134
|
332
|
4lm1A |
Crystal structure of pde10a2 with fragment zt450 |
134
|
330
|
4msnA |
Crystal structure of pde10a2 with fragment zt0451 (8-nitroquinoline) |
135
|
330
|
4ms0A |
Crystal structure of pde10a2 with fragment zt0443 (6-chloropyrimidine-2,4-diamine) |
136
|
330
|
4llkA |
Crystal structure of pde10a2 with fragment zt217 |
136
|
331
|
4lm3A |
Crystal structure of pde10a2 with fragment zt464 |
132
|
328
|
4mscA |
Crystal structure of pde10a2 with fragment zt1595 (2-[(quinolin-7-yloxy)methyl]quinoline) |
136
|
330
|
4msaA |
Crystal structure of pde10a2 with fragment zt0449 (5-nitro-1h-benzimidazole) |
118
|
326
|
4md6A |
Crystal structure of pde5 in complex with inhibitor 5r |
136
|
330
|
4lkqA |
Crystal structure of pde10a2 with fragment zt017 |
135
|
330
|
4llpA |
Crystal structure of pde10a2 with fragment zt401 |
128
|
318
|
4muwA |
Crystal structure of pde10a with novel keto-benzimidazole inhibitor |
138
|
330
|
4mrzA |
Crystal structure of pde10a2 with fragment zt0429 (4-methyl-3-nitropyridin-2-amine) |
133
|
329
|
4lljA |
Crystal structure of pde10a2 with fragment zt214 |
136
|
330
|
4lm2A |
Crystal structure of pde10a2 with fragment zt462 |
120
|
324
|
4i9zA |
Crystal structure of the pde5a1 catalytic domain in complex with novel inhibitors |
120
|
324
|
4ia0A |
Crystal structure of the pde5a1 catalytic domain in complex with novel inhibitors |
130
|
318
|
4heuA |
Crystal structure of pde10a with a biaryl ether inhibitor ((1-(3-(4-((1h-benzo[d]imidazol-2-yl)amino)phenoxy)pyridin-2-yl)piperidin-4-yl)methanol) |
129
|
318
|
4hf4A |
Crystal structure of pde10a with a biaryl ether inhibitor (1-(1-(3-(4-(benzo[d]thiazol-2-ylamino)phenoxy)pyrazin-2-yl)piperidin-4-yl)ethanol) |
124
|
322
|
4g2wA |
Crystal structure of pde5a in complex with its inhibitor |
133
|
326
|
4gh6A |
Crystal structure of the pde9a catalytic domain in complex with inhibitor 28 |
119
|
325
|
4g2yA |
Crystal structure of pde5a complexed with its inhibitor |
137
|
328
|
4g2lA |
Human pde9 in complex with selective compound |
128
|
328
|
4g2jA |
Human pde9 in complex with selective compound |
130
|
322
|
4fcbA |
Potent and selective phosphodiesterase 10a inhibitors |
132
|
322
|
4fcdA |
Potent and selective phosphodiesterase 10a inhibitors |
130
|
305
|
3qpoA |
Structure of pde10-inhibitor complex |
127
|
305
|
3qpnA |
Structure of pde10-inhibitor complex |
126
|
305
|
3qppA |
Structure of pde10-inhibitor complex |
137
|
325
|
3qi3A |
Crystal structure of pde9a(q453e) in complex with inhibitor bay73-6691 |
138
|
325
|
3qi4A |
Crystal structure of pde9a(q453e) in complex with ibmx |
131
|
326
|
3n3zA |
Crystal structure of pde9a (e406a) mutant in complex with ibmx |
101
|
418
|
3mf0A |
Crystal structure of pde5a gaf domain (89-518) |
126
|
308
|
3lxgA |
Crystal structure of rat phosphodiesterase 10a in complex with ligand web-3 |
104
|
431
|
3lfvA |
Crystal structure of unliganded pde5a gaf domain |
133
|
324
|
3jwqA |
Crystal structure of chimeric pde5/pde6 catalytic domain complexed with sildenafil |
134
|
320
|
3k3hA |
Crystal structure of the pde9a catalytic domain in complex with (s)-bay73-6691 |
2
|
17
|
3jwrC |
Crystal structure of chimeric pde5/pde6 catalytic domain complexed with 3-isobutyl-1-methylxanthine (ibmx) and pde6 gamma-subunit inhibitory peptide 70-87. |
131
|
323
|
3jwrA |
Crystal structure of chimeric pde5/pde6 catalytic domain complexed with 3-isobutyl-1-methylxanthine (ibmx) and pde6 gamma-subunit inhibitory peptide 70-87. |
134
|
319
|
3k3eA |
Crystal structure of the pde9a catalytic domain in complex with (r)-bay73-6691 |
2
|
17
|
3jabD |
Domain organization and conformational plasticity of the g protein effector, pde6 |
106
|
328
|
3jbqB |
Domain organization and conformational plasticity of the g protein effector, pde6 |
134
|
328
|
3jswA |
Human pde9 in complex with selective inhibitor |
134
|
328
|
3jabC |
Domain organization and conformational plasticity of the g protein effector, pde6 |
1
|
17
|
3jbqD |
Domain organization and conformational plasticity of the g protein effector, pde6 |
128
|
328
|
3jsiA |
Human phosphodiesterase 9 in complex with inhibitor |
38
|
171
|
3jbq1 |
Domain organization and conformational plasticity of the g protein effector, pde6 |
128
|
305
|
3hqyA |
Discovery of novel inhibitors of pde10a |
128
|
305
|
3hqzA |
Discovery of novel inhibitors of pde10a |
130
|
303
|
3hqwA |
Discovery of novel inhibitors of pde10a |
128
|
305
|
3hr1A |
Discovery of novel inhibitors of pde10a |