1G1FA

Crystal structure of protein tyrosine phosphatase 1b complexed with a tri-phosphorylated peptide (rdi(ptr)etd(ptr)(ptr)rk) from the insulin receptor kinase
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase, signaling protein
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
publication title Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
pubmed doi rcsb
source organism Homo sapiens
total genus 98
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g1fA00
1YGRA 1NNYA 1C88A 1G4WR 4HRFA 3CWEA 2OOQA 4GS0A 1U24A 3ZM3A 4OHLA 4QUNA 4RH5A 2F6FA 4QAHA 4Y14A 1MKPA 4H1OA 3QKPA 1XBOA 5BZZA 1PA9A 4H34A 1C85A 1G4US 5KA9A 1I9SA 2R0BA 1L8GA 3ZMQA 5I6VA 1OETA 1OEVA 2PSZA 1OHCA 1LARA 4HJPA 2I6PA 2OZ5A 4GWFA 3S4EA 1YN9A 1FPRA 5K24A 1JF7A 2F71A 4NYHA 1C84A 4HJQA 1LQFA 4KYRA 4RHGA 4GFVA 1OEOX 2QDCA 2I6JA 2J17A 2HY3A 1PYNA 3F9BA 1PXHA 1WRMA 2HC2A 1PTYA 2AHSA 2HVLA 1Q6SA 3ZM0A 4WU3A 3BRHA 2RF6A 2HC1A 2H4VA 3QCGA 1XRIA 5KABA 1Q6NA 1LYVA 4TVVA 2VEUA 1AAXA 1RPMA 1T48A 1YTSA 2CM7A 2CJZA 1OHDA 5MMZB 2CFVA 1OHEA 2M3VA 2QEPA 4MBBA 4D3QA 2PT0A 1YFOA 4RI5A 3LJ8A 3BM8A 3F9AA 1Q6PA 2Y96A 3QCNA 4NWGA 5KA1A 1PA1A 2VEWA 3D1HA 4JMKA 3QCHA 4QUMA 1R6HA 3O5XA 3I80A 5K25A 1XXPA 2F46A 4R0SA 2I6IA 3D9CA 4RDDA 1PTTA 2GWOA 4GE6A 1BZCA 2B3OA 1G1FA 3RGOA 2Q47A 4RI4A 4R0TA 1A5YA 4RKKA 1YZ4A 5GTJA 5KADA 3D44A 5BUGA 2I4GA 1FQ1A 2F6TA 2QBRA 2YDUA 3I36A 4OHIA 4GRZA 1C87A 1V3AA 3BLUA 3RZ2A 1ZCLA 2WGPA 5IBMA 2QCJA 3S3FA 2ESBA 2CM8A 2A8BA 1Q6MA 1X24A 2CM3A 1Q6JA 5EHRA 1D5RA 1OESA 3D1OA 3GXGA 5IBSA 3U96A 4WU2A 3S4OA 2DXPA 2PA5A 1PH0A 4ICZA 1BZHA 4GE2A 2AZRA 2CNEA 2HCMA 3V0EA 1NWEA 3A5KA 2HNPA 3F81A 2G59A 5K23A 3AWFA 2NTAA 4YR8B 2VEVA 3V0JA 1XXVA 1G7FA 1ZC0A 5EHPA 1T49A 3NMEA 4GRYA 2NV5A 3QCLA 2J16B 5KA3A 2OUDA 4QAPA 1J4XA 3EB1A 2I1YA 2CNFA 5J8RA 3B7OA 4IKCA 1T4JA 2G6ZA 2I3UA 2FH7A 1NO6A 3V0FA 2J16A 1BZJA 2HNQA 2NLKA 2Y2FA 4BJOA 2HB1A 2B4PA 3QCDA 2QDPA 4WOHA 3S3KA 1I9TA 2GJTA 2F6WA 1NZ7A 1GWZA 2FJMA 3O4SA 2GP0A 3AWEA 2F6ZA 4KYQA 3OMHA 3EU0A 2B07A 2I4EA 4ERCA 2CNHA 4D3RA 2HXPA 2CMAA 3ZM2A 1U26A 2I42A 2C46A 3QCKA 1KAVA 4JMJA 1P15A 4BPCA 3O4TA 2PI7A 5KA2A 5K22A 4GFUA 4PYHA 5BX1A 1PTUA 1YPTA 1Q1MA 2CMCA 4ZN5A 1PTVA 2B49A 5LXQB 3EAXA 2ZN7A 3PS5A 1WCHA 2P4DA 3V0HA 1JLNA 3H2XA 3A5JA 5HDEA 2VEYA 3SMEA 3OLRA 1XM2A 5KA7A 3O4UA 1QXKA 3ZM1A 2I3RA 3EZZA 2FJNA 4I8NA 4OHDA 3RGQA 5M43A 2H4GA 3N0AA 2I5XA 3D1QA 4GE5A 1GFYA 2SHPA 2BGDA 2NT2A 1EEOA 4AZ1A 2IMGA 2H02A 3F41A 2E0TA 3V0IA 3V0GA 2B4OA 4WTYA 4ZRTA 2CMBA 2I4HA 2F70A 2H04A 4ZI4A 3MMJA 4Y2EA 1NWLA 3AWGA 1YTWA 1ZCKA 2P6XA 2BZLA 3QCMA 3D42A 1WAXA 4Z6BA 1ONZA 2A3KA 2QBQA 2ZMMA 3QCCA 1L8KA 4QBWA 2QDMA 4D3PA 1G7GA 2F6VA 1G1GA 2CNGA 2NT7A 4QBEA 5KAAA 1YWFA 2BGEA 2C7SA 2H4KA 3SR9A 4OHHA 2Q05A 5KA4A 4KI9A 4JNBA 1VHRA 2OC3A 2MBCA 5BZXA 5K9WA 1C83A 3EMUA 1FPZA 3I7ZA 4OHEA 1G1HA 4YAAA 2I6MA 2NZ6A 3O3LA 1QZ0A 