKI 1OA65 1UUAA 1F5RI 3P92E 1CBWD 1BPTA 1BTHP 1KNTA 3LDJA 2J6DA 3T62D 7PTIA 3GYMI 1BPIA 1MTND 1BUNB 6PTIA 4BNRI 1CA0D 3AUCA 4ISOB 3AUEA 1BZ5A 2KNTA 1P2II 3BTMI 2ODYE 1K6UA 2TPII 4TPII 4Y10I 4DG4C 1BHCA 1FANA 2PTCI 2DDJA 4WXVC 4Y0ZI 1TCPA 2R9PE 3UIRC 2ZVXA 4BD9B 2KAII 3BYBA 5JB6A 1QLQA 2IJOI 1P2MB 1B0CA 3BTQI 1YKTB 3BTGI 1Y62A 3P95E 3U1JE 2FI5I 2KCRA 5PTIA 1BRCI 1T8MB 4WWYC 1YLCB 2DDIA 5C67C 1P2JI 3OTJI 3BTWI 4NTWB 1BTIA 1AALA 1DENA 1T7CB 4NTYB 1TAWB 2TGPI 1DEMA 3M7QB 4NTXB 4U32X 4DTGK 1P2NB 1T8NB 1KIGI 2FI4I 2W8XA 3TGII 3L33E 4Y0YI 3TPII 1D0DA 2RA3C 4ISNB 3OFWA 1KUNA 1BIKA 1YLDB 4BQDA 3LDIA 1AAPA 1FAKI 3BTTI 1TAPA 4Y11I 1FY8I 1ZJDB 1T8OB 2JOTA 1LD6A 1CO7I 8PTIA 1BRBI 3BTEI 3LDMA 2M99A 4PTIA 2FTMB 3BTKI
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3L3T E;  2UUY B;  1PIT A;  2LFL A;  1DTX A;  1KTH A;  1OA5 5;  2FI3 I;  1DTK A;  1P2K I;  3CI7 A;  4U30 W;  3TGJ I;  3D65 I;  3AUD A;  1JV9 A;  1TOC R;  1ZR0 B;  1NAG A;  3AUI A;  1BF0 A;  1JV8 A;  2LFK A;  1UUB A;  2UUX A;  2M01 A;  2FTL I;  1BZX I;  2HEX A;  3FP6 I;  1P2Q B;  3AUH A;  1EJM B;  1D0D B;  1G6X A;  1F7Z I;  1JC6 A;  3UOU B;  3AUB A;  3BTD I;  1ADZ A;  5JB7 A;  3AUG A;  5JB4 A;  3FP7 J;  1T8L B;  1TPA I;  1TFX C;  9PTI A;  3BTF I;  1LD5 A;  1YC0 I;  2ZJX A;  3BTH I;  4ISL B;  2CA7 A;  1P2O B;  1SHP A;  5JB5 A;  3WNY A;  1IRH A;  1EAW B;  3FP8 I;  3TGK I;  1OA6 5;  1UUA A;  1F5R I;  3P92 E;  1CBW D;  1BPT A;  1BTH P;  1KNT A;  3LDJ A;  2J6D A;  3T62 D;  7PTI A;  3GYM I;  1BPI A;  1MTN D;  1BUN B;  6PTI A;  4BNR I;  1CA0 D;  3AUC A;  4ISO B;  3AUE A;  1BZ5 A;  2KNT A;  1P2I I;  3BTM I;  2ODY E;  1K6U A;  2TPI I;  4TPI I;  4Y10 I;  4DG4 C;  1BHC A;  1FAN A;  2PTC I;  2DDJ A;  4WXV C;  4Y0Z I;  1TCP A;  2R9P E;  3UIR C;  2ZVX A;  4BD9 B;  2KAI I;  3BYB A;  5JB6 A;  1QLQ A;  2IJO I;  1P2M B;  1B0C A;  3BTQ I;  1YKT B;  3BTG I;  1Y62 A;  3P95 E;  3U1J E;  2FI5 I;  2KCR A;  5PTI A;  1BRC I;  1T8M B;  4WWY C;  1YLC B;  2DDI A;  5C67 C;  1P2J I;  3OTJ I;  3BTW I;  4NTW B;  1BTI