2Z21A

Crystal structure of a five site mutated cyanovirin-n
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
102
structure length
102
Chain Sequence
LGNFSQACYNSAIQGSVLTSTCIRTNGGYNTSSIDLNSVIENVDGSLKWQGSNFIETCRNTQLAGSSELAAECKTRAQQFVSTKINLDDHIAAIDGTLKYEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Sugar binding protein
molecule keywords Cyanovirin-N
publication title A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity.
pubmed doi rcsb
source organism Nostoc ellipsosporum
total genus 26
structure length 102
sequence length 102
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08881 CVNH CVNH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.60.10 Mainly Beta Roll HIV-inactivating Protein, Cyanovirin-n Cyanovirin-N 2z21A00
2RP3A 3HNUX 3EZMA 4J4FA 2L2FA 2RDKA 3GXYA 1J4VA 3HP8A 2JZKA 2Y1SA 1LOMA 2L9YA 3S3YA 2JZJA 3LHCA 3CZZA 2PYSA 1L5EA 2JZLA 1IIYA 1N02A 2Z21A 5C8QB 3S3ZA 4J4CA 3GXZA 4J4EA 5C8OA 2EZNA 1L5BA 5C8PA 2EZMA 2KJLA 2YHHA 3HNXA
chains in the Genus database with same CATH superfamily
2RP3A 3HNUX 3EZMA 4J4FA 2L2FA 2RDKA 3GXYA 1J4VA 3HP8A 2JZKA 2Y1SA 1LOMA 2L9YA 3S3YA 2JZJA 3LHCA 3CZZA 2PYSA 1L5EA 2JZLA 1IIYA 1N02A 2Z21A 5C8QB 3S3ZA 4J4CA 3GXZA 4J4EA 5C8OA 2EZNA 1L5BA 5C8PA 2EZMA 2KJLA 2YHHA 3HNXA
chains in the Genus database with same CATH topology
2RP3A 3HNUX 3EZMA 4J4FA 2L2FA 2RDKA 3GXYA 1J4VA 3HP8A 2JZKA 2Y1SA 1LOMA 2L9YA 3S3YA 2JZJA 3LHCA 3CZZA 2PYSA 1L5EA 2JZLA 1IIYA 1N02A 2Z21A 5C8QB 3S3ZA 4J4CA 3GXZA 4J4EA 5C8OA 2EZNA 1L5BA 5C8PA 2EZMA 2KJLA 2YHHA 3HNXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RP3 A;  3HNU X;  3EZM A;  4J4F A;  2L2F A;  2RDK A;  3GXY A;  1J4V A;  3HP8 A;  2JZK A;  2Y1S A;  1LOM A;  2L9Y A;  3S3Y A;  2JZJ A;  3LHC A;  3CZZ A;  2PYS A;  1L5E A;  2JZL A;  1IIY A;  1N02 A;  2Z21 A;  5C8Q B;  3S3Z A;  4J4C A;  3GXZ A;  4J4E A;  5C8O A;  2EZN A;  1L5B A;  5C8P A;  2EZM A;  2KJL A;  2YHH A;  3HNX A; 
#chains in the Genus database with same CATH topology
 2RP3 A;  3HNU X;  3EZM A;  4J4F A;  2L2F A;  2RDK A;  3GXY A;  1J4V A;  3HP8 A;  2JZK A;  2Y1S A;  1LOM A;  2L9Y A;  3S3Y A;  2JZJ A;  3LHC A;  3CZZ A;  2PYS A;  1L5E A;  2JZL A;  1IIY A;  1N02 A;  2Z21 A;  5C8Q B;  3S3Z A;  4J4C A;  3GXZ A;  4J4E A;  5C8O A;  2EZN A;  1L5B A;  5C8P A;  2EZM A;  2KJL A;  2YHH A;  3HNX A; 
#chains in the Genus database with same CATH homology
 2RP3 A;  3HNU X;  3EZM A;  4J4F A;  2L2F A;  2RDK A;  3GXY A;  1J4V A;  3HP8 A;  2JZK A;  2Y1S A;  1LOM A;  2L9Y A;  3S3Y A;  2JZJ A;  3LHC A;  3CZZ A;  2PYS A;  1L5E A;  2JZL A;  1IIY A;  1N02 A;  2Z21 A;  5C8Q B;  3S3Z A;  4J4C A;  3GXZ A;  4J4E A;  5C8O A;  2EZN A;  1L5B A;  5C8P A;  2EZM A;  2KJL A;  2YHH A;  3HNX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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