4R5UA

Crystal structure of rhodostomin r46e mutant
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
64
structure length
64
Chain Sequence
CDCSSPENPCCDAATCKLRPGAQCGEGLCCEQCKFSRAGKICEIPRGDMPDDRCTGQSADCPRY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Disintegrin rhodostomin
publication title Effects of the regions adjacent to the RGD motif in disintegrins on their inhibitory activities and structures
rcsb
source organism Calloselasma rhodostoma
total genus 12
structure length 64
sequence length 64
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-08-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.70.10 Few Secondary Structures Irregular Echistatin Disintegrin domain 4r5uA00
2PJIA 4R5UA 1TEJA 3G5CA 1RO3A 1TEJB 2W9VA 2M7FA 2M7HA 2LJVA 2W9OA 2W9UA 4R5RA 1L3XA 1Z1XA 1Q7JA 2MP51 2ECHA 2M75A 4RQGA 1MPZA 1FVLA 4M4CA 3C05A 1N4YA 3C05B 2MOP1 1J2LA 2PJGA 3UCIA 2W9WA 2PJFA 1RMRA 1Q7IA
chains in the Genus database with same CATH superfamily
2PJIA 4R5UA 1TEJA 3G5CA 1RO3A 1TEJB 2W9VA 2M7FA 2M7HA 2LJVA 2W9OA 2W9UA 4R5RA 1L3XA 1Z1XA 1Q7JA 2MP51 2ECHA 2M75A 4RQGA 1MPZA 1FVLA 4M4CA 3C05A 1N4YA 3C05B 2MOP1 1J2LA 2PJGA 3UCIA 2W9WA 2PJFA 1RMRA 1Q7IA
chains in the Genus database with same CATH topology
2PJIA 4R5UA 1TEJA 3G5CA 1RO3A 1TEJB 2W9VA 2M7FA 2M7HA 2LJVA 2W9OA 2W9UA 4R5RA 1L3XA 1Z1XA 1Q7JA 2MP51 2ECHA 2M75A 4RQGA 1MPZA 1FVLA 4M4CA 3C05A 1N4YA 3C05B 2MOP1 1J2LA 2PJGA 3UCIA 2W9WA 2PJFA 1RMRA 1Q7IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PJI A;  4R5U A;  1TEJ A;  3G5C A;  1RO3 A;  1TEJ B;  2W9V A;  2M7F A;  2M7H A;  2LJV A;  2W9O A;  2W9U A;  4R5R A;  1L3X A;  1Z1X A;  1Q7J A;  2MP5 1;  2ECH A;  2M75 A;  4RQG A;  1MPZ A;  1FVL A;  4M4C A;  3C05 A;  1N4Y A;  3C05 B;  2MOP 1;  1J2L A;  2PJG A;  3UCI A;  2W9W A;  2PJF A;  1RMR A;  1Q7I A; 
#chains in the Genus database with same CATH topology
 2PJI A;  4R5U A;  1TEJ A;  3G5C A;  1RO3 A;  1TEJ B;  2W9V A;  2M7F A;  2M7H A;  2LJV A;  2W9O A;  2W9U A;  4R5R A;  1L3X A;  1Z1X A;  1Q7J A;  2MP5 1;  2ECH A;  2M75 A;  4RQG A;  1MPZ A;  1FVL A;  4M4C A;  3C05 A;  1N4Y A;  3C05 B;  2MOP 1;  1J2L A;  2PJG A;  3UCI A;  2W9W A;  2PJF A;  1RMR A;  1Q7I A; 
#chains in the Genus database with same CATH homology
 2PJI A;  4R5U A;  1TEJ A;  3G5C A;  1RO3 A;  1TEJ B;  2W9V A;  2M7F A;  2M7H A;  2LJV A;  2W9O A;  2W9U A;  4R5R A;  1L3X A;  1Z1X A;  1Q7J A;  2MP5 1;  2ECH A;  2M75 A;  4RQG A;  1MPZ A;  1FVL A;  4M4C A;  3C05 A;  1N4Y A;  3C05 B;  2MOP 1;  1J2L A;  2PJG A;  3UCI A;  2W9W A;  2PJF A;  1RMR A;  1Q7I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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