4FXHA

Crystal structure of the isolated e. coli rele toxin, p212121 form
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
94
structure length
87
Chain Sequence
AYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDYKIKRLVYQVIDEKVVVFVISVGKAERSEVYSEAVKRIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords mRNA interferase RelE
publication title The crystal structure of the intact E. coli RelBE toxin-antitoxin complex provides the structural basis for conditional cooperativity.
pubmed doi rcsb
source organism Escherichia coli
total genus 26
structure length 87
sequence length 94
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05016 ParE_toxin ParE toxin of type II toxin-antitoxin system, parDE
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2310.20 Alpha Beta 2-Layer Sandwich YaeB-like fold RelE-like 4fxhA00
4FXHA 5CZFC 4PX8A 3G5OB 4ML2A 5IWHA 2KHEA 1Z8MA 4MCTB 5CEGB 2KC9A 4NRNA 2A6QE 2KC8A 4MCXB 4ML0B 4FXIA 4MMGA 2A6RA 4Q2UB 2A6SA 4LS4A 4YY3Y 4LTTA 5CZEB 1WMIA 4MMJA 5CW7B 4LSYA 2OTRA 5IXLA 3OEIC 3BPQB 4FXED 3KXEA
chains in the Genus database with same CATH superfamily
4FXHA 5CZFC 2A8KA 4PX8A 3G5OB 4FBDA 4ML2A 5IWHA 2KHEA 1Z8MA 4MCTB 2DJHA 2KC9A 5CEGB 4NRNA 2A6QE 2KC8A 3HI2B 4MCXB 4FXIA 4ML0B 4MMGA 2A6RA 2DFXE 1XQBA 4Q2UB 2A6SA 4LS4A 4YY3Y 4LTTA 3AO9A 5CZEB 2FHZB 1WMIA 4MMJA 5CW7B 4LSYA 2OTRA 5IXLA 3OEIC 4FXED 3BPQB 2PD0A 3KXEA 3VJ7A
chains in the Genus database with same CATH topology
4FXHA 5CZFC 4PX8A 3G5OB 4ML2A 5IWHA 2KHEA 1Z8MA 4MCTB 5CEGB 2KC9A 4NRNA 2A6QE 2KC8A 4MCXB 4ML0B 4FXIA 4MMGA 2A6RA 4Q2UB 2A6SA 4LS4A 4YY3Y 4LTTA 5CZEB 1WMIA 4MMJA 5CW7B 4LSYA 2OTRA 5IXLA 3OEIC 3BPQB 4FXED 3KXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FXH A;  5CZF C;  4PX8 A;  3G5O B;  4ML2 A;  5IWH A;  2KHE A;  1Z8M A;  4MCT B;  5CEG B;  2KC9 A;  4NRN A;  2A6Q E;  2KC8 A;  4MCX B;  4ML0 B;  4FXI A;  4MMG A;  2A6R A;  4Q2U B;  2A6S A;  4LS4 A;  4YY3 Y;  4LTT A;  5CZE B;  1WMI A;  4MMJ A;  5CW7 B;  4LSY A;  2OTR A;  5IXL A;  3OEI C;  3BPQ B;  4FXE D;  3KXE A; 
#chains in the Genus database with same CATH topology
 4FXH A;  5CZF C;  2A8K A;  4PX8 A;  3G5O B;  4FBD A;  4ML2 A;  5IWH A;  2KHE A;  1Z8M A;  4MCT B;  2DJH A;  2KC9 A;  5CEG B;  4NRN A;  2A6Q E;  2KC8 A;  3HI2 B;  4MCX B;  4FXI A;  4ML0 B;  4MMG A;  2A6R A;  2DFX E;  1XQB A;  4Q2U B;  2A6S A;  4LS4 A;  4YY3 Y;  4LTT A;  3AO9 A;  5CZE B;  2FHZ B;  1WMI A;  4MMJ A;  5CW7 B;  4LSY A;  2OTR A;  5IXL A;  3OEI C;  4FXE D;  3BPQ B;  2PD0 A;  3KXE A;  3VJ7 A; 
#chains in the Genus database with same CATH homology
 4FXH A;  5CZF C;  4PX8 A;  3G5O B;  4ML2 A;  5IWH A;  2KHE A;  1Z8M A;  4MCT B;  5CEG B;  2KC9 A;  4NRN A;  2A6Q E;  2KC8 A;  4MCX B;  4ML0 B;  4FXI A;  4MMG A;  2A6R A;  4Q2U B;  2A6S A;  4LS4 A;  4YY3 Y;  4LTT A;  5CZE B;  1WMI A;  4MMJ A;  5CW7 B;  4LSY A;  2OTR A;  5IXL A;  3OEI C;  3BPQ B;  4FXE D;  3KXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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