2Z9AA

Crystal structure of human saposin c dimer in open conformation
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
77
structure length
77
Chain Sequence
DVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lipid binding protein
molecule keywords Proactivator polypeptide
publication title Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
pubmed doi rcsb
source organism Homo sapiens
total genus 26
structure length 77
sequence length 77
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03489 SapB_2 Saposin-like type B, region 2
A PF05184 SapB_1 Saposin-like type B, region 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.225.10 Mainly Alpha Orthogonal Bundle NK-Lysin Saposin-like 2z9aA00
1QDMA 2W51A 2RQYA 2DOBA 1N69A 2Z9AA 2GTGA 4UEXA 1L9LA 3S64A 4V2OA 3BQQA 3RFIA 4DDJA 3S63A 2R0RA 2QYPA 2RB3A 1SN6A 1OF9A 2R1QA 2W50A 3BQPA 4BITA 2KVDA 1M12A 1NKLA 2JS9A 2LPNA 2JSAA
chains in the Genus database with same CATH superfamily
1QDMA 2W51A 2RQYA 2DOBA 1N69A 2Z9AA 2GTGA 4UEXA 1L9LA 2JQ3A 3S64A 4V2OA 3EUKE 3BQQA 3RFIA 4DDJA 3EUJB 3CJLA 3S63A 2R0RA 2QYPA 2RB3A 1SN6A 1OF9A 2R1QA 2W50A 3BQPA 4BITA 2KVDA 1M12A 1NKLA 2JS9A 2LPNA 2JSAA
chains in the Genus database with same CATH topology
1QDMA 2W51A 2RQYA 2DOBA 1N69A 2Z9AA 2GTGA 4UEXA 1L9LA 3S64A 4V2OA 3BQQA 3RFIA 4DDJA 3S63A 2R0RA 2QYPA 2RB3A 1SN6A 1OF9A 2R1QA 2W50A 3BQPA 4BITA 2KVDA 1M12A 1NKLA 2JS9A 2LPNA 2JSAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QDM A;  2W51 A;  2RQY A;  2DOB A;  1N69 A;  2Z9A A;  2GTG A;  4UEX A;  1L9L A;  3S64 A;  4V2O A;  3BQQ A;  3RFI A;  4DDJ A;  3S63 A;  2R0R A;  2QYP A;  2RB3 A;  1SN6 A;  1OF9 A;  2R1Q A;  2W50 A;  3BQP A;  4BIT A;  2KVD A;  1M12 A;  1NKL A;  2JS9 A;  2LPN A;  2JSA A; 
#chains in the Genus database with same CATH topology
 1QDM A;  2W51 A;  2RQY A;  2DOB A;  1N69 A;  2Z9A A;  2GTG A;  4UEX A;  1L9L A;  2JQ3 A;  3S64 A;  4V2O A;  3EUK E;  3BQQ A;  3RFI A;  4DDJ A;  3EUJ B;  3CJL A;  3S63 A;  2R0R A;  2QYP A;  2RB3 A;  1SN6 A;  1OF9 A;  2R1Q A;  2W50 A;  3BQP A;  4BIT A;  2KVD A;  1M12 A;  1NKL A;  2JS9 A;  2LPN A;  2JSA A; 
#chains in the Genus database with same CATH homology
 1QDM A;  2W51 A;  2RQY A;  2DOB A;  1N69 A;  2Z9A A;  2GTG A;  4UEX A;  1L9L A;  3S64 A;  4V2O A;  3BQQ A;  3RFI A;  4DDJ A;  3S63 A;  2R0R A;  2QYP A;  2RB3 A;  1SN6 A;  1OF9 A;  2R1Q A;  2W50 A;  3BQP A;  4BIT A;  2KVD A;  1M12 A;  1NKL A;  2JS9 A;  2LPN A;  2JSA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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