3TBJA

The 1.7a crystal structure of actibind a t2 ribonucleases as antitumorigenic agents
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
237
structure length
237
Chain Sequence
TIDTCSSDSPLSCQTDNEASCCFNSPGGSLLQTQFWDYDPSDGPSDSWTIHGLWPDNCDGTYQEYCDESREYSNITSILEAQNRTELLSYMKEYWPDYEGADEDESFWEHEWNKHGTCINTIEPSCYTDYYAQEEVGDFFQQVVDLFKTLDSYTALSDAGITPSEDATYKLSDIEDALAAIHDGYPPYVGCEDGALSQLYYYFNVKGSAIGGTYVASERLEDSNCKDSGIKYPPKYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Actibind
publication title The 1.8 A crystal structure of ACTIBIND suggests a mode of action for T2 ribonucleases as antitumorigenic agents.
pubmed doi rcsb
total genus 74
structure length 237
sequence length 237
ec nomenclature
pdb deposition date 2011-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00445 Ribonuclease_T2 Ribonuclease T2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.730.10 Alpha Beta Alpha-Beta Complex Ribonuclease Rh; Chain A Ribonuclease T2-like 3tbjA00
4DW4A 4DW3A 1J1FA 4DVKA 4DVNA 1SGLA 2Z70A 1V9HA 2EA1A 1JY5A 1J1GA 1BK7A 1UCCA 3T0OA 2PQXA 3D3ZA 4DVLA 4DW5A 4DWAA 1VD1A 3TBJA 1BOLA 1IOOA 1VD3A 1DIXA 4DW7A 1VCZA 1IYBA 1UCGA 1UCAA 1UCDA 2PQYA 4DWCA 1IQQA
chains in the Genus database with same CATH superfamily
4DW4A 4DW3A 1J1FA 4DVKA 4DVNA 1SGLA 2Z70A 1V9HA 2EA1A 1JY5A 1J1GA 1BK7A 1UCCA 3T0OA 2PQXA 3D3ZA 4DVLA 4DW5A 4DWAA 1VD1A 3TBJA 1BOLA 1IOOA 1VD3A 1DIXA 4DW7A 1VCZA 1IYBA 1UCGA 1UCAA 1UCDA 2PQYA 4DWCA 1IQQA
chains in the Genus database with same CATH topology
4DW4A 4DW3A 1J1FA 4DVKA 4DVNA 1SGLA 2Z70A 1V9HA 2EA1A 1JY5A 1J1GA 1BK7A 1UCCA 3T0OA 2PQXA 3D3ZA 4DVLA 4DW5A 4DWAA 1VD1A 3TBJA 1BOLA 1IOOA 1VD3A 1DIXA 4DW7A 1VCZA 1IYBA 1UCGA 1UCAA 1UCDA 2PQYA 4DWCA 1IQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DW4 A;  4DW3 A;  1J1F A;  4DVK A;  4DVN A;  1SGL A;  2Z70 A;  1V9H A;  2EA1 A;  1JY5 A;  1J1G A;  1BK7 A;  1UCC A;  3T0O A;  2PQX A;  3D3Z A;  4DVL A;  4DW5 A;  4DWA A;  1VD1 A;  3TBJ A;  1BOL A;  1IOO A;  1VD3 A;  1DIX A;  4DW7 A;  1VCZ A;  1IYB A;  1UCG A;  1UCA A;  1UCD A;  2PQY A;  4DWC A;  1IQQ A; 
#chains in the Genus database with same CATH topology
 4DW4 A;  4DW3 A;  1J1F A;  4DVK A;  4DVN A;  1SGL A;  2Z70 A;  1V9H A;  2EA1 A;  1JY5 A;  1J1G A;  1BK7 A;  1UCC A;  3T0O A;  2PQX A;  3D3Z A;  4DVL A;  4DW5 A;  4DWA A;  1VD1 A;  3TBJ A;  1BOL A;  1IOO A;  1VD3 A;  1DIX A;  4DW7 A;  1VCZ A;  1IYB A;  1UCG A;  1UCA A;  1UCD A;  2PQY A;  4DWC A;  1IQQ A; 
#chains in the Genus database with same CATH homology
 4DW4 A;  4DW3 A;  1J1F A;  4DVK A;  4DVN A;  1SGL A;  2Z70 A;  1V9H A;  2EA1 A;  1JY5 A;  1J1G A;  1BK7 A;  1UCC A;  3T0O A;  2PQX A;  3D3Z A;  4DVL A;  4DW5 A;  4DWA A;  1VD1 A;  3TBJ A;  1BOL A;  1IOO A;  1VD3 A;  1DIX A;  4DW7 A;  1VCZ A;  1IYB A;  1UCG A;  1UCA A;  1UCD A;  2PQY A;  4DWC A;  1IQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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