4I6OA

Crystal structure of chemically synthesized human anaphylatoxin c3a
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
68
structure length
68
Chain Sequence
DKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords Complement C3
publication title Efficient chemical synthesis of human complement protein C3a.
pubmed doi rcsb
total genus 22
structure length 68
sequence length 68
ec nomenclature
pdb deposition date 2012-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4i6oA00
1KJSA 4P39A 2A73B 3KLSA 3HQBA 4P3AA 4WB3A 4WB2A 4FXKB 2B39A 4UU9C 5B4PB 3CU7A 5JPNB 4HWJA 1CFAA 3HQAA 4P3BA 4I6OA 1C5AA 4HW5A
chains in the Genus database with same CATH superfamily
1KJSA 4P39A 2A73B 3VDXA 3KLSA 4PUSA 1EA3A 3HQBA 4ITVA 4P3AA 4D9JA 4WB3A 4WB2A 1AA7A 5CQEA 4FXKB 3MD2A 2B39A 4IQ4A 4FXGB 4UU9C 5B4PB 3CU7A 5JPNB 4HWJA 5JPMB 1CFAA 3HQAA 2Z16A 4P3BA 4I6OA 1C5AA 4HW5A
chains in the Genus database with same CATH topology
1KJSA 4P39A 2A73B 3KLSA 3HQBA 4P3AA 4WB3A 4WB2A 4FXKB 2B39A 4UU9C 5B4PB 3CU7A 5JPNB 4HWJA 1CFAA 3HQAA 4P3BA 4I6OA 1C5AA 4HW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KJS A;  4P39 A;  2A73 B;  3KLS A;  3HQB A;  4P3A A;  4WB3 A;  4WB2 A;  4FXK B;  2B39 A;  4UU9 C;  5B4P B;  3CU7 A;  5JPN B;  4HWJ A;  1CFA A;  3HQA A;  4P3B A;  4I6O A;  1C5A A;  4HW5 A; 
#chains in the Genus database with same CATH topology
 1KJS A;  4P39 A;  2A73 B;  3VDX A;  3KLS A;  4PUS A;  1EA3 A;  3HQB A;  4ITV A;  4P3A A;  4D9J A;  4WB3 A;  4WB2 A;  1AA7 A;  5CQE A;  4FXK B;  3MD2 A;  2B39 A;  4IQ4 A;  4FXG B;  4UU9 C;  5B4P B;  3CU7 A;  5JPN B;  4HWJ A;  5JPM B;  1CFA A;  3HQA A;  2Z16 A;  4P3B A;  4I6O A;  1C5A A;  4HW5 A; 
#chains in the Genus database with same CATH homology
 1KJS A;  4P39 A;  2A73 B;  3KLS A;  3HQB A;  4P3A A;  4WB3 A;  4WB2 A;  4FXK B;  2B39 A;  4UU9 C;  5B4P B;  3CU7 A;  5JPN B;  4HWJ A;  1CFA A;  3HQA A;  4P3B A;  4I6O A;  1C5A A;  4HW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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