4FXED

Crystal structure of the intact e. coli relbe toxin-antitoxin complex
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
78
structure length
71
Chain Sequence
YFLDFDERALKEWRKREQLKKKLVEVLESPRIEANKLRGMPDCYKIRSSGYRLVYQVIDEKVVVFVISVGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/toxin inhibitor
molecule keywords Antitoxin RelB
publication title The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
pubmed doi rcsb
source organism Escherichia coli
total genus 19
structure length 71
sequence length 78
chains with identical sequence E, F
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 4fxeD00
3G5OB 2KHEA 3OEIC 4PX8A 5CZEB 5IWHA 2OTRA 2A6SA 5CZFC 4Q2UB 2KC8A 4MMJA 4FXED 1WMIA 4LTTA 4MCXB 4ML0B 2A6QE 3BPQB 4LS4A 4NRNA 4MCTB 2A6RA 4YY3Y 3KXEA 5CW7B 4LSYA 1Z8MA 2KC9A 4ML2A 5CEGB 5IXLA 4MMGA 4FXHA 4FXIA
chains in the Genus database with same CATH superfamily
3G5OB 2KHEA 3OEIC 4PX8A 5CZEB 2DJHA 5IWHA 3VJ7A 4FBDA 2OTRA 2A6SA 5CZFC 4Q2UB 2KC8A 4MMJA 4FXED 1WMIA 4LTTA 4MCXB 4ML0B 2A6QE 3BPQB 4LS4A 2A8KA 4NRNA 4MCTB 2A6RA 4FXHA 3HI2B 2DFXE 2FHZB 1XQBA 4YY3Y 3KXEA 5CW7B 2PD0A 4LSYA 1Z8MA 4ML2A 5CEGB 5IXLA 4MMGA 2KC9A 4FXIA 3AO9A
chains in the Genus database with same CATH topology
3G5OB 2KHEA 3OEIC 4PX8A 5CZEB 5IWHA 2OTRA 2A6SA 5CZFC 4Q2UB 2KC8A 4MMJA 4FXED 1WMIA 4LTTA 4MCXB 4ML0B 2A6QE 3BPQB 4LS4A 4NRNA 4MCTB 2A6RA 4YY3Y 3KXEA 5CW7B 4LSYA 1Z8MA 2KC9A 4ML2A 5CEGB 5IXLA 4MMGA 4FXHA 4FXIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G5O B;  2KHE A;  3OEI C;  4PX8 A;  5CZE B;  5IWH A;  2OTR A;  2A6S A;  5CZF C;  4Q2U B;  2KC8 A;  4MMJ A;  4FXE D;  1WMI A;  4LTT A;  4MCX B;  4ML0 B;  2A6Q E;  3BPQ B;  4LS4 A;  4NRN A;  4MCT B;  2A6R A;  4YY3 Y;  3KXE A;  5CW7 B;  4LSY A;  1Z8M A;  2KC9 A;  4ML2 A;  5CEG B;  5IXL A;  4MMG A;  4FXH A;  4FXI A; 
#chains in the Genus database with same CATH topology
 3G5O B;  2KHE A;  3OEI C;  4PX8 A;  5CZE B;  2DJH A;  5IWH A;  3VJ7 A;  4FBD A;  2OTR A;  2A6S A;  5CZF C;  4Q2U B;  2KC8 A;  4MMJ A;  4FXE D;  1WMI A;  4LTT A;  4MCX B;  4ML0 B;  2A6Q E;  3BPQ B;  4LS4 A;  2A8K A;  4NRN A;  4MCT B;  2A6R A;  4FXH A;  3HI2 B;  2DFX E;  2FHZ B;  1XQB A;  4YY3 Y;  3KXE A;  5CW7 B;  2PD0 A;  4LSY A;  1Z8M A;  4ML2 A;  5CEG B;  5IXL A;  4MMG A;  2KC9 A;  4FXI A;  3AO9 A; 
#chains in the Genus database with same CATH homology
 3G5O B;  2KHE A;  3OEI C;  4PX8 A;  5CZE B;  5IWH A;  2OTR A;  2A6S A;  5CZF C;  4Q2U B;  2KC8 A;  4MMJ A;  4FXE D;  1WMI A;  4LTT A;  4MCX B;  4ML0 B;  2A6Q E;  3BPQ B;  4LS4 A;  4NRN A;  4MCT B;  2A6R A;  4YY3 Y;  3KXE A;  5CW7 B;  4LSY A;  1Z8M A;  2KC9 A;  4ML2 A;  5CEG B;  5IXL A;  4MMG A;  4FXH A;  4FXI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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