1GFYA

Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatase 1b and alpha
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
296
structure length
296
Chain Sequence
MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYVNVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKTYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRCQLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B)
publication title Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alpha.
pubmed doi rcsb
source organism Homo sapiens
total genus 111
structure length 296
sequence length 296
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1gfyA00
1ZZWA 2CMCA 2CMAA 1R6HA 1YTNA 2Y96A 2Q05A 2HVLA 4RDDA 4NNDA 2RF6A 1Q6NA 3BM8A 4H1OA 3I80A 2QEPA 5HDEA 1BZHA 2J17A 3O4UA 4GE2A 1XRIA 1ECVA 3ZM3A 2NV5A 4R0SA 1YGRA 2CM8A 2H4VA 3EZZA 2G6ZA 4MBBA 3D1HA 4NWFA 1P15A 1XM2A 2NZ6A 5BUGA 4RI4A 3V0HA 1PA1A 1EENA 1G7FA 2I42A 1OEUA 3O5XA 5KACA 4HRFA 4Y14A 3ZM2A 2OOQA 2E0TA 3O3LA 1PXHA 1T4JA 3F9AA 4QUMA 2FJMA 2BGDA 2QBRA 1C84A 1PTYA 3D42A 4OHHA 2B4UA 2DXPA 4OHDA 5K24A 2I6MA 3EAXA 4D3QA 1NNYA 5K22A 2PQ5A 3ZMPA 2G59A 3OLRA 3MOWA 2H4KA 4S0GA 3V0DA 2ZN7A 4GE5A 3S3FA 2P4DA 4QAPA 1Q6JA 3MMJA 4JBCA 4GS0A 1NWEA 3U96A 2C7SA 2OC3A 2B4SA 1GFYA 2CM3A 3BRHA 1OHDA 2I6IA 1G1GA 2I75A 4QBWA 2AHSA 1JF7A 1EEOA 2I3RA 2P6XA 3M4UA 1WCHA 3S4EA 1I9TA 4IKCA 2H4GA 2CMBA 2I6JA 2B4PA 2QBQA 2I6PA 2HXPA 2CJZA 4TVVA 2F70A 2NLKA 1NL9A 2J16A 2B07A 1LYVA 1MKPA 1YTWA 2NT2A 3QCDA 4H34A 1D5RA 5KA2A 4OHLA 2B49A 2A3KA 4WOHA 3QKPA 2IMGA 5IBMA 1NO6A 1GWZA 2ESBA 4GWFA 1Q6MA 3EU0A 3EB1A 2I4EA 4R30A 4RI5A 1PTVA 1PTUA 2H04A 3ZM0A 3S3HA 3BLUA 3D1QA 2GP0A 3QKQA 2J16B 4HJQA 1NWLA 3H2XA 3QCNA 4NYHA 2B4OA 1YWFA 1G7GA 1I9SA 1C87A 1YGUA 1PA9A 2R0BA 3RZ2A 2MBCA 3GXHA 1RXDA 2F46A 2PI7A 3S4OA 1PH0A 1YZ4A 4ZRTA 1XXVA 2H03A 2ZMMA 2JJDA 3D9CA 2CM2A 1Q1MA 2PSZA 2FJNA 2QCJA 2QDPA 3O4TA 3PS5A 1OHCA 1FPRA 1U26A 2NT7A 3QCGA 3QCKA 4JMKA 2QDMA 3D1OA 3F41A 1AAXA 5M43A 5EHPA 1VHRA 2QCTA 5KABA 3QCFA 3V0JA 1L8GA 3LJ8A 2QBSA 3ZV2A 1WAXA 1G1FA 2HB1A 4GE6A 2OZ5A 1L8KA 4RKKA 2HNQA 3MOZA 3S3EA 2WGPA 1C86A 2CNHA 2I4HA 4ICZA 4J51A 5LXQB 2F6TA 3OMHA 1C88A 2F6ZA 5AWXA 2F6WA 4PYHA 5KA9A 1Q6PA 2SHPA 1X24A 2VEUA 4R0TA 1FPZA 4OHEA 3QCLA 4RHGA 4BJOA 5K25A 1ZCLA 3QCEA 2CFVA 2GJTA 2HNPA 2CNIA 3N0AA 4WU3A 1XBOA 2AZRA 1G4US 4DGXA 5KA3A 5KAAA 1I57A 3F81A 4QUNA 3CM3A 5KA1A 5I6VA 2VEYA 3I36A 4I8NA 4D3RA 4D3PA 1LQFA 1M3GA 4JNBA 3F9BA 3V0FA 2F6VA 5KA7A 3AWGA 1A5YA 1Q6SA 1YN9A 3CWEA 1U25A 2F6FA 1PTTA 1ONYA 4AZ1A 1KAKA 5K9WA 4JMJA 4ERCA 4KI9A 2QBPA 4BPCA 1SUGA 4ZI4A 3QCCA 1JLNA 3I7ZA 2I1YA 3V0EA 5K23A 1RPMA 1C83A 5IBSA 2B3OA 1C85A 3A5KA 2I6OA 2FH7A 3NMEA 2F6YA 2HC1A 2I4GA 2BIJA 4WU2A 3RO1A 4GRYA 1XXPA 2Y2FA 5MMZB 4QBEA 1OHEA 4NWGA 4GFUA 3S3KA 1T48A 3EMUA 3A5JA 1OESA 3SMEA 5KADA 1YFOA 2HCMA 5KA8A 2A8BA 2H02A 5BZZA 2PT0A 2VEVA 1YTSA 1WRMA 3ZM1A 5KA4A 