3ZV2A 2VEXA 4DGPA 1U25A 1Q6TA 2F6YA 2PBNA 2QCTA 1ZZWA 4RH9A 4NWFA 1ONYA 2I75A 4NNDA 4PVGA 3GXHA 5KACA 1KAKA 1NL9A 3CM3A 5AWXA 2B4UA 3QKQA 1YGUA 4J51A 2PQ5A 5K9VA 4S0GA 3QCEA 1OEUA 3BLTA 2QBSA 2JJDA 3MOWA 3QCFA 2H03A 1YTNA 3M4UA 2BIJA 4B04A 2BV5A 4R30A 3V0DA 2CNIA 1M3GA 4NX8A 1OEMX 3F99A 3S3HA 5KA0A 5KA8A 4DGXA 1I57A 4JBCA 3MOZA 1RXDA 3QCIA 3QCBA 3ZMPA 2CM2A 2I6OA 1SUGA 3QCJA 1ECVA 3S3EA 1C86A 1EENA 3RO1A 2B4SA 2QBPA
chains in the Genus database with same CATH superfamily
1YGRA 1NNYA 1C88A 1G4WR 4HRFA 3CWEA 2OOQA 4GS0A 1U24A 3ZM3A 4OHLA 4QUNA 4RH5A 2F6FA 4QAHA 4Y14A 1MKPA 4H1OA 4C13A 3QKPA 1XBOA 5BZZA 1PA9A 4H34A 1C85A 1G4US 5KA9A 1I9SA 2R0BA 2Y67A 1L8GA 4QDIA 3ZMQA 5I6VA 1OETA 1OEVA 2PSZA 1OHCA 1LARA 4HJPA 3UAGA 2I6PA 2OZ5A 5A5EA 4GWFA 3S4EA 1YN9A 2Y68A 2JFFA 1FPRA 5K24A 1JF7A 2F71A 4NYHA 1C84A 2VORA 4HJQA 1LQFA 4KYRA 4RHGA 4QF5A 4GFVA 1OEOX 1E8CA 2QDCA 2I6JA 2J17A 2HY3A 1PYNA 2JFHA 4HV4A 1PXHA 3F9BA 1WRMA 2HC2A 1PTYA 2AHSA 2HVLA 1Q6SA 3ZM0A 4WU3A 3BRHA 2RF6A 2HC1A 2H4VA 3QCGA 1XRIA 5KABA 1Q6NA 1LYVA 4TVVA 2VEUA 2XJAA 1AAXA 1RPMA 1T48A 1YTSA 2CM7A 2CJZA 1OHDA 5MMZB 2CFVA 1OHEA 2M3VA 2QEPA 4MBBA 4D3QA 2PT0A 2XPCA 1YFOA 4RI5A 3LJ8A 3BM8A 3F9AA 3LK7A 1Q6PA 2Y96A 3QCNA 2WJPA 4NWGA 5KA1A 1PA1A 2VEWA 3D1HA 4JMKA 3QCHA 4QUMA 1R6HA 3O5XA 3I80A 5K25A 1XXPA 2F46A 2Y66A 4R0SA 2I6IA 3D9CA 4RDDA 1PTTA 2GWOA 4GE6A 1BZCA 2B3OA 1G1FA 3RGOA 3N2AA 2Q47A 4RI4A 4R0TA 1A5YA 4RKKA 1YZ4A 4ZIYA 5GTJA 5KADA 3D44A 5BUGA 2I4GA 1FQ1A 2F6TA 2QBRA 2UUOA 3ZM6A 2YDUA 3I36A 4OHIA 4GRZA 1C87A 1V3AA 3BLUA 2GC5A 3RZ2A 1ZCLA 2WGPA 5IBMA 2QCJA 3S3FA 2ESBA 2CM8A 2A8BA 3ZL8A 1Q6MA 1X24A 2CM3A 1Q6JA 1JBWA 5EHRA 1D5RA 1OESA 3D1OA 3GXGA 5IBSA 2UAGA 3U96A 4WU2A 3S4OA 2DXPA 2PA5A 1PH0A 4ICZA 1BZHA 4GE2A 2AZRA 2CNEA 2HCMA 3V0EA 1EEHA 1NWEA 3A5KA 2HNPA 3F81A 2G59A 1W7KA 1J6UA 5K23A 3AWFA 2NTAA 4YR8B 2VEVA 3V0JA 1XXVA 4C12A 1G7FA 1ZC0A 4CVLA 5EHPA 1GQYA 1T49A 1E0DA 3NMEA 4GRYA 2NV5A 3QCLA 2J16B 5KA3A 2OUDA 4QAPA 1J4XA 3EB1A 2I1YA 2CNFA 5J8RA 3B7OA 4IKCA 1T4JA 2G6ZA 2I3UA 2FH7A 1NO6A 3V0FA 2J16A 2AM1A 1BZJA 2HNQA 2NLKA 2Y2FA 4BJOA 2HB1A 2B4PA 3QCDA 2QDPA 3QCZA 4WOHA 3S3KA 1I9TA 1FGSA 2GJTA 2F6WA 1NZ7A 1GWZA 2FJMA 3O4SA 2GP0A 3AWEA 3HN7A 2F6ZA 4KYQA 3OMHA 3EU0A 2B07A 2I4EA 4ERCA 2CNHA 4D3RA 1W78A 2HXPA 2CMAA 3ZM2A 1U26A 2I42A 2C46A 3QCKA 1KAVA 4JMJA 1P15A 4BPCA 3O4TA 4UAGA 2PI7A 5KA2A 5K22A 4GFUA 4PYHA 5BX1A 1PTUA 1YPTA 3NRSA 1Q1MA 2F00A 2CMCA 5A5FA 4ZN5A 1PTVA 2B49A 1GQQA 5LXQB 3EAXA 2JFGA 2ZN7A 3PS5A 1WCHA 2AM2A 4CVMA 2P4DA 3V0HA 2VTDA 1JLNA 3H2XA 3A5JA 5HDEA 2VEYA 3SMEA 3OLRA 1XM2A 5KA7A 3O4UA 1QXKA 3ZM1A 4BUCA 2I3RA 3EZZA 2FJNA 4I8NA 3MVNA 4OHDA 3RGQA 5M43A 2H4GA 2VOSA 3N0AA 2I5XA 3D1QA 4GE5A 1GFYA 2SHPA 2BGDA 2NT2A 1EEOA 4AZ1A 2GC6A 2IMGA 2H02A 3F41A 2E0TA 3V0IA 3V0GA 2B4OA 4WTYA 4ZRTA 4BUBA 2CMBA 2I4HA 2F70A 2H04A 4ZI4A 3MMJA 4Y2EA 1NWLA 3AWGA 1YTWA 