2M7FA

The c-terminal region of disintegrin modulate its 3d conformation and cooperate with rgd loop in regulating integrins recognitions
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
71
structure length
71
Chain Sequence
GKECDCSSPENPCCDAATCKLRPGAQCGEGLCCEQCKFSRAGKICRIARGDWNDDRCTGQSADCPRNGLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Zinc metalloproteinase/disintegrin
publication title The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins
rcsb
source organism Calloselasma rhodostoma
total genus 6
structure length 71
sequence length 71
ec nomenclature ec 3.4.24.-:
pdb deposition date 2013-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.70.10 Few Secondary Structures Irregular Echistatin Disintegrin domain 2m7fA00
2W9WA 1FVLA 4M4CA 2W9OA 1TEJA 1Z1XA 2ECHA 1L3XA 4R5RA 1RMRA 2PJIA 1N4YA 1TEJB 2PJGA 1RO3A 1J2LA 4R5UA 2M7FA 2M7HA 1MPZA 1Q7IA 3C05A 2M75A 2W9UA 2LJVA 2MOP1 3C05B 2MP51 3G5CA 1Q7JA 3UCIA 4RQGA 2PJFA 2W9VA
chains in the Genus database with same CATH superfamily
2W9WA 1FVLA 4M4CA 2W9OA 1TEJA 1Z1XA 2ECHA 1L3XA 4R5RA 1RMRA 2PJIA 1N4YA 1TEJB 2PJGA 1RO3A 1J2LA 4R5UA 2M7FA 2M7HA 1MPZA 1Q7IA 3C05A 2M75A 2W9UA 2LJVA 2MOP1 3C05B 2MP51 3G5CA 1Q7JA 3UCIA 4RQGA 2PJFA 2W9VA
chains in the Genus database with same CATH topology
2W9WA 1FVLA 4M4CA 2W9OA 1TEJA 1Z1XA 2ECHA 1L3XA 4R5RA 1RMRA 2PJIA 1N4YA 1TEJB 2PJGA 1RO3A 1J2LA 4R5UA 2M7FA 2M7HA 1MPZA 1Q7IA 3C05A 2M75A 2W9UA 2LJVA 2MOP1 3C05B 2MP51 3G5CA 1Q7JA 3UCIA 4RQGA 2PJFA 2W9VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W9W A;  1FVL A;  4M4C A;  2W9O A;  1TEJ A;  1Z1X A;  2ECH A;  1L3X A;  4R5R A;  1RMR A;  2PJI A;  1N4Y A;  1TEJ B;  2PJG A;  1RO3 A;  1J2L A;  4R5U A;  2M7F A;  2M7H A;  1MPZ A;  1Q7I A;  3C05 A;  2M75 A;  2W9U A;  2LJV A;  2MOP 1;  3C05 B;  2MP5 1;  3G5C A;  1Q7J A;  3UCI A;  4RQG A;  2PJF A;  2W9V A; 
#chains in the Genus database with same CATH topology
 2W9W A;  1FVL A;  4M4C A;  2W9O A;  1TEJ A;  1Z1X A;  2ECH A;  1L3X A;  4R5R A;  1RMR A;  2PJI A;  1N4Y A;  1TEJ B;  2PJG A;  1RO3 A;  1J2L A;  4R5U A;  2M7F A;  2M7H A;  1MPZ A;  1Q7I A;  3C05 A;  2M75 A;  2W9U A;  2LJV A;  2MOP 1;  3C05 B;  2MP5 1;  3G5C A;  1Q7J A;  3UCI A;  4RQG A;  2PJF A;  2W9V A; 
#chains in the Genus database with same CATH homology
 2W9W A;  1FVL A;  4M4C A;  2W9O A;  1TEJ A;  1Z1X A;  2ECH A;  1L3X A;  4R5R A;  1RMR A;  2PJI A;  1N4Y A;  1TEJ B;  2PJG A;  1RO3 A;  1J2L A;  4R5U A;  2M7F A;  2M7H A;  1MPZ A;  1Q7I A;  3C05 A;  2M75 A;  2W9U A;  2LJV A;  2MOP 1;  3C05 B;  2MP5 1;  3G5C A;  1Q7J A;  3UCI A;  4RQG A;  2PJF A;  2W9V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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