3QCMA 1NZ7A 4GRZA 3QCJA 1ZC0A 4GFVA 4DGPA 2C46A 3BLTA 1LARA 2NTAA 1BZJA 1OEVA 5GTJA 2HY3A 2VEXA 1T49A 2BV5A 2CM7A 2QDCA 3AWFA 1ZCKA 3O4SA 1OETA 2I3UA 1G4WR 4B04A 1OEOX 4WTYA 3V0GA 3AWEA 2Q47A 3QCIA 4RH5A 1QZ0A 3QCBA 4HJPA 2CNFA 5K9VA 2BGEA 2I5XA 2PBNA 1PYNA 1Q6TA 2M3VA 2BZLA 2OUDA 4OHIA 2F71A 5EHRA 4KYQA 3D44A 1J4XA 1U24A 2VEWA 1OEMX 3QCHA 3ZMQA 3B7OA 4Y2EA 2GWOA 4QAHA 1V3AA 4YR8B 1FQ1A 3SR9A 1ONZA 2CNGA 4YAAA 5BX1A 4NX8A 2HC2A 4KYRA 5J8RA 5KA0A 3GXGA 1G1HA 2CNEA 1QXKA 3F99A 3RGOA 4RH9A 1KAVA 3RGQA 4ZN5A 2PA5A 2YDUA 1YPTA 1BZCA 5BZXA 3V0IA 4Z6BA 4PVGA
chains in the Genus database with same CATH superfamily
1ZZWA 2CMCA 2CMAA 1R6HA 1YTNA 2Y96A 2Q05A 2HVLA 4RDDA 4NNDA 2RF6A 1Q6NA 4UAGA 3BM8A 4H1OA 3I80A 2QEPA 5HDEA 1BZHA 2J17A 3O4UA 4GE2A 1XRIA 1ECVA 3ZM3A 2NV5A 4R0SA 1YGRA 2CM8A 2H4VA 3EZZA 2G6ZA 4MBBA 2UAGA 3D1HA 4NWFA 1P15A 1XM2A 1E0DA 2NZ6A 5BUGA 4RI4A 2XPCA 3V0HA 1PA1A 1EENA 1G7FA 2I42A 1OEUA 3O5XA 5KACA 4HRFA 4Y14A 3ZM2A 2OOQA 2E0TA 3O3LA 1PXHA 2X5OA 1T4JA 2WTZA 3F9AA 4QUMA 2FJMA 2BGDA 2QBRA 1C84A 1PTYA 2JFHA 3D42A 3MVNA 2B4UA 4OHHA 2DXPA 4OHDA 5K24A 2I6MA 3EAXA 3N2AA 4D3QA 1NNYA 5K22A 2PQ5A 3ZMPA 2G59A 3OLRA 3MOWA 2H4KA 4S0GA 3V0DA 2ZN7A 4GE5A 3S3FA 2P4DA 4QAPA 1Q6JA 3PYZA 3MMJA 2XJAA 4JBCA 4GS0A 1NWEA 3U96A 2C7SA 2OC3A 2B4SA 1GFYA 2CM3A 3BRHA 1OHDA 2GC6A 2I6IA 1G1GA 2I75A 4QBWA 2AHSA 1JF7A 2AM1A 1EEOA 2I3RA 2P6XA 2WJPA 2Y67A 3M4UA 1WCHA 3S4EA 1I9TA 4IKCA 2H4GA 2CMBA 2I6JA 2B4PA 2QBQA 3ZM6A 3ZM5A 2I6PA 2HXPA 4BUBA 2CJZA 4TVVA 2F70A 2NLKA 1NL9A 2J16A 4HV4A 2B07A 1LYVA 1MKPA 1YTWA 2NT2A 3QCDA 4H34A 1D5RA 2Y66A 2Y1OA 5KA2A 1UAGA 1W7KA 4OHLA 2B49A 1JBVA 2A3KA 3NRSA 4WOHA 3QKPA 2IMGA 5IBMA 4CVMA 1NO6A 1GWZA 2ESBA 4GWFA 1Q6MA 3EU0A 3EB1A 2I4EA 4R30A 4RI5A 1PTVA 1PTUA 2H04A 3ZM0A 3S3HA 3BLUA 3D1QA 2GP0A 3QKQA 2J16B 4HJQA 1NWLA 3H2XA 3QCNA 2VORA 4NYHA 2B4OA 1YWFA 1G7GA 1I9SA 1C87A 1YGUA 1PA9A 2R0BA 3RZ2A 2MBCA 3GXHA 1RXDA 2F46A 2PI7A 3S4OA 1PH0A 1YZ4A 4ZRTA 1XXVA 1GG4A 2H03A 2ZMMA 2JJDA 3D9CA 2CM2A 1Q1MA 2PSZA 2FJNA 2QCJA 2QDPA 3O4TA 3PS5A 1OHCA 1FPRA 1U26A 2NT7A 3QCGA 3QCKA 4JMKA 2QDMA 3D1OA 4CVLA 3F41A 1AAXA 5M43A 5EHPA 1VHRA 2QCTA 5KABA 3QCFA 3V0JA 1L8GA 3LJ8A 2QBSA 3ZV2A 1WAXA 1G1FA 2HB1A 4GE6A 2OZ5A 1L8KA 4RKKA 2HNQA 1J6UA 3MOZA 4C12A 3S3EA 2WGPA 1C86A 2CNHA 2I4HA 4ICZA 2JFGA 4J51A 5LXQB 2F6TA 3OMHA 1C88A 2F6ZA 5AWXA 2F6WA 4PYHA 5KA9A 1Q6PA 2SHPA 1X24A 2GC5A 2VEUA 3QCZA 4R0TA 1FPZA 4OHEA 2Y68A 3QCLA 4RHGA 4BJOA 5K25A 1ZCLA 3QCEA 4QF5A 2CFVA 2GJTA 2HNPA 2CNIA 3N0AA 5A5FA 4WU3A 1XBOA 2AZRA 1G4US 4DGXA 5KA3A 5KAAA 2GCAA 1I57A 3F81A 4QUNA 3CM3A 5KA1A 5I6VA 2VEYA 3I36A 4I8NA 4D3RA 4D3PA 1LQFA 1M3GA 4JNBA 3F9BA 3V0FA 2F6VA 5KA7A 3AWGA 1A5YA 1Q6SA 1YN9A 3CWEA 1U25A 2F6FA 1PTTA 1ONYA 4C13A 3UAGA 4AZ1A 1KAKA 5K9WA 4JMJA 4ERCA 4KI9A 2QBPA 4BPCA 1SUGA 4ZI4A 3QCCA 1JLNA 3I7ZA 2I1YA 3V0EA 5K23A 1RPMA 1C83A 5IBSA 2B3OA 1C85A 3A5KA 2I6OA 