1ZCKA 2P6XA 2BZLA 3QCMA 3D42A 1WAXA 2Y1OA 4CVKA 4Z6BA 1ONZA 2A3KA 2QBQA 2ZMMA 2WTZA 3QCCA 1L8KA 4QBWA 2QDMA 4D3PA 1G7GA 1O5ZA 2F6VA 1G1GA 2CNGA 2NT7A 4QBEA 5KAAA 1YWFA 2BGEA 2C7SA 2H4KA 2VTEA 3SR9A 1GG4A 2X5OA 4OHHA 3PYZA 2Q05A 5KA4A 2GCAA 4KI9A 4JNBA 1VHRA 2OC3A 2MBCA 5BZXA 5K9WA 1C83A 3EMUA 1FPZA 3I7ZA 1JBVA 4OHEA 1G1HA 4YAAA 2I6MA 2NZ6A 3O3LA 1QZ0A 3ZV2A 2VEXA 4DGPA 1U25A 1Q6TA 2F6YA 2PBNA 2QCTA 1ZZWA 4RH9A 4NWFA 1ONYA 2I75A 1P3DA 4NNDA 4PVGA 3GXHA 5KACA 1KAKA 1NL9A 3CM3A 5AWXA 2B4UA 3QKQA 1YGUA 4J51A 2PQ5A 1P31A 5K9VA 4S0GA 3QCEA 1OEUA 3BLTA 2QBSA 3ZM5A 2GCBA 2JJDA 3MOWA 3QCFA 2H03A 1YTNA 3M4UA 2BIJA 4B04A 2BV5A 4R30A 3V0DA 2CNIA 1M3GA 4NX8A 1OEMX 3F99A 3S3HA 5KA0A 5KA8A 4DGXA 1I57A 4JBCA 3MOZA 1RXDA 1UAGA 2UUPA 3QCIA 3QCBA 3ZMPA 2CM2A 2I6OA 1SUGA 3QCJA 1ECVA 3S3EA 1C86A 1EENA 3RO1A 2B4SA 2QBPA
chains in the Genus database with same CATH topology
1YGRA 1NNYA 1C88A 1G4WR 4HRFA 3CWEA 2OOQA 4GS0A 1U24A 3ZM3A 4OHLA 4QUNA 4RH5A 2F6FA 4QAHA 4Y14A 1MKPA 4H1OA 3QKPA 1XBOA 5BZZA 1PA9A 4H34A 1C85A 1G4US 5KA9A 1I9SA 2R0BA 1L8GA 3ZMQA 5I6VA 1OETA 1OEVA 2PSZA 1OHCA 1LARA 4HJPA 2I6PA 2OZ5A 4GWFA 3S4EA 1YN9A 1FPRA 5K24A 1JF7A 2F71A 4NYHA 1C84A 4HJQA 1LQFA 4KYRA 4RHGA 4GFVA 1OEOX 2QDCA 2I6JA 2J17A 2HY3A 1PYNA 3F9BA 1PXHA 1WRMA 2HC2A 1PTYA 2AHSA 2HVLA 1Q6SA 3ZM0A 4WU3A 3BRHA 2RF6A 2HC1A 2H4VA 3QCGA 1XRIA 5KABA 1Q6NA 1LYVA 4TVVA 2VEUA 1AAXA 1RPMA 1T48A 1YTSA 2CM7A 2CJZA 1OHDA 5MMZB 2CFVA 1OHEA 2M3VA 2QEPA 4MBBA 4D3QA 2PT0A 1YFOA 4RI5A 3LJ8A 3BM8A 3F9AA 1Q6PA 2Y96A 3QCNA 4NWGA 5KA1A 1PA1A 2VEWA 3D1HA 4JMKA 3QCHA 4QUMA 1R6HA 3O5XA 3I80A 5K25A 1XXPA 2F46A 4R0SA 2I6IA 3D9CA 4RDDA 1PTTA 2GWOA 4GE6A 1BZCA 2B3OA 1G1FA 3RGOA 2Q47A 4RI4A 4R0TA 1A5YA 4RKKA 1YZ4A 5GTJA 5KADA 3D44A 5BUGA 2I4GA 1FQ1A 2F6TA 2QBRA 2YDUA 3I36A 4OHIA 4GRZA 1C87A 1V3AA 3BLUA 3RZ2A 1ZCLA 2WGPA 5IBMA 2QCJA 3S3FA 2ESBA 2CM8A 2A8BA 1Q6MA 1X24A 2CM3A 1Q6JA 5EHRA 1D5RA 1OESA 3D1OA 3GXGA 5IBSA 3U96A 4WU2A 3S4OA 2DXPA 2PA5A 1PH0A 4ICZA 1BZHA 4GE2A 2AZRA 2CNEA 2HCMA 3V0EA 1NWEA 3A5KA 2HNPA 3F81A 2G59A 5K23A 3AWFA 2NTAA 4YR8B 2VEVA 3V0JA 1XXVA 1G7FA 1ZC0A 5EHPA 1T49A 3NMEA 4GRYA 2NV5A 3QCLA 2J16B 5KA3A 2OUDA 4QAPA 1J4XA 3EB1A 2I1YA 2CNFA 5J8RA 3B7OA 4IKCA 1T4JA 2G6ZA 2I3UA 2FH7A 1NO6A 3V0FA 2J16A 1BZJA 2HNQA 2NLKA 2Y2FA 4BJOA 2HB1A 2B4PA 3QCDA 2QDPA 4WOHA 3S3KA 1I9TA 2GJTA 2F6WA 1NZ7A 1GWZA 2FJMA 3O4SA 2GP0A 3AWEA 2F6ZA 4KYQA 3OMHA 3EU0A 2B07A 2I4EA 4ERCA 2CNHA 4D3RA 2HXPA 2CMAA 3ZM2A 1U26A 2I42A 2C46A 3QCKA 1KAVA 4JMJA 1P15A 4BPCA 3O4TA 2PI7A 5KA2A 5K22A 4GFUA 4PYHA 5BX1A 1PTUA 1YPTA 1Q1MA 2CMCA 4ZN5A 1PTVA 2B49A 5LXQB 3EAXA 2ZN7A 3PS5A 1WCHA 2P4DA 3V0HA 1JLNA 3H2XA 3A5JA 5HDEA 2VEYA 3SMEA 3OLRA 1XM2A 5KA7A 3O4UA 1QXKA 3ZM1A 2I3RA 3EZZA 2FJNA 4I8NA 4OHDA 3RGQA 5M43A 2H4GA 3N0AA 2I5XA 3D1QA 4GE5A 1GFYA 2SHPA 2BGDA 2NT2A 1EEOA 4AZ1A 2IMGA 2H02A 3F41A 2E0TA 3V0IA 