2QJCA

Crystal structure of a putative diadenosine tetraphosphatase
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
242
structure length
222
Chain Sequence
YANVVTLPNVTGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGAYSVLGNHDAKLLKLVKKLSLAPLAQSIPTDVETYLSQLPHIIRIPAHNVMVAHAGLHPQRPVDRQYEDEVTTMRNLIEKVTLTATEETNDGGKPWASMWRGPETVVFGHDARRGLQEQYKPLAIGLDSRCVYGGRLSAAVFPGGCIISVPGWNG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Diadenosine tetraphosphatase, putative
publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
source organism Trypanosoma brucei
total genus 63
structure length 222
sequence length 242
ec nomenclature ec 3.6.1.41: Bis(5'-nucleosyl)-tetraphosphatase (symmetrical).
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2qjcA00
3ZTVA 1S95A 1KBPA 4ORBA 2R17A 1XM7A 1AUIA 3K7VC 3ZU0A 5JJTA 2DFJA 4H1YP 1U32A 1XZWA 3IVDA 3CK2A 3IB7A 3H64A 1MF8A 3N5UA 2NXFA 4H2BA 2Z06A 1S70A 3H62B 5HPEA 3T1IA 3HVQA 4J6OA 3C5WC 4O24A 3P71C 3H63A 5F3WA 2HYOA 1HO5A 1S8EA 3EGGA 3RL5A 3THNA 5J28A 4O43A 4H2FA 2P6BA 3FGAC 3DSCA 3DW8C 3H68A 1Z2WA 1T70A 1UTEA 4WWLA 4MP0A 4V0WA 3THOB 3LL8A 3GVEA 2IE3C 4LACC 1II7A 1FJMA 2BDXA 2A22A 3ICFA 3QFMA 4H2IA 4M0VA 2CV9A 4F0ZA 4ORCA 3H69A 4I5NC 1QHWA 2WDEA 4DT2A 4TUGA 3QFOA 4DSYA 2NYLC 4MOVA 1W24A 5IOHA 3H60A 4O5GA 4FBKA 4MOYA 4O4KA 4NZVA 3RQZA 4UT3B 4OR9A 1QFCA 3H61A 2IE4C 3RL4A 1OI8A 4FBWA 1USHA 4ORAA 4I5LC 5C1VA 4FBQA 2O8GA 4IL1A 3PSOA 4KBPA 4G9JA 2HY1A 4UT2A 2HYPA 4H2GA 4B2OA 1M63A 3C9FA 5B8IA 3V4YA 1HPUA 4DHLA 4ZVZA 4LTYA 5JPFA 4YKEA 1NNWA 1OIEA 3IB8A 3H67A 1S3NA 3QFNA 5GTUA 4TUIA 4KKZA 5INBA 1Z2XA 2QJCA 1WAO1 1JK7A 3KBPA 2WDDA 3E7AA 1OIDA 3QG5C 3K7WC 1G5BA 1V73A 4H1SA 4UWQA 1WARA 4Q7FA 5DNYA 2BQ8X 2XMOA 1IT6A 2NYMC 2WDFA 2GJUA 4UT3A 2Q8UA 3PSNA 2ZBMA 4IYPC 3H66A 1S3MA 4LU9A 2Z72A 3QFKA 2WDCA 4XPNA 4HD0A 2QFPA 2JOGA 3E7BA 2KKNA 2Z1AA 4ZX2A 2AHDA 4FCXA 4V0VA 1UF3A 4JA9A 3DSDA 1TCOA 2USHA 3IVEA 3AV0A 3TGHA 1S3LA 1SU1A 2QFRA 5JPEA 3JYFA 3AUZA 2YVTA 2NPPC 1HP1A 4JA7A 4V0XA 3EGHA 1T71A 2O8AA 5EQVA 3RL3A 2BCDA 2IAEC
chains in the Genus database with same CATH superfamily
3ZTVA 1S95A 1KBPA 4ORBA 2R17A 1XM7A 1AUIA 3K7VC 3ZU0A 5JJTA 2DFJA 4H1YP 1U32A 1XZWA 3IVDA 3CK2A 3IB7A 3H64A 1MF8A 3N5UA 2ZOAA 2NXFA 4H2BA 2Z06A 1S70A 3H62B 5HPEA 3T1IA 3HVQA 4J6OA 3C5WC 4O24A 3P71C 3H63A 5F3WA 2HYOA 1HO5A 1S8EA 3EGGA 3RL5A 3THNA 5J28A 4O43A 4H2FA 2P6BA 3FGAC 3DSCA 3DW8C 3H68A 1Z2WA 1T70A 1UTEA 4WWLA 4MP0A 4V0WA 3THOB 3LL8A 3GVEA 2IE3C 3D03A 4LACC 1II7A 1FJMA 2BDXA 2ZO9B 2A22A 3ICFA 3QFMA 4H2IA 4M0VA 2CV9A 4F0ZA 4ORCA 3H69A 4I5NC 1QHWA 2WDEA 4DT2A 4TUGA 3QFOA 4DSYA 2NYLC 4MOVA 1W24A 5IOHA 3H60A 4O5GA 4FBKA 4MOYA 4O4KA 4NZVA 3RQZA 4UT3B 4OR9A 1QFCA 3H61A 2IE4C 3RL4A 3E0JA 1OI8A 4FBWA 1USHA 4ORAA 4I5LC 5C1VA 4FBQA 2O8GA 4IL1A 3PSOA 4KBPA 4G9JA 2HY1A 2YEQA 4UT2A 2HYPA 4H2GA 4B2OA 1M63A 3C9FA 5B8IA 3V4YA 1HPUA 4DHLA 4ZVZA 4LTYA 5JPFA 4YKEA 1NNWA 1OIEA 3IB8A 3H67A 1S3NA 3QFNA 5GTUA 4TUIA 4KKZA 5INBA 1Z2XA 2QJCA 1WAO1 1JK7A 3KBPA 2WDDA 3E7AA 1OIDA 3QG5C 3K7WC 3FLOA 1G5BA 1V73A 4H1SA 4UWQA 1WARA 4Q7FA 5DNYA 2BQ8X 2XMOA 1IT6A 2NYMC 2WDFA 2GJUA 4UT3A 2Q8UA 3PSNA 2ZBMA 4IYPC 3H66A 1S3MA 4LU9A 2Z72A 3QFKA 2WDCA 4XPNA 2DXNA 4HD0A 2QFPA 2JOGA 3E7BA 2DXLA 2KKNA 2Z1AA 4ZX2A 2AHDA 4FCXA 4V0VA 1UF3A 4JA9A 3DSDA 1TCOA 2USHA 3IVEA 3AV0A 3TGHA 1S3LA 1SU1A 2QFRA 5JPEA 3JYFA 3AUZA 2YVTA 2NPPC 1HP1A 4JA7A 4V0XA 3EGHA 1T71A 2O8AA 5EQVA 3RL3A 2BCDA 2IAEC
chains in the Genus database with same CATH topology
3ZTVA 1S95A 1KBPA 4ORBA 2R17A 1XM7A 1AUIA 3K7VC 3ZU0A 5JJTA 2DFJA 4H1YP 1U32A 1XZWA 3IVDA 3CK2A 3IB7