2FH7A 3NMEA 2F6YA 2HC1A 2I4GA 2BIJA 3HN7A 2UUOA 4WU2A 3RO1A 4GRYA 1XXPA 2Y2FA 5MMZB 4QBEA 1OHEA 4NWGA 4GFUA 3S3KA 1E8CA 1T48A 3EMUA 3A5JA 4ZIYA 1OESA 3SMEA 3ZL8A 5KADA 1YFOA 2HCMA 5KA8A 2A8BA 2H02A 5BZZA 2PT0A 2VEVA 1YTSA 1WRMA 3ZM1A 5KA4A 3QCMA 1NZ7A 4GRZA 3LK7A 1EEHA 3QCJA 1ZC0A 4GFVA 4DGPA 2C46A 3BLTA 1LARA 2NTAA 1BZJA 1OEVA 5GTJA 2HY3A 4CVKA 2VEXA 1GQYA 1T49A 2BV5A 2CM7A 2QDCA 3AWFA 1ZCKA 3O4SA 1O5ZA 1OETA 2I3UA 1G4WR 4B04A 4BUCA 1OEOX 4WTYA 3V0GA 3AWEA 2Q47A 3QCIA 4RH5A 1QZ0A 3QCBA 4HJPA 2CNFA 5K9VA 2BGEA 2I5XA 5A5EA 2PBNA 1PYNA 1Q6TA 2F00A 2M3VA 2BZLA 2OUDA 4OHIA 2F71A 4QDIA 5EHRA 4KYQA 3D44A 1J4XA 1U24A 2VEWA 2AM2A 1OEMX 3QCHA 3ZMQA 3B7OA 4Y2EA 2GWOA 4QAHA 2VOSA 2VTEA 1V3AA 4YR8B 1FQ1A 3SR9A 1FGSA 1ONZA 1P3DA 2CNGA 4YAAA 2GCBA 5BX1A 4NX8A 2HC2A 4KYRA 5J8RA 5KA0A 1P31A 3GXGA 1G1HA 2CNEA 1QXKA 3F99A 3RGOA 4RH9A 1KAVA 3RGQA 4ZN5A 2PA5A 1JBWA 2YDUA 1GQQA 2VTDA 1YPTA 1BZCA 2JFFA 5BZXA 3V0IA 4Z6BA 1W78A 2UUPA 4PVGA
chains in the Genus database with same CATH topology
1ZZWA 2CMCA 2CMAA 1R6HA 1YTNA 2Y96A 2Q05A 2HVLA 4RDDA 4NNDA 2RF6A 1Q6NA 3BM8A 4H1OA 3I80A 2QEPA 5HDEA 1BZHA 2J17A 3O4UA 4GE2A 1XRIA 1ECVA 3ZM3A 2NV5A 4R0SA 1YGRA 2CM8A 2H4VA 3EZZA 2G6ZA 4MBBA 3D1HA 4NWFA 1P15A 1XM2A 2NZ6A 5BUGA 4RI4A 3V0HA 1PA1A 1EENA 1G7FA 2I42A 1OEUA 3O5XA 5KACA 4HRFA 4Y14A 3ZM2A 2OOQA 2E0TA 3O3LA 1PXHA 1T4JA 3F9AA 4QUMA 2FJMA 2BGDA 2QBRA 1C84A 1PTYA 3D42A 4OHHA 2B4UA 2DXPA 4OHDA 5K24A 2I6MA 3EAXA 4D3QA 1NNYA 5K22A 2PQ5A 3ZMPA 2G59A 3OLRA 3MOWA 2H4KA 4S0GA 3V0DA 2ZN7A 4GE5A 3S3FA 2P4DA 4QAPA 1Q6JA 3MMJA 4JBCA 4GS0A 1NWEA 3U96A 2C7SA 2OC3A 2B4SA 1GFYA 2CM3A 3BRHA 1OHDA 2I6IA 1G1GA 2I75A 4QBWA 2AHSA 1JF7A 1EEOA 2I3RA 2P6XA 3M4UA 1WCHA 3S4EA 1I9TA 4IKCA 2H4GA 2CMBA 2I6JA 2B4PA 2QBQA 2I6PA 2HXPA 2CJZA 4TVVA 2F70A 2NLKA 1NL9A 2J16A 2B07A 1LYVA 1MKPA 1YTWA 2NT2A 3QCDA 4H34A 1D5RA 5KA2A 4OHLA 2B49A 2A3KA 4WOHA 3QKPA 2IMGA 5IBMA 1NO6A 1GWZA 2ESBA 4GWFA 1Q6MA 3EU0A 3EB1A 2I4EA 4R30A 4RI5A 1PTVA 1PTUA 2H04A 3ZM0A 3S3HA 3BLUA 3D1QA 2GP0A 3QKQA 2J16B 4HJQA 1NWLA 3H2XA 3QCNA 4NYHA 2B4OA 1YWFA 1G7GA 1I9SA 1C87A 1YGUA 1PA9A 2R0BA 3RZ2A 2MBCA 3GXHA 1RXDA 2F46A 2PI7A 3S4OA 1PH0A 1YZ4A 4ZRTA 1XXVA 2H03A 2ZMMA 2JJDA 3D9CA 2CM2A 1Q1MA 2PSZA 2FJNA 2QCJA 2QDPA 3O4TA 3PS5A 1OHCA 1FPRA 1U26A 2NT7A 3QCGA 3QCKA 4JMKA 2QDMA 3D1OA 3F41A 1AAXA 5M43A 5EHPA 1VHRA 2QCTA 5KABA 3QCFA 3V0JA 1L8GA 3LJ8A 2QBSA 3ZV2A 1WAXA 1G1FA 2HB1A 4GE6A 2OZ5A 1L8KA 4RKKA 2HNQA 3MOZA 3S3EA 2WGPA 1C86A 2CNHA 2I4HA 4ICZA 4J51A 5LXQB 2F6TA 3OMHA 1C88A 2F6ZA 5AWXA 2F6WA 4PYHA 5KA9A 1Q6PA 2SHPA 1X24A 2VEUA 4R0TA 1FPZA 4OHEA 3QCLA 4RHGA 4BJOA 5K25A 1ZCLA 3QCEA 2CFVA 2GJTA 2HNPA 2CNIA 3N0AA 4WU3A 1XBOA 2AZRA 1G4US 4DGXA 5KA3A 5KAAA 1I57A 3F81A 4QUNA 3CM3A 5KA1A 5I6VA 2VEYA 3I36A 4I8NA 4D3RA 4D3PA 1LQFA 1M3GA 4JNBA 3F9BA 3V0FA 2F6VA 5KA7A 3AWGA 1A5YA 1Q6SA 1YN9A 3CWEA 1U25A 2F6FA 1PTTA 1ONYA 4AZ1A 