A;  1AAL A;  1DEN A;  1T7C B;  4NTY B;  1TAW B;  2TGP I;  1DEM A;  3M7Q B;  4NTX B;  4U32 X;  4DTG K;  1P2N B;  1T8N B;  1KIG I;  2FI4 I;  2W8X A;  3TGI I;  3L33 E;  4Y0Y I;  3TPI I;  1D0D A;  2RA3 C;  4ISN B;  3OFW A;  1KUN A;  1BIK A;  1YLD B;  4BQD A;  3LDI A;  1AAP A;  1FAK I;  3BTT I;  1TAP A;  4Y11 I;  1FY8 I;  1ZJD B;  1T8O B;  2JOT A;  1LD6 A;  1CO7 I;  8PTI A;  1BRB I;  3BTE I;  3LDM A;  2M99 A;  4PTI A;  2FTM B;  3BTK I; 
#chains in the Genus database with same CATH topology
 3L3T E;  2UUY B;  1PIT A;  2LFL A;  1DTX A;  1KTH A;  1OA5 5;  2FI3 I;  1DTK A;  1P2K I;  3CI7 A;  4U30 W;  3TGJ I;  3D65 I;  3AUD A;  1JV9 A;  1TOC R;  1ZR0 B;  1NAG A;  3AUI A;  1BF0 A;  1JV8 A;  2LFK A;  1UUB A;  2UUX A;  2M01 A;  2FTL I;  1BZX I;  2HEX A;  3FP6 I;  1P2Q B;  3AUH A;  1EJM B;  1D0D B;  1G6X A;  1F7Z I;  1JC6 A;  3UOU B;  3AUB A;  3BTD I;  1ADZ A;  5JB7 A;  3AUG A;  5JB4 A;  3FP7 J;  1T8L B;  1TPA I;  1TFX C;  9PTI A;  3BTF I;  1LD5 A;  1YC0 I;  2ZJX A;  3BTH I;  4ISL B;  2CA7 A;  1P2O B;  1SHP A;  5JB5 A;  3WNY A;  1IRH A;  1EAW B;  3FP8 I;  3TGK I;  1OA6 5;  1UUA A;  1F5R I;  3P92 E;  1CBW D;  1BPT A;  1BTH P;  1KNT A;  3LDJ A;  2J6D A;  3T62 D;  7PTI A;  3GYM I;  1BPI A;  1MTN D;  1BUN B;  6PTI A;  4BNR I;  1CA0 D;  3AUC A;  4ISO B;  3AUE A;  1BZ5 A;  2KNT A;  1P2I I;  3BTM I;  2ODY E;  1K6U A;  2TPI I;  4TPI I;  4Y10 I;  4DG4 C;  1BHC A;  1FAN A;  2PTC I;  2DDJ A;  4WXV C;  4Y0Z I;  1TCP A;  2R9P E;  3UIR C;  2ZVX A;  4BD9 B;  2KAI I;  3BYB A;  5JB6 A;  1QLQ A;  2IJO I;  1P2M B;  1B0C A;  3BTQ I;  1YKT B;  3BTG I;  1Y62 A;  3P95 E;  3U1J E;  2FI5 I;  2KCR A;  5PTI A;  1BRC I;  1T8M B;  4WWY C;  1YLC B;  2DDI A;  5C67 C;  1P2J I;  3OTJ I;  3BTW I;  4NTW B;  1BTI A;  1AAL A;  1DEN A;  1T7C B;  4NTY B;  1TAW B;  2TGP I;  1DEM A;  3M7Q B;  4NTX B;  4U32 X;  4DTG K;  1P2N B;  1T8N B;  1KIG I;  2FI4 I;  2W8X A;  3TGI I;  3L33 E;  4Y0Y I;  3TPI I;  1D0D A;  2RA3 C;  4ISN B;  3OFW A;  1KUN A;  1BIK A;  1YLD B;  4BQD A;  3LDI A;  1AAP A;  1FAK I;  3BTT I;  1TAP A;  4Y11 I;  1FY8 I;  1ZJD B;  1T8O B;  2JOT A;  1LD6 A;  1CO7 I;  8PTI A;  1BRB I;  3BTE I;  3LDM A;  2M99 A;  4PTI A;  2FTM B;  3BTK I; 
