5FWWC

Wnt modulator kremen in complex with dkk1 (crd2) and lrp6 (pe3pe4)
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
85
structure length
76
Chain Sequence
KGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKRLHTCQRH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6
publication title Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
pubmed doi rcsb
source organism Homo sapiens
total genus 15
structure length 76
sequence length 85
ec nomenclature
pdb deposition date 2016-02-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.80.10 Mainly Beta Ribbon Lipase, subunit A Lipase, subunit A 5fwwC00
1IMTA 2N8KA 2KRAA 2JTKA 5FWWC 1PCNA 1N8SC 1PCOA 1ETHB 3S2KC 1LPAA 1LPBA 3S8VX
chains in the Genus database with same CATH superfamily
1IMTA 2N8KA 2KRAA 2JTKA 3BT4A 1PCNA 5FWWC 1N8SC 1PCOA 1ETHB 3S2KC 1LPAA 1LPBA 3S8VX
chains in the Genus database with same CATH topology
1IMTA 2N8KA 2KRAA 2JTKA 3BT4A 1PCNA 5FWWC 1N8SC 1PCOA 1ETHB 3S2KC 1LPAA 1LPBA 3S8VX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IMT A;  2N8K A;  2KRA A;  2JTK A;  5FWW C;  1PCN A;  1N8S C;  1PCO A;  1ETH B;  3S2K C;  1LPA A;  1LPB A;  3S8V X; 
#chains in the Genus database with same CATH topology
 1IMT A;  2N8K A;  2KRA A;  2JTK A;  3BT4 A;  1PCN A;  5FWW C;  1N8S C;  1PCO A;  1ETH B;  3S2K C;  1LPA A;  1LPB A;  3S8V X; 
#chains in the Genus database with same CATH homology
 1IMT A;  2N8K A;  2KRA A;  2JTK A;  3BT4 A;  1PCN A;  5FWW C;  1N8S C;  1PCO A;  1ETH B;  3S2K C;  1LPA A;  1LPB A;  3S8V X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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