1KAKA 5K9WA 4JMJA 4ERCA 4KI9A 2QBPA 4BPCA 1SUGA 4ZI4A 3QCCA 1JLNA 3I7ZA 2I1YA 3V0EA 5K23A 1RPMA 1C83A 5IBSA 2B3OA 1C85A 3A5KA 2I6OA 2FH7A 3NMEA 2F6YA 2HC1A 2I4GA 2BIJA 4WU2A 3RO1A 4GRYA 1XXPA 2Y2FA 5MMZB 4QBEA 1OHEA 4NWGA 4GFUA 3S3KA 1T48A 3EMUA 3A5JA 1OESA 3SMEA 5KADA 1YFOA 2HCMA 5KA8A 2A8BA 2H02A 5BZZA 2PT0A 2VEVA 1YTSA 1WRMA 3ZM1A 5KA4A 3QCMA 1NZ7A 4GRZA 3QCJA 1ZC0A 4GFVA 4DGPA 2C46A 3BLTA 1LARA 2NTAA 1BZJA 1OEVA 5GTJA 2HY3A 2VEXA 1T49A 2BV5A 2CM7A 2QDCA 3AWFA 1ZCKA 3O4SA 1OETA 2I3UA 1G4WR 4B04A 1OEOX 4WTYA 3V0GA 3AWEA 2Q47A 3QCIA 4RH5A 1QZ0A 3QCBA 4HJPA 2CNFA 5K9VA 2BGEA 2I5XA 2PBNA 1PYNA 1Q6TA 2M3VA 2BZLA 2OUDA 4OHIA 2F71A 5EHRA 4KYQA 3D44A 1J4XA 1U24A 2VEWA 1OEMX 3QCHA 3ZMQA 3B7OA 4Y2EA 2GWOA 4QAHA 1V3AA 4YR8B 1FQ1A 3SR9A 1ONZA 2CNGA 4YAAA 5BX1A 4NX8A 2HC2A 4KYRA 5J8RA 5KA0A 3GXGA 1G1HA 2CNEA 1QXKA 3F99A 3RGOA 4RH9A 1KAVA 3RGQA 4ZN5A 2PA5A 2YDUA 1YPTA 1BZCA 5BZXA 3V0IA 4Z6BA 4PVGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZZW A;  2CMC A;  2CMA A;  1R6H A;  1YTN A;  2Y96 A;  2Q05 A;  2HVL A;  4RDD A;  4NND A;  2RF6 A;  1Q6N A;  3BM8 A;  4H1O A;  3I80 A;  2QEP A;  5HDE A;  1BZH A;  2J17 A;  3O4U A;  4GE2 A;  1XRI A;  1ECV A;  3ZM3 A;  2NV5 A;  4R0S A;  1YGR A;  2CM8 A;  2H4V A;  3EZZ A;  2G6Z A;  4MBB A;  3D1H A;  4NWF A;  1P15 A;  1XM2 A;  2NZ6 A;  5BUG A;  4RI4 A;  3V0H A;  1PA1 A;  1EEN A;  1G7F A;  2I42 A;  1OEU A;  3O5X A;  5KAC A;  4HRF A;  4Y14 A;  3ZM2 A;  2OOQ A;  2E0T A;  3O3L A;  1PXH A;  1T4J A;  3F9A A;  4QUM A;  2FJM A;  2BGD A;  2QBR A;  1C84 A;  1PTY A;  3D42 A;  4OHH A;  2B4U A;  2DXP A;  4OHD A;  5K24 A;  2I6M A;  3EAX A;  4D3Q A;  1NNY A;  5K22 A;  2PQ5 A;  3ZMP A;  2G59 A;  3OLR A;  3MOW A;  2H4K A;  4S0G A;  3V0D A;  2ZN7 A;  4GE5 A;  3S3F A;  2P4D A;  4QAP A;  1Q6J A;  3MMJ A;  4JBC A;  4GS0 A;  1NWE A;  3U96 A;  2C7S A;  2OC3 A;  2B4S A;  1GFY A;  2CM3 A;  3BRH A;  1OHD A;  2I6I A;  1G1G A;  2I75 A;  4QBW A;  2AHS A;  1JF7 A;  1EEO A;  2I3R A;  2P6X A;  3M4U A;  1WCH A;  3S4E A;  1I9T A;  4IKC A;  2H4G A;  2CMB A;  2I6J A;  2B4P A;  2QBQ A;  2I6P A;  2HXP A;  2CJZ A;  4TVV A;  2F70 A;  2NLK A;  1NL9 A;  2J16 A;  2B07 A;  1LYV A;  1MKP A;  1YTW A;  2NT2 A;  3QCD A;  4H34 A;  1D5R A;  5KA2 A;  4OHL A;  2B49 A;  2A3K A;  4WOH A;  3QKP A;  2IMG A;  5IBM A;  1NO6 A;  1GWZ A;  2ESB A;  4GWF A;  1Q6M A;  3EU0 A;  3EB1 A;  2I4E A;  4R30 A;  4RI5 A;  1PTV A;  1PTU A;  2H04 A;  3ZM0 A;  3S3H A;  3BLU A;  3D1Q A;  2GP0 A;  3QKQ A;  2J16 B;  4HJQ A;  1NWL A;  3H2X A;  3QCN A;  4NYH A;  2B4O A;  1YWF A;  1G7G A;  1I9S A;  1C87 A;  1YGU A;  1PA9 A;  2R0B A;  3RZ2 A;  2MBC A;  3GXH A;  1RXD A;  2F46 A;  2PI7 A;  3S4O A;  1PH0 A;  1YZ4 A;  4ZRT A;  1XXV A;  2H03 A;  2ZMM A;  2JJD A;  3D9C A;  2CM2 A;  1Q1M A;  2PSZ A;  2FJN A;  2QCJ A;  2QDP A;  3O4T A;  3PS5 A;  1OHC A;  1FPR A;  1U26 A;  2NT7 A;  3QCG