3V0GA 2B4OA 4WTYA 4ZRTA 2CMBA 2I4HA 2F70A 2H04A 4ZI4A 3MMJA 4Y2EA 1NWLA 3AWGA 1YTWA 1ZCKA 2P6XA 2BZLA 3QCMA 3D42A 1WAXA 4Z6BA 1ONZA 2A3KA 2QBQA 2ZMMA 3QCCA 1L8KA 4QBWA 2QDMA 4D3PA 1G7GA 2F6VA 1G1GA 2CNGA 2NT7A 4QBEA 5KAAA 1YWFA 2BGEA 2C7SA 2H4KA 3SR9A 4OHHA 2Q05A 5KA4A 4KI9A 4JNBA 1VHRA 2OC3A 2MBCA 5BZXA 5K9WA 1C83A 3EMUA 1FPZA 3I7ZA 4OHEA 1G1HA 4YAAA 2I6MA 2NZ6A 3O3LA 1QZ0A 3ZV2A 2VEXA 4DGPA 1U25A 1Q6TA 2F6YA 2PBNA 2QCTA 1ZZWA 4RH9A 4NWFA 1ONYA 2I75A 4NNDA 4PVGA 3GXHA 5KACA 1KAKA 1NL9A 3CM3A 5AWXA 2B4UA 3QKQA 1YGUA 4J51A 2PQ5A 5K9VA 4S0GA 3QCEA 1OEUA 3BLTA 2QBSA 2JJDA 3MOWA 3QCFA 2H03A 1YTNA 3M4UA 2BIJA 4B04A 2BV5A 4R30A 3V0DA 2CNIA 1M3GA 4NX8A 1OEMX 3F99A 3S3HA 5KA0A 5KA8A 4DGXA 1I57A 4JBCA 3MOZA 1RXDA 3QCIA 3QCBA 3ZMPA 2CM2A 2I6OA 1SUGA 3QCJA 1ECVA 3S3EA 1C86A 1EENA 3RO1A 2B4SA 2QBPA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1YGR A;  1NNY A;  1C88 A;  1G4W R;  4HRF A;  3CWE A;  2OOQ A;  4GS0 A;  1U24 A;  3ZM3 A;  4OHL A;  4QUN A;  4RH5 A;  2F6F A;  4QAH A;  4Y14 A;  1MKP A;  4H1O A;  3QKP A;  1XBO A;  5BZZ A;  1PA9 A;  4H34 A;  1C85 A;  1G4U S;  5KA9 A;  1I9S A;  2R0B A;  1L8G A;  3ZMQ A;  5I6V A;  1OET A;  1OEV A;  2PSZ A;  1OHC A;  1LAR A;  4HJP A;  2I6P A;  2OZ5 A;  4GWF A;  3S4E A;  1YN9 A;  1FPR A;  5K24 A;  1JF7 A;  2F71 A;  4NYH A;  1C84 A;  4HJQ A;  1LQF A;  4KYR A;  4RHG A;  4GFV A;  1OEO X;  2QDC A;  2I6J A;  2J17 A;  2HY3 A;  1PYN A;  3F9B A;  1PXH A;  1WRM A;  2HC2 A;  1PTY A;  2AHS A;  2HVL A;  1Q6S A;  3ZM0 A;  4WU3 A;  3BRH A;  2RF6 A;  2HC1 A;  2H4V A;  3QCG A;  1XRI A;  5KAB A;  1Q6N A;  1LYV A;  4TVV A;  2VEU A;  1AAX A;  1RPM A;  1T48 A;  1YTS A;  2CM7 A;  2CJZ A;  1OHD A;  5MMZ B;  2CFV A;  1OHE A;  2M3V A;  2QEP A;  4MBB A;  4D3Q A;  2PT0 A;  1YFO A;  4RI5 A;  3LJ8 A;  3BM8 A;  3F9A A;  1Q6P A;  2Y96 A;  3QCN A;  4NWG A;  5KA1 A;  1PA1 A;  2VEW A;  3D1H A;  4JMK A;  3QCH A;  4QUM A;  1R6H A;  3O5X A;  3I80 A;  5K25 A;  1XXP A;  2F46 A;  4R0S A;  2I6I A;  3D9C A;  4RDD A;  1PTT A;  2GWO A;  4GE6 A;  1BZC A;  2B3O A;  1G1F A;  3RGO A;  2Q47 A;  4RI4 A;  4R0T A;  1A5Y A;  4RKK A;  1YZ4 A;  5GTJ A;  5KAD A;  3D44 A;  5BUG A;  2I4G A;  1FQ1 A;  2F6T A;  2QBR A;  2YDU A;  3I36 A;  4OHI A;  4GRZ A;  1C87 A;  1V3A A;  3BLU A;  3RZ2 A;  1ZCL A;  2WGP A;  5IBM A;  2QCJ A;  3S3F A;  2ESB A;  2CM8 A;  2A8B A;  1Q6M A;  1X24 A;  2CM3 A;  1Q6J A;  5EHR A;  1D5R A;  1OES A;  3D1O A;  3GXG A;  5IBS A;  3U96 A;  4WU2 A;  3S4O A;  2DXP A;  2PA5 A;  1PH0 A;  4ICZ A;  1BZH A;  4GE2 A;  2AZR A;  2CNE A;  2HCM A;  3V0E A;  1NWE A;  3A5K A;  2HNP A;  3F81 A;  2G59 A;  5K23 A;  3AWF A;  2NTA A;  4YR8 B;  2VEV A;  3V0J A;  1XXV A;  1G7F A;  1ZC0 A;  5EHP A;  1T49 A;  3NME A;  4GRY A;  2NV5 A;  3QCL A;  2J16 B;  5KA3 A;  2OUD A;  4QAP A;  1J4X A;  3EB1 A;  2I1Y A;  2CNF A;  5J8R A;  3B7O A;  