4EDKA

The structure of the s. aureus dnag rna polymerase domain bound to gtp and manganese
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA primase
publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 115
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edkA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edkA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edkA01
4EDRA 2V1CA 4E2KA 1D3YA 1VDDA 4JCVA 1DD9A 4EE1A 3VE5A 4O6OA 1EQNA 3B39A 1T6T1 3VDPA 1DDEA 4O6PB 3VDUA 5GUJA 2Q2EA 4EDKA 2ZBKA 2AU3A 4EDTA 4EDVA 4EDGA
chains in the Genus database with same CATH superfamily
4EDRA 2V1CA 4E2KA 1D3YA 1VDDA 4JCVA 2ERLA 1DD9A 4EE1A 1ERCA 3VE5A 4O6OA 1EQNA 3B39A 3CU7A 2NSVA 1T6T1 3VDPA 1DDEA 4O6PB 3KXRA 2FCJA 2NSWA 3VDUA 2LMKA 5GUJA 2KK2A 2Q2EA 4EDKA 2I5RA 2KC6A 2ZBKA 3KLSA 2AU3A 2B39A 2JMSA 4EDTA 4EDVA 4EDGA
chains in the Genus database with same CATH topology
4EDRA 2V1CA 4E2KA 1D3YA 1VDDA 4JCVA 2ERLA 1DD9A 4EE1A 1ERCA 3VE5A 4O6OA 1EQNA 3B39A 3CU7A 2NSVA 1T6T1 3VDPA 1DDEA 4O6PB 3KXRA 2NSWA 3VDUA 2LMKA 5GUJA 2KK2A 2Q2EA 4EDKA 2KC6A 2ZBKA 3KLSA 2AU3A 2B39A 2JMSA 4EDTA 4EDVA 4EDGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EDR A;  2V1C A;  4E2K A;  1D3Y A;  1VDD A;  4JCV A;  1DD9 A;  4EE1 A;  3VE5 A;  4O6O A;  1EQN A;  3B39 A;  1T6T 1;  3VDP A;  1DDE A;  4O6P B;  3VDU A;  5GUJ A;  2Q2E A;  4EDK A;  2ZBK A;  2AU3 A;  4EDT A;  4EDV A;  4EDG A; 
#chains in the Genus database with same CATH topology
 4EDR A;  2V1C A;  4E2K A;  1D3Y A;  1VDD A;  4JCV A;  2ERL A;  1DD9 A;  4EE1 A;  1ERC A;  3VE5 A;  4O6O A;  1EQN A;  3B39 A;  3CU7 A;  2NSV A;  1T6T 1;  3VDP A;  1DDE A;  4O6P B;  3KXR A;  2FCJ A;  2NSW A;  3VDU A;  2LMK A;  5GUJ A;  2KK2 A;  2Q2E A;  4EDK A;  2I5R A;  2KC6 A;  2ZBK A;  3KLS A;  2AU3 A;  2B39 A;  2JMS A;  4EDT A;  4EDV A;  4EDG A; 
#chains in the Genus database with same CATH homology
 4EDR A;  2V1C A;  4E2K A;  1D3Y A;  1VDD A;  4JCV A;  2ERL A;  1DD9 A;  4EE1 A;  1ERC A;  3VE5 A;  4O6O A;  1EQN A;  3B39 A;  3CU7 A;  2NSV A;  1T6T 1;  3VDP A;  1DDE A;  4O6P B;  3KXR A;  2NSW A;  3VDU A;  2LMK A;  5GUJ A;  2KK2 A;  2Q2E A;  4EDK A;  2KC6 A;  2ZBK A;  3KLS A;  2AU3 A;  2B39 A;  2JMS A;  4EDT A;  4EDV A;  4EDG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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