A;  3QCK A;  4JMK A;  2QDM A;  3D1O A;  3F41 A;  1AAX A;  5M43 A;  5EHP A;  1VHR A;  2QCT A;  5KAB A;  3QCF A;  3V0J A;  1L8G A;  3LJ8 A;  2QBS A;  3ZV2 A;  1WAX A;  1G1F A;  2HB1 A;  4GE6 A;  2OZ5 A;  1L8K A;  4RKK A;  2HNQ A;  3MOZ A;  3S3E A;  2WGP A;  1C86 A;  2CNH A;  2I4H A;  4ICZ A;  4J51 A;  5LXQ B;  2F6T A;  3OMH A;  1C88 A;  2F6Z A;  5AWX A;  2F6W A;  4PYH A;  5KA9 A;  1Q6P A;  2SHP A;  1X24 A;  2VEU A;  4R0T A;  1FPZ A;  4OHE A;  3QCL A;  4RHG A;  4BJO A;  5K25 A;  1ZCL A;  3QCE A;  2CFV A;  2GJT A;  2HNP A;  2CNI A;  3N0A A;  4WU3 A;  1XBO A;  2AZR A;  1G4U S;  4DGX A;  5KA3 A;  5KAA A;  1I57 A;  3F81 A;  4QUN A;  3CM3 A;  5KA1 A;  5I6V A;  2VEY A;  3I36 A;  4I8N A;  4D3R A;  4D3P A;  1LQF A;  1M3G A;  4JNB A;  3F9B A;  3V0F A;  2F6V A;  5KA7 A;  3AWG A;  1A5Y A;  1Q6S A;  1YN9 A;  3CWE A;  1U25 A;  2F6F A;  1PTT A;  1ONY A;  4AZ1 A;  1KAK A;  5K9W A;  4JMJ A;  4ERC A;  4KI9 A;  2QBP A;  4BPC A;  1SUG A;  4ZI4 A;  3QCC A;  1JLN A;  3I7Z A;  2I1Y A;  3V0E A;  5K23 A;  1RPM A;  1C83 A;  5IBS A;  2B3O A;  1C85 A;  3A5K A;  2I6O A;  2FH7 A;  3NME A;  2F6Y A;  2HC1 A;  2I4G A;  2BIJ A;  4WU2 A;  3RO1 A;  4GRY A;  1XXP A;  2Y2F A;  5MMZ B;  4QBE A;  1OHE A;  4NWG A;  4GFU A;  3S3K A;  1T48 A;  3EMU A;  3A5J A;  1OES A;  3SME A;  5KAD A;  1YFO A;  2HCM A;  5KA8 A;  2A8B A;  2H02 A;  5BZZ A;  2PT0 A;  2VEV A;  1YTS A;  1WRM A;  3ZM1 A;  5KA4 A;  3QCM A;  1NZ7 A;  4GRZ A;  3QCJ A;  1ZC0 A;  4GFV A;  4DGP A;  2C46 A;  3BLT A;  1LAR A;  2NTA A;  1BZJ A;  1OEV A;  5GTJ A;  2HY3 A;  2VEX A;  1T49 A;  2BV5 A;  2CM7 A;  2QDC A;  3AWF A;  1ZCK A;  3O4S A;  1OET A;  2I3U A;  1G4W R;  4B04 A;  1OEO X;  4WTY A;  3V0G A;  3AWE A;  2Q47 A;  3QCI A;  4RH5 A;  1QZ0 A;  3QCB A;  4HJP A;  2CNF A;  5K9V A;  2BGE A;  2I5X A;  2PBN A;  1PYN A;  1Q6T A;  2M3V A;  2BZL A;  2OUD A;  4OHI A;  2F71 A;  5EHR A;  4KYQ A;  3D44 A;  1J4X A;  1U24 A;  2VEW A;  1OEM X;  3QCH A;  3ZMQ A;  3B7O A;  4Y2E A;  2GWO A;  4QAH A;  1V3A A;  4YR8 B;  1FQ1 A;  3SR9 A;  1ONZ A;  2CNG A;  4YAA A;  5BX1 A;  4NX8 A;  2HC2 A;  4KYR A;  5J8R A;  5KA0 A;  3GXG A;  1G1H A;  2CNE A;  1QXK A;  3F99 A;  3RGO A;  4RH9 A;  1KAV A;  3RGQ A;  4ZN5 A;  2PA5 A;  2YDU A;  1YPT A;  1BZC A;  5BZX A;  3V0I A;  4Z6B A;  4PVG A; 
#chains in the Genus database with same CATH topology
 1ZZW A;  2CMC A;  2CMA A;  1R6H A;  1YTN A;  2Y96 A;  2Q05 A;  2HVL A;  4RDD A;  4NND A;  2RF6 A;  1Q6N A;  4UAG A;  3BM8 A;  4H1O A;  3I80 A;  2QEP A;  5HDE A;  1BZH A;  2J17 A;  3O4U A;  4GE2 A;  1XRI A;  1ECV A;  3ZM3 A;  2NV5 A;  4R0S A;  1YGR A;  2CM8 A;  2H4V A;  3EZZ A;  2G6Z A;  4MBB A;  2UAG A;  3D1H A;  4NWF A;  1P15 A;  1XM2 A;  1E0D A;  2NZ6 A;  5BUG A;  4RI4 A;  2XPC A;  3V0H A;  1PA1 A;  1EEN A;  1G7F A;  2I42 A;  1OEU A;  3O5X A;  5KAC A;  4HRF A;  4Y14 A;  3ZM2 A;  2OOQ A;  2E0T A;  3O3L