4IKC A;  1T4J A;  2G6Z A;  2I3U A;  2FH7 A;  1NO6 A;  3V0F A;  2J16 A;  1BZJ A;  2HNQ A;  2NLK A;  2Y2F A;  4BJO A;  2HB1 A;  2B4P A;  3QCD A;  2QDP A;  4WOH A;  3S3K A;  1I9T A;  2GJT A;  2F6W A;  1NZ7 A;  1GWZ A;  2FJM A;  3O4S A;  2GP0 A;  3AWE A;  2F6Z A;  4KYQ A;  3OMH A;  3EU0 A;  2B07 A;  2I4E A;  4ERC A;  2CNH A;  4D3R A;  2HXP A;  2CMA A;  3ZM2 A;  1U26 A;  2I42 A;  2C46 A;  3QCK A;  1KAV A;  4JMJ A;  1P15 A;  4BPC A;  3O4T A;  2PI7 A;  5KA2 A;  5K22 A;  4GFU A;  4PYH A;  5BX1 A;  1PTU A;  1YPT A;  1Q1M A;  2CMC A;  4ZN5 A;  1PTV A;  2B49 A;  5LXQ B;  3EAX A;  2ZN7 A;  3PS5 A;  1WCH A;  2P4D A;  3V0H A;  1JLN A;  3H2X A;  3A5J A;  5HDE A;  2VEY A;  3SME A;  3OLR A;  1XM2 A;  5KA7 A;  3O4U A;  1QXK A;  3ZM1 A;  2I3R A;  3EZZ A;  2FJN A;  4I8N A;  4OHD A;  3RGQ A;  5M43 A;  2H4G A;  3N0A A;  2I5X A;  3D1Q A;  4GE5 A;  1GFY A;  2SHP A;  2BGD A;  2NT2 A;  1EEO A;  4AZ1 A;  2IMG A;  2H02 A;  3F41 A;  2E0T A;  3V0I A;  3V0G A;  2B4O A;  4WTY A;  4ZRT A;  2CMB A;  2I4H A;  2F70 A;  2H04 A;  4ZI4 A;  3MMJ A;  4Y2E A;  1NWL A;  3AWG A;  1YTW A;  1ZCK A;  2P6X A;  2BZL A;  3QCM A;  3D42 A;  1WAX A;  4Z6B A;  1ONZ A;  2A3K A;  2QBQ A;  2ZMM A;  3QCC A;  1L8K A;  4QBW A;  2QDM A;  4D3P A;  1G7G A;  2F6V A;  1G1G A;  2CNG A;  2NT7 A;  4QBE A;  5KAA A;  1YWF A;  2BGE A;  2C7S A;  2H4K A;  3SR9 A;  4OHH A;  2Q05 A;  5KA4 A;  4KI9 A;  4JNB A;  1VHR A;  2OC3 A;  2MBC A;  5BZX A;  5K9W A;  1C83 A;  3EMU A;  1FPZ A;  3I7Z A;  4OHE A;  1G1H A;  4YAA A;  2I6M A;  2NZ6 A;  3O3L A;  1QZ0 A;  3ZV2 A;  2VEX A;  4DGP A;  1U25 A;  1Q6T A;  2F6Y A;  2PBN A;  2QCT A;  1ZZW A;  4RH9 A;  4NWF A;  1ONY A;  2I75 A;  4NND A;  4PVG A;  3GXH A;  5KAC A;  1KAK A;  1NL9 A;  3CM3 A;  5AWX A;  2B4U A;  3QKQ A;  1YGU A;  4J51 A;  2PQ5 A;  5K9V A;  4S0G A;  3QCE A;  1OEU A;  3BLT A;  2QBS A;  2JJD A;  3MOW A;  3QCF A;  2H03 A;  1YTN A;  3M4U A;  2BIJ A;  4B04 A;  2BV5 A;  4R30 A;  3V0D A;  2CNI A;  1M3G A;  4NX8 A;  1OEM X;  3F99 A;  3S3H A;  5KA0 A;  5KA8 A;  4DGX A;  1I57 A;  4JBC A;  3MOZ A;  1RXD A;  3QCI A;  3QCB A;  3ZMP A;  2CM2 A;  2I6O A;  1SUG A;  3QCJ A;  1ECV A;  3S3E A;  1C86 A;  1EEN A;  3RO1 A;  2B4S A;  2QBP A; 
#chains in the Genus database with same CATH topology
 1YGR A;  1NNY A;  1C88 A;  1G4W R;  4HRF A;  3CWE A;  2OOQ A;  4GS0 A;  1U24 A;  3ZM3 A;  4OHL A;  4QUN A;  4RH5 A;  2F6F A;  4QAH A;  4Y14 A;  1MKP A;  4H1O A;  4C13 A;  3QKP A;  1XBO A;  5BZZ A;  1PA9 A;  4H34 A;  1C85 A;  1G4U S;  5KA9 A;  1I9S A;  2R0B A;  2Y67 A;  1L8G A;  4QDI A;  3ZMQ A;  5I6V A;  1OET A;  1OEV A;  2PSZ A;  1OHC A;  1LAR A;  4HJP A;  3UAG A;  2I6P A;  2OZ5 A;  5A5E A;  4GWF A;  3S4E A;  1YN9 A;  2Y68 A;  2JFF A;  1FPR A;  5K24 A;  1JF7 A;  2F71 A;  4NYH A;  1C84 A;  2VOR A;  4HJQ A;  1LQF A;  4KYR A;  4RHG A;  4QF5 A;  4GFV A;  1OEO X;  