#chains in the Genus database with same CATH homology
 3L3T E;  2UUY B;  1PIT A;  2LFL A;  1DTX A;  1KTH A;  1OA5 5;  2FI3 I;  1DTK A;  1P2K I;  3CI7 A;  4U30 W;  3TGJ I;  3D65 I;  3AUD A;  1JV9 A;  1TOC R;  1ZR0 B;  1NAG A;  3AUI A;  1BF0 A;  1JV8 A;  2LFK A;  1UUB A;  2UUX A;  2M01 A;  2FTL I;  1BZX I;  2HEX A;  3FP6 I;  1P2Q B;  3AUH A;  1EJM B;  1D0D B;  1G6X A;  1F7Z I;  1JC6 A;  3UOU B;  3AUB A;  3BTD I;  1ADZ A;  5JB7 A;  3AUG A;  5JB4 A;  3FP7 J;  1T8L B;  1TPA I;  1TFX C;  9PTI A;  3BTF I;  1LD5 A;  1YC0 I;  2ZJX A;  3BTH I;  4ISL B;  2CA7 A;  1P2O B;  1SHP A;  5JB5 A;  3WNY A;  1IRH A;  1EAW B;  3FP8 I;  3TGK I;  1OA6 5;  1UUA A;  1F5R I;  3P92 E;  1CBW D;  1BPT A;  1BTH P;  1KNT A;  3LDJ A;  2J6D A;  3T62 D;  7PTI A;  3GYM I;  1BPI A;  1MTN D;  1BUN B;  6PTI A;  4BNR I;  1CA0 D;  3AUC A;  4ISO B;  3AUE A;  1BZ5 A;  2KNT A;  1P2I I;  3BTM I;  2ODY E;  1K6U A;  2TPI I;  4TPI I;  4Y10 I;  4DG4 C;  1BHC A;  1FAN A;  2PTC I;  2DDJ A;  4WXV C;  4Y0Z I;  1TCP A;  2R9P E;  3UIR C;  2ZVX A;  4BD9 B;  2KAI I;  3BYB A;  5JB6 A;  1QLQ A;  2IJO I;  1P2M B;  1B0C A;  3BTQ I;  1YKT B;  3BTG I;  1Y62 A;  3P95 E;  3U1J E;  2FI5 I;  2KCR A;  5PTI A;  1BRC I;  1T8M B;  4WWY C;  1YLC B;  2DDI A;  5C67 C;  1P2J I;  3OTJ I;  3BTW I;  4NTW B;  1BTI A;  1AAL A;  1DEN A;  1T7C B;  4NTY B;  1TAW B;  2TGP I;  1DEM A;  3M7Q B;  4NTX B;  4U32 X;  4DTG K;  1P2N B;  1T8N B;  1KIG I;  2FI4 I;  2W8X A;  3TGI I;  3L33 E;  4Y0Y I;  3TPI I;  1D0D A;  2RA3 C;  4ISN B;  3OFW A;  1KUN A;  1BIK A;  1YLD B;  4BQD A;  3LDI A;  1AAP A;  1FAK I;  3BTT I;  1TAP A;  4Y11 I;  1FY8 I;  1ZJD B;  1T8O B;  2JOT A;  1LD6 A;  1CO7 I;  8PTI A;  1BRB I;  3BTE I;  3LDM A;  2M99 A;  4PTI A;  2FTM B;  3BTK I;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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