A;  1PXH A;  2X5O A;  1T4J A;  2WTZ A;  3F9A A;  4QUM A;  2FJM A;  2BGD A;  2QBR A;  1C84 A;  1PTY A;  2JFH A;  3D42 A;  3MVN A;  2B4U A;  4OHH A;  2DXP A;  4OHD A;  5K24 A;  2I6M A;  3EAX A;  3N2A A;  4D3Q A;  1NNY A;  5K22 A;  2PQ5 A;  3ZMP A;  2G59 A;  3OLR A;  3MOW A;  2H4K A;  4S0G A;  3V0D A;  2ZN7 A;  4GE5 A;  3S3F A;  2P4D A;  4QAP A;  1Q6J A;  3PYZ A;  3MMJ A;  2XJA A;  4JBC A;  4GS0 A;  1NWE A;  3U96 A;  2C7S A;  2OC3 A;  2B4S A;  1GFY A;  2CM3 A;  3BRH A;  1OHD A;  2GC6 A;  2I6I A;  1G1G A;  2I75 A;  4QBW A;  2AHS A;  1JF7 A;  2AM1 A;  1EEO A;  2I3R A;  2P6X A;  2WJP A;  2Y67 A;  3M4U A;  1WCH A;  3S4E A;  1I9T A;  4IKC A;  2H4G A;  2CMB A;  2I6J A;  2B4P A;  2QBQ A;  3ZM6 A;  3ZM5 A;  2I6P A;  2HXP A;  4BUB A;  2CJZ A;  4TVV A;  2F70 A;  2NLK A;  1NL9 A;  2J16 A;  4HV4 A;  2B07 A;  1LYV A;  1MKP A;  1YTW A;  2NT2 A;  3QCD A;  4H34 A;  1D5R A;  2Y66 A;  2Y1O A;  5KA2 A;  1UAG A;  1W7K A;  4OHL A;  2B49 A;  1JBV A;  2A3K A;  3NRS A;  4WOH A;  3QKP A;  2IMG A;  5IBM A;  4CVM A;  1NO6 A;  1GWZ A;  2ESB A;  4GWF A;  1Q6M A;  3EU0 A;  3EB1 A;  2I4E A;  4R30 A;  4RI5 A;  1PTV A;  1PTU A;  2H04 A;  3ZM0 A;  3S3H A;  3BLU A;  3D1Q A;  2GP0 A;  3QKQ A;  2J16 B;  4HJQ A;  1NWL A;  3H2X A;  3QCN A;  2VOR A;  4NYH A;  2B4O A;  1YWF A;  1G7G A;  1I9S A;  1C87 A;  1YGU A;  1PA9 A;  2R0B A;  3RZ2 A;  2MBC A;  3GXH A;  1RXD A;  2F46 A;  2PI7 A;  3S4O A;  1PH0 A;  1YZ4 A;  4ZRT A;  1XXV A;  1GG4 A;  2H03 A;  2ZMM A;  2JJD A;  3D9C A;  2CM2 A;  1Q1M A;  2PSZ A;  2FJN A;  2QCJ A;  2QDP A;  3O4T A;  3PS5 A;  1OHC A;  1FPR A;  1U26 A;  2NT7 A;  3QCG A;  3QCK A;  4JMK A;  2QDM A;  3D1O A;  4CVL A;  3F41 A;  1AAX A;  5M43 A;  5EHP A;  1VHR A;  2QCT A;  5KAB A;  3QCF A;  3V0J A;  1L8G A;  3LJ8 A;  2QBS A;  3ZV2 A;  1WAX A;  1G1F A;  2HB1 A;  4GE6 A;  2OZ5 A;  1L8K A;  4RKK A;  2HNQ A;  1J6U A;  3MOZ A;  4C12 A;  3S3E A;  2WGP A;  1C86 A;  2CNH A;  2I4H A;  4ICZ A;  2JFG A;  4J51 A;  5LXQ B;  2F6T A;  3OMH A;  1C88 A;  2F6Z A;  5AWX A;  2F6W A;  4PYH A;  5KA9 A;  1Q6P A;  2SHP A;  1X24 A;  2GC5 A;  2VEU A;  3QCZ A;  4R0T A;  1FPZ A;  4OHE A;  2Y68 A;  3QCL A;  4RHG A;  4BJO A;  5K25 A;  1ZCL A;  3QCE A;  4QF5 A;  2CFV A;  2GJT A;  2HNP A;  2CNI A;  3N0A A;  5A5F A;  4WU3 A;  1XBO A;  2AZR A;  1G4U S;  4DGX A;  5KA3 A;  5KAA A;  2GCA A;  1I57 A;  3F81 A;  4QUN A;  3CM3 A;  5KA1 A;  5I6V A;  2VEY A;  3I36 A;  4I8N A;  4D3R A;  4D3P A;  1LQF A;  1M3G A;  4JNB A;  3F9B A;  3V0F A;  2F6V A;  5KA7 A;  3AWG A;  1A5Y A;  1Q6S A;  1YN9 A;  3CWE A;  1U25 A;  2F6F A;  1PTT A;  1ONY A;  4C13 A;  3UAG A;  4AZ1 A;  1KAK A;  5K9W A;  4JMJ A;  4ERC A;  4KI9 A;  2QBP A;  4BPC A;  1SUG A;  4ZI4 A;  3QCC A;  1JLN A;  3I7Z A;  2I1Y A;  3V0E A;  5K23 A;  1RPM A;  1C83 A;  5IBS A;  2B3O A;  1C85 A;  3A5K A;  2I6O A;  2FH7 A;  3NME A;  2F6Y A;  2HC1 A;  2I4G