1E8C A;  2QDC A;  2I6J A;  2J17 A;  2HY3 A;  1PYN A;  2JFH A;  4HV4 A;  1PXH A;  3F9B A;  1WRM A;  2HC2 A;  1PTY A;  2AHS A;  2HVL A;  1Q6S A;  3ZM0 A;  4WU3 A;  3BRH A;  2RF6 A;  2HC1 A;  2H4V A;  3QCG A;  1XRI A;  5KAB A;  1Q6N A;  1LYV A;  4TVV A;  2VEU A;  2XJA A;  1AAX A;  1RPM A;  1T48 A;  1YTS A;  2CM7 A;  2CJZ A;  1OHD A;  5MMZ B;  2CFV A;  1OHE A;  2M3V A;  2QEP A;  4MBB A;  4D3Q A;  2PT0 A;  2XPC A;  1YFO A;  4RI5 A;  3LJ8 A;  3BM8 A;  3F9A A;  3LK7 A;  1Q6P A;  2Y96 A;  3QCN A;  2WJP A;  4NWG A;  5KA1 A;  1PA1 A;  2VEW A;  3D1H A;  4JMK A;  3QCH A;  4QUM A;  1R6H A;  3O5X A;  3I80 A;  5K25 A;  1XXP A;  2F46 A;  2Y66 A;  4R0S A;  2I6I A;  3D9C A;  4RDD A;  1PTT A;  2GWO A;  4GE6 A;  1BZC A;  2B3O A;  1G1F A;  3RGO A;  3N2A A;  2Q47 A;  4RI4 A;  4R0T A;  1A5Y A;  4RKK A;  1YZ4 A;  4ZIY A;  5GTJ A;  5KAD A;  3D44 A;  5BUG A;  2I4G A;  1FQ1 A;  2F6T A;  2QBR A;  2UUO A;  3ZM6 A;  2YDU A;  3I36 A;  4OHI A;  4GRZ A;  1C87 A;  1V3A A;  3BLU A;  2GC5 A;  3RZ2 A;  1ZCL A;  2WGP A;  5IBM A;  2QCJ A;  3S3F A;  2ESB A;  2CM8 A;  2A8B A;  3ZL8 A;  1Q6M A;  1X24 A;  2CM3 A;  1Q6J A;  1JBW A;  5EHR A;  1D5R A;  1OES A;  3D1O A;  3GXG A;  5IBS A;  2UAG A;  3U96 A;  4WU2 A;  3S4O A;  2DXP A;  2PA5 A;  1PH0 A;  4ICZ A;  1BZH A;  4GE2 A;  2AZR A;  2CNE A;  2HCM A;  3V0E A;  1EEH A;  1NWE A;  3A5K A;  2HNP A;  3F81 A;  2G59 A;  1W7K A;  1J6U A;  5K23 A;  3AWF A;  2NTA A;  4YR8 B;  2VEV A;  3V0J A;  1XXV A;  4C12 A;  1G7F A;  1ZC0 A;  4CVL A;  5EHP A;  1GQY A;  1T49 A;  1E0D A;  3NME A;  4GRY A;  2NV5 A;  3QCL A;  2J16 B;  5KA3 A;  2OUD A;  4QAP A;  1J4X A;  3EB1 A;  2I1Y A;  2CNF A;  5J8R A;  3B7O A;  4IKC A;  1T4J A;  2G6Z A;  2I3U A;  2FH7 A;  1NO6 A;  3V0F A;  2J16 A;  2AM1 A;  1BZJ A;  2HNQ A;  2NLK A;  2Y2F A;  4BJO A;  2HB1 A;  2B4P A;  3QCD A;  2QDP A;  3QCZ A;  4WOH A;  3S3K A;  1I9T A;  1FGS A;  2GJT A;  2F6W A;  1NZ7 A;  1GWZ A;  2FJM A;  3O4S A;  2GP0 A;  3AWE A;  3HN7 A;  2F6Z A;  4KYQ A;  3OMH A;  3EU0 A;  2B07 A;  2I4E A;  4ERC A;  2CNH A;  4D3R A;  1W78 A;  2HXP A;  2CMA A;  3ZM2 A;  1U26 A;  2I42 A;  2C46 A;  3QCK A;  1KAV A;  4JMJ A;  1P15 A;  4BPC A;  3O4T A;  4UAG A;  2PI7 A;  5KA2 A;  5K22 A;  4GFU A;  4PYH A;  5BX1 A;  1PTU A;  1YPT A;  3NRS A;  1Q1M A;  2F00 A;  2CMC A;  5A5F A;  4ZN5 A;  1PTV A;  2B49 A;  1GQQ A;  5LXQ B;  3EAX A;  2JFG A;  2ZN7 A;  3PS5 A;  1WCH A;  2AM2 A;  4CVM A;  2P4D A;  3V0H A;  2VTD A;  1JLN A;  3H2X A;  3A5J A;  5HDE A;  2VEY A;  3SME A;  3OLR A;  1XM2 A;  5KA7 A;  3O4U A;  1QXK A;  3ZM1 A;  4BUC A;  2I3R A;  3EZZ A;  2FJN A;  4I8N A;  3MVN A;  4OHD A;  3RGQ A;  5M43 A;  2H4G A;  2VOS A;  3N0A A;  2I5X A;  3D1Q A;  4GE5 A;  1GFY A;  2SHP A;  2BGD A;  2NT2 A;  1EEO A;  4AZ1 A;  2GC6 A;  2IMG A;  2H02 A;  3F41 A;  2E0T A;  3V0I A;  3V0G A;  2B4O A;  4WTY A;  4ZRT A;  