2VE7A

Crystal structure of a bonsai version of the human ndc80 complex
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
312
structure length
246
Chain Sequence
MIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQERSTANKANAERLKRLQKSADLYKDRLGLEIRFTNINPESPFRKAFTAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25
publication title Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
pubmed doi rcsb
source organism Homo sapiens
total genus 62
structure length 246
sequence length 312
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18077 DUF5595 Domain of unknown function (DUF5595)
A PF08234 Spindle_Spc25 Chromosome segregation protein Spc25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.30 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Actin-binding Protein, T-fimbrin; domain 1 2ve7A01
2IGPA 2VE7A
chains in the Genus database with same CATH superfamily
3VP7A 2D89A 3KMUB 1WYQA 1PA7A 2WA6A 1WYMA 4Q57B 1VKAA 1TJTA 4TXKA 1WYNA 2IGPA 1WIXA 4TXIA 3KMWB 1AOAA 2D87A 2EQOA 5A38A 1AA2A 4B7LA 2EE7A 4EDNA 1H67A 5FMUA 5J8EA 1SH5A 2R8UA 2JV9A 2VE7C 2K3SA 1WYRA 3HOPA 2E9KA 1WYPA 2VZIB 3I6XA 4LVPA 3HOCA 2L3GA 1UEGA 1SH6A 5BVRA 2D85A 1UJOA 2D86A 1WJOA 2EYNA 3FERA 2YRNA 2HKPA 1P2XA 3JAKM 4Q59A 1WYLA 3HORA 2HL8A 5FMTA 1BKRA 1WYOA 1WKUA 2D88A 2WA7A 2VZCA 1QAGA 2RR8A 2WDTA 1EUVA 2QJZA 2VE7A 4DDPA 4EDLA 1P5SA 1RT8A 1BHDA 1PXYA 3KY9A 3REPB 3CO1A 2DK9A 2WFNA 2VZGB 5A37A 1DXXA 2R0OA 3F7PA 4EDMA 3JARM 4LVRA 2HL9A 5A36A 1V5KA 2QJXA 2EYIA 3EAYA 5A4BA 3JALM 4Q58A 5L0OA 1MB8A 2WE6A 2K2RA 2WA5A 2VZDA
chains in the Genus database with same CATH topology
2EQOA 2VE7A 4LVPA 4LVRA 2IGPA 2HL9A 3VP7A 4DDPA 2WDTA 2WE6A 3EAYA 2HL8A 5FMTA 2VE7C 5FMUA 2HKPA 1EUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IGP A;  2VE7 A; 
#chains in the Genus database with same CATH topology
 3VP7 A;  2D89 A;  3KMU B;  1WYQ A;  1PA7 A;  2WA6 A;  1WYM A;  4Q57 B;  1VKA A;  1TJT A;  4TXK A;  1WYN A;  2IGP A;  1WIX A;  4TXI A;  3KMW B;  1AOA A;  2D87 A;  2EQO A;  5A38 A;  1AA2 A;  4B7L A;  2EE7 A;  4EDN A;  1H67 A;  5FMU A;  5J8E A;  1SH5 A;  2R8U A;  2JV9 A;  2VE7 C;  2K3S A;  1WYR A;  3HOP A;  2E9K A;  1WYP A;  2VZI B;  3I6X A;  4LVP A;  3HOC A;  2L3G A;  1UEG A;  1SH6 A;  5BVR A;  2D85 A;  1UJO A;  2D86 A;  1WJO A;  2EYN A;  3FER A;  2YRN A;  2HKP A;  1P2X A;  3JAK M;  4Q59 A;  1WYL A;  3HOR A;  2HL8 A;  5FMT A;  1BKR A;  1WYO A;  1WKU A;  2D88 A;  2WA7 A;  2VZC A;  1QAG A;  2RR8 A;  2WDT A;  1EUV A;  2QJZ A;  2VE7 A;  4DDP A;  4EDL A;  1P5S A;  1RT8 A;  1BHD A;  1PXY A;  3KY9 A;  3REP B;  3CO1 A;  2DK9 A;  2WFN A;  2VZG B;  5A37 A;  1DXX A;  2R0O A;  3F7P A;  4EDM A;  3JAR M;  4LVR A;  2HL9 A;  5A36 A;  1V5K A;  2QJX A;  2EYI A;  3EAY A;  5A4B A;  3JAL M;  4Q58 A;  5L0O A;  1MB8 A;  2WE6 A;  2K2R A;  2WA5 A;  2VZD A; 
#chains in the Genus database with same CATH homology
 2EQO A;  2VE7 A;  4LVP A;  4LVR A;  2IGP A;  2HL9 A;  3VP7 A;  4DDP A;  2WDT A;  2WE6 A;  3EAY A;  2HL8 A;  5FMT A;  2VE7 C;  5FMU A;  2HKP A;  1EUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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