A;  2BIJ A;  3HN7 A;  2UUO A;  4WU2 A;  3RO1 A;  4GRY A;  1XXP A;  2Y2F A;  5MMZ B;  4QBE A;  1OHE A;  4NWG A;  4GFU A;  3S3K A;  1E8C A;  1T48 A;  3EMU A;  3A5J A;  4ZIY A;  1OES A;  3SME A;  3ZL8 A;  5KAD A;  1YFO A;  2HCM A;  5KA8 A;  2A8B A;  2H02 A;  5BZZ A;  2PT0 A;  2VEV A;  1YTS A;  1WRM A;  3ZM1 A;  5KA4 A;  3QCM A;  1NZ7 A;  4GRZ A;  3LK7 A;  1EEH A;  3QCJ A;  1ZC0 A;  4GFV A;  4DGP A;  2C46 A;  3BLT A;  1LAR A;  2NTA A;  1BZJ A;  1OEV A;  5GTJ A;  2HY3 A;  4CVK A;  2VEX A;  1GQY A;  1T49 A;  2BV5 A;  2CM7 A;  2QDC A;  3AWF A;  1ZCK A;  3O4S A;  1O5Z A;  1OET A;  2I3U A;  1G4W R;  4B04 A;  4BUC A;  1OEO X;  4WTY A;  3V0G A;  3AWE A;  2Q47 A;  3QCI A;  4RH5 A;  1QZ0 A;  3QCB A;  4HJP A;  2CNF A;  5K9V A;  2BGE A;  2I5X A;  5A5E A;  2PBN A;  1PYN A;  1Q6T A;  2F00 A;  2M3V A;  2BZL A;  2OUD A;  4OHI A;  2F71 A;  4QDI A;  5EHR A;  4KYQ A;  3D44 A;  1J4X A;  1U24 A;  2VEW A;  2AM2 A;  1OEM X;  3QCH A;  3ZMQ A;  3B7O A;  4Y2E A;  2GWO A;  4QAH A;  2VOS A;  2VTE A;  1V3A A;  4YR8 B;  1FQ1 A;  3SR9 A;  1FGS A;  1ONZ A;  1P3D A;  2CNG A;  4YAA A;  2GCB A;  5BX1 A;  4NX8 A;  2HC2 A;  4KYR A;  5J8R A;  5KA0 A;  1P31 A;  3GXG A;  1G1H A;  2CNE A;  1QXK A;  3F99 A;  3RGO A;  4RH9 A;  1KAV A;  3RGQ A;  4ZN5 A;  2PA5 A;  1JBW A;  2YDU A;  1GQQ A;  2VTD A;  1YPT A;  1BZC A;  2JFF A;  5BZX A;  3V0I A;  4Z6B A;  1W78 A;  2UUP A;  4PVG A; 
#chains in the Genus database with same CATH homology
 1ZZW A;  2CMC A;  2CMA A;  1R6H A;  1YTN A;  2Y96 A;  2Q05 A;  2HVL A;  4RDD A;  4NND A;  2RF6 A;  1Q6N A;  3BM8 A;  4H1O A;  3I80 A;  2QEP A;  5HDE A;  1BZH A;  2J17 A;  3O4U A;  4GE2 A;  1XRI A;  1ECV A;  3ZM3 A;  2NV5 A;  4R0S A;  1YGR A;  2CM8 A;  2H4V A;  3EZZ A;  2G6Z A;  4MBB A;  3D1H A;  4NWF A;  1P15 A;  1XM2 A;  2NZ6 A;  5BUG A;  4RI4 A;  3V0H A;  1PA1 A;  1EEN A;  1G7F A;  2I42 A;  1OEU A;  3O5X A;  5KAC A;  4HRF A;  4Y14 A;  3ZM2 A;  2OOQ A;  2E0T A;  3O3L A;  1PXH A;  1T4J A;  3F9A A;  4QUM A;  2FJM A;  2BGD A;  2QBR A;  1C84 A;  1PTY A;  3D42 A;  4OHH A;  2B4U A;  2DXP A;  4OHD A;  5K24 A;  2I6M A;  3EAX A;  4D3Q A;  1NNY A;  5K22 A;  2PQ5 A;  3ZMP A;  2G59 A;  3OLR A;  3MOW A;  2H4K A;  4S0G A;  3V0D A;  2ZN7 A;  4GE5 A;  3S3F A;  2P4D A;  4QAP A;  1Q6J A;  3MMJ A;  4JBC A;  4GS0 A;  1NWE A;  3U96 A;  2C7S A;  2OC3 A;  2B4S A;  1GFY A;  2CM3 A;  3BRH A;  1OHD A;  2I6I A;  1G1G A;  2I75 A;  4QBW A;  2AHS A;  1JF7 A;  1EEO A;  2I3R A;  2P6X A;  3M4U A;  1WCH A;  3S4E A;  1I9T A;  4IKC A;  2H4G A;  2CMB A;  2I6J A;  2B4P A;  2QBQ A;  2I6P A;  2HXP A;  2CJZ A;  4TVV A;  2F70 A;  2NLK A;  1NL9 A;  2J16 A;  2B07 A;  1LYV A;  1MKP A;  1YTW A;  2NT2 A;  3QCD A;  4H34 A;  1D5R A;  5KA2 A;  4OHL A;  2B49 A;  2A3K A;  4WOH A;  3QKP A;  2IMG A;  5IBM A;  1NO6 A;  1GWZ A;  2ESB A;  4GWF A;  1Q6M A;  3EU0 A;  3EB1 A;  2I4E A;  4R30 A;  4RI5 A;  1PTV A;  1PTU A;  2H04 A;  3ZM0 A;  3S3H A;  3BLU A;  3D1Q A;  2GP0 A;  3QKQ A;  2J16 B;  4HJQ A;  1NWL A;  3H2X A;  3QCN A;  4NYH A;  2B4O A;  1YWF A;  1G7G A;  1I9S A;  1C87 A;  1YGU A;  1PA9 A;  2R0B A;  3RZ2 A;  2MBC A;  3GXH A;  1RXD A;  2F46 A;  2PI7 A;  3S4O A;  1PH0 A;  1YZ4 A;  4ZRT A;  1XXV A;  2H03 A;  2ZMM A;  2JJD A;  3D9C A;  2CM2 A;  1Q1M A;  2PSZ A;  2FJN A;  2QCJ A;  2QDP A;  3O4T A;  3PS5 A;  1OHC A;  1FPR A;  1U26 A;  2NT7 A;  3QCG A;  3QCK A;  4JMK A;  2QDM A;  3D1O A;  3F41 A;  1AAX A;  5M43 A;  5EHP A;  1VHR A;  2QCT A;  5KAB A;  3QCF A;  3V0J A;  1L8G A;  3LJ8 A;  2QBS A;  3ZV2 A;  1WAX A;  1G1F A;  2HB1 A;  4GE6 A;  2OZ5 A;  1L8K A;  4RKK A;  2HNQ A;  3MOZ A;  3S3E A;  2WGP A;  1C86 A;  2CNH A;  2I4H A;  4ICZ A;  4J51 A;  5LXQ B;  2F6T A;  3OMH A;  1C88 A;  2F6Z A;  5AWX A;  2F6W A;  4PYH A;  5KA9 A;  1Q6P A;  2SHP A;  1X24 A;  2VEU A;  4R0T A;  1FPZ A;  4OHE A;  3QCL A;  4RHG A;  4BJO A;  5K25 A;  1ZCL A;  3QCE A;  2CFV A;  2GJT A;  2HNP A;  2CNI A;  3N0A A;  4WU3 A;  1XBO A;  2AZR A;  1G4U S;  4DGX A;  5KA3 A;  5KAA A;  1I57 A;  3F81 A;  4QUN A;  3CM3 A;  5KA1 A;  5I6V A;  2VEY A;  3I36 A;  4I8N A;  4D3R A;  4D3P A;  1LQF A;  1M3G A;  4JNB A;  3F9B A;  3V0F A;  2F6V A;  5KA7 A;  3AWG A;  1A5Y A;  1Q6S A;  1YN9 A;  3CWE A;  1U25 A;  2F6F A;  1PTT A;  1ONY A;  4AZ1 A;  1KAK A;  5K9W A;  4JMJ A;  4ERC A;  4KI9 A;  2QBP A;  4BPC A;  1SUG A;  4ZI4 A;  3QCC A;  1JLN A;  3I7Z A;  2I1Y A;  3V0E A;  5K23 A;  1RPM A;  1C83 A;  5IBS A;  2B3O A;  1C85 A;  3A5K A;  2I6O A;  2FH7 A;  3NME A;  2F6Y A;  2HC1 A;  2I4G A;  2BIJ A;  4WU2 A;  3RO1 A;  4GRY A;  1XXP A;  2Y2F A;  5MMZ B;  4QBE A;  1OHE A;  4NWG A;  4GFU A;  3S3K A;  1T48 A;  3EMU A;  3A5J A;  1OES A;  3SME A;  5KAD A;  1YFO A;  2HCM A;  5KA8 A;  2A8B A;  2H02 A;  5BZZ A;  2PT0 A;  2VEV A;  1YTS A;  1WRM A;  3ZM1 A;  5KA4 A;  3QCM A;  1NZ7 A;  4GRZ A;  3QCJ A;  1ZC0 A;  4GFV A;  4DGP A;  2C46 A;  3BLT A;  1LAR A;  2NTA A;  1BZJ A;  1OEV A;  5GTJ A;  2HY3 A;  2VEX A;  1T49 A;  2BV5 A;  2CM7 A;  2QDC A;  3AWF A;  1ZCK A;  3O4S A;  1OET A;  2I3U A;  1G4W R;  4B04 A;  1OEO X;  4WTY A;  3V0G A;  3AWE A;  2Q47 A;  3QCI A;  4RH5 A;  1QZ0 A;  3QCB A;  4HJP A;  2CNF A;  5K9V A;  2BGE A;  2I5X A;  2PBN A;  1PYN A;  1Q6T A;  2M3V A;  2BZL A;  2OUD A;  4OHI A;  2F71 A;  5EHR A;  4KYQ A;  3D44 A;  1J4X A;  1U24 A;  2VEW A;  1OEM X;  3QCH A;  3ZMQ A;  3B7O A;  4Y2E A;  2GWO A;  4QAH A;  1V3A A;  4YR8 B;  1FQ1 A;  3SR9 A;  1ONZ A;  2CNG A;  4YAA A;  5BX1 A;  4NX8 A;  2HC2 A;  4KYR A;  5J8R A;  5KA0 A;  3GXG A;  1G1H A;  2CNE A;  1QXK A;  3F99 A;  3RGO A;  4RH9 A;  1KAV A;  3RGQ A;  4ZN5 A;  2PA5 A;  2YDU A;  1YPT A;  1BZC A;  5BZX A;  3V0I A;  4Z6B A;  4PVG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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