4BUB A;  2CMB A;  2I4H A;  2F70 A;  2H04 A;  4ZI4 A;  3MMJ A;  4Y2E A;  1NWL A;  3AWG A;  1YTW A;  1ZCK A;  2P6X A;  2BZL A;  3QCM A;  3D42 A;  1WAX A;  2Y1O A;  4CVK A;  4Z6B A;  1ONZ A;  2A3K A;  2QBQ A;  2ZMM A;  2WTZ A;  3QCC A;  1L8K A;  4QBW A;  2QDM A;  4D3P A;  1G7G A;  1O5Z A;  2F6V A;  1G1G A;  2CNG A;  2NT7 A;  4QBE A;  5KAA A;  1YWF A;  2BGE A;  2C7S A;  2H4K A;  2VTE A;  3SR9 A;  1GG4 A;  2X5O A;  4OHH A;  3PYZ A;  2Q05 A;  5KA4 A;  2GCA A;  4KI9 A;  4JNB A;  1VHR A;  2OC3 A;  2MBC A;  5BZX A;  5K9W A;  1C83 A;  3EMU A;  1FPZ A;  3I7Z A;  1JBV A;  4OHE A;  1G1H A;  4YAA A;  2I6M A;  2NZ6 A;  3O3L A;  1QZ0 A;  3ZV2 A;  2VEX A;  4DGP A;  1U25 A;  1Q6T A;  2F6Y A;  2PBN A;  2QCT A;  1ZZW A;  4RH9 A;  4NWF A;  1ONY A;  2I75 A;  1P3D A;  4NND A;  4PVG A;  3GXH A;  5KAC A;  1KAK A;  1NL9 A;  3CM3 A;  5AWX A;  2B4U A;  3QKQ A;  1YGU A;  4J51 A;  2PQ5 A;  1P31 A;  5K9V A;  4S0G A;  3QCE A;  1OEU A;  3BLT A;  2QBS A;  3ZM5 A;  2GCB A;  2JJD A;  3MOW A;  3QCF A;  2H03 A;  1YTN A;  3M4U A;  2BIJ A;  4B04 A;  2BV5 A;  4R30 A;  3V0D A;  2CNI A;  1M3G A;  4NX8 A;  1OEM X;  3F99 A;  3S3H A;  5KA0 A;  5KA8 A;  4DGX A;  1I57 A;  4JBC A;  3MOZ A;  1RXD A;  1UAG A;  2UUP A;  3QCI A;  3QCB A;  3ZMP A;  2CM2 A;  2I6O A;  1SUG A;  3QCJ A;  1ECV A;  3S3E A;  1C86 A;  1EEN A;  3RO1 A;  2B4S A;  2QBP A; 
#chains in the Genus database with same CATH homology
 1YGR A;  1NNY A;  1C88 A;  1G4W R;  4HRF A;  3CWE A;  2OOQ A;  4GS0 A;  1U24 A;  3ZM3 A;  4OHL A;  4QUN A;  4RH5 A;  2F6F A;  4QAH A;  4Y14 A;  1MKP A;  4H1O A;  3QKP A;  1XBO A;  5BZZ A;  1PA9 A;  4H34 A;  1C85 A;  1G4U S;  5KA9 A;  1I9S A;  2R0B A;  1L8G A;  3ZMQ A;  5I6V A;  1OET A;  1OEV A;  2PSZ A;  1OHC A;  1LAR A;  4HJP A;  2I6P A;  2OZ5 A;  4GWF A;  3S4E A;  1YN9 A;  1FPR A;  5K24 A;  1JF7 A;  2F71 A;  4NYH A;  1C84 A;  4HJQ A;  1LQF A;  4KYR A;  4RHG A;  4GFV A;  1OEO X;  2QDC A;  2I6J A;  2J17 A;  2HY3 A;  1PYN A;  3F9B A;  1PXH A;  1WRM A;  2HC2 A;  1PTY A;  2AHS A;  2HVL A;  1Q6S A;  3ZM0 A;  4WU3 A;  3BRH A;  2RF6 A;  2HC1 A;  2H4V A;  3QCG A;  1XRI A;  5KAB A;  1Q6N A;  1LYV A;  4TVV A;  2VEU A;  1AAX A;  1RPM A;  1T48 A;  1YTS A;  2CM7 A;  2CJZ A;  1OHD A;  5MMZ B;  2CFV A;  1OHE A;  2M3V A;  2QEP A;  4MBB A;  4D3Q A;  2PT0 A;  1YFO A;  4RI5 A;  3LJ8 A;  3BM8 A;  3F9A A;  1Q6P A;  2Y96 A;  3QCN A;  4NWG A;  5KA1 A;  1PA1 A;  2VEW A;  3D1H A;  4JMK A;  3QCH A;  4QUM A;  1R6H A;  3O5X A;  3I80 A;  5K25 A;  1XXP A;  2F46 A;  4R0S A;  2I6I A;  3D9C A;  4RDD A;  1PTT A;  2GWO A;  4GE6 A;  1BZC A;  2B3O A;  1G1F A;  3RGO A;  2Q47 A;  4RI4 A;  4R0T A;  1A5Y A;  4RKK A;  1YZ4 A;  5GTJ A;  5KAD A;  3D44 A;  5BUG A;  2I4G A;  1FQ1 A;  2F6T A;  2QBR A;  2YDU A;  3I36 A;  4OHI A;  4GRZ A;  1C87 A;  1V3A A;  3BLU A;  3RZ2 A;  1ZCL A;  2WGP A;  5IBM A;  2QCJ A;  3S3F A;  2ESB A;  2CM8 A;  2A8B A;  1Q6M A;  1X24 A;  2CM3 A;  1Q6J A;  5EHR A;  1D5R A;  1OES A;  3D1O A;  3GXG A;  5IBS A;  3U96 A;  4WU2 A;  3S4O A;  2DXP A;  2PA5 A;  1PH0 A;  4ICZ A;  1BZH A;  4GE2 A;  2AZR A;  2CNE A;  2HCM A;  3V0E A;  1NWE A;  3A5K A;  2HNP A;  3F81 A;  2G59 A;  5K23 A;  3AWF A;  2NTA A;  4YR8 B;  2VEV A;  3V0J A;  1XXV A;  1G7F A;  1ZC0 A;  5EHP A;  1T49 A;  3NME A;  4GRY A;  2NV5 A;  3QCL A;  2J16 B;  5KA3 A;  2OUD A;  4QAP A;  1J4X A;  3EB1 A;  2I1Y A;  2CNF A;  5J8R A;  3B7O A;  4IKC A;  1T4J A;  2G6Z A;  2I3U A;  2FH7 A;  1NO6 A;  3V0F A;  2J16 A;  1BZJ A;  2HNQ A;  2NLK A;  2Y2F A;  4BJO A;  2HB1 A;  2B4P A;  3QCD A;  2QDP A;  4WOH A;  3S3K A;  1I9T A;  2GJT A;  2F6W A;  1NZ7 A;  1GWZ A;  2FJM A;  3O4S A;  2GP0 A;  3AWE A;  2F6Z A;  4KYQ A;  3OMH A;  3EU0 A;  2B07 A;  2I4E A;  4ERC A;  2CNH A;  4D3R A;  2HXP A;  2CMA A;  3ZM2 A;  1U26 A;  2I42 A;  2C46 A;  3QCK A;  1KAV A;  4JMJ A;  1P15 A;  4BPC A;  3O4T A;  2PI7 A;  5KA2 A;  5K22 A;  4GFU A;  4PYH A;  5BX1 A;  1PTU A;  1YPT A;  1Q1M A;  2CMC A;  4ZN5 A;  1PTV A;  2B49 A;  5LXQ B;  3EAX A;  2ZN7 A;  3PS5 A;  1WCH A;  2P4D A;  3V0H A;  1JLN A;  3H2X A;  3A5J A;  5HDE A;  2VEY A;  3SME A;  3OLR A;  1XM2 A;  5KA7 A;  3O4U A;  1QXK A;  3ZM1 A;  2I3R A;  3EZZ A;  2FJN A;  4I8N A;  4OHD A;  3RGQ A;  5M43 A;  2H4G A;  3N0A A;  2I5X A;  3D1Q A;  4GE5 A;  1GFY A;  2SHP A;  2BGD A;  2NT2 A;  1EEO A;  4AZ1 A;  2IMG A;  2H02 A;  3F41 A;  2E0T A;  3V0I A;  3V0G A;  2B4O A;  4WTY A;  4ZRT A;  2CMB A;  2I4H A;  2F70 A;  2H04 A;  4ZI4 A;  3MMJ A;  4Y2E A;  1NWL A;  3AWG A;  1YTW A;  1ZCK A;  2P6X A;  2BZL A;  3QCM A;  3D42 A;  1WAX A;  4Z6B A;  1ONZ A;  2A3K A;  2QBQ A;  2ZMM A;  3QCC A;  1L8K A;  4QBW A;  2QDM A;  4D3P A;  1G7G A;  2F6V A;  1G1G A;  2CNG A;  2NT7 A;  4QBE A;  5KAA A;  1YWF A;  2BGE A;  2C7S A;  2H4K A;  3SR9 A;  4OHH A;  2Q05 A;  5KA4 A;  4KI9 A;  4JNB A;  1VHR A;  2OC3 A;  2MBC A;  5BZX A;  5K9W A;  1C83 A;  3EMU A;  1FPZ A;  3I7Z A;  4OHE A;  1G1H A;  4YAA A;  2I6M A;  2NZ6 A;  3O3L A;  1QZ0 A;  3ZV2 A;  2VEX A;  4DGP A;  1U25 A;  1Q6T A;  2F6Y A;  2PBN A;  2QCT A;  1ZZW A;  4RH9 A;  4NWF A;  1ONY A;  2I75 A;  4NND A;  4PVG A;  3GXH A;  5KAC A;  1KAK A;  1NL9 A;  3CM3 A;  5AWX A;  2B4U A;  3QKQ A;  1YGU A;  4J51 A;  2PQ5 A;  5K9V A;  4S0G A;  3QCE A;  1OEU A;  3BLT A;  2QBS A;  2JJD A;  3MOW A;  3QCF A;  2H03 A;  1YTN A;  3M4U A;  2BIJ A;  4B04 A;  2BV5 A;  4R30 A;  3V0D A;  2CNI A;  1M3G A;  4NX8 A;  1OEM X;  3F99 A;  3S3H A;  5KA0 A;  5KA8 A;  4DGX A;  1I57 A;  4JBC A;  3MOZ A;  1RXD A;  3QCI A;  3QCB A;  3ZMP A;  2CM2 A;  2I6O A;  1SUG A;  3QCJ A;  1ECV A;  3S3E A;  1C86 A;  1EEN A;  3RO1 A;  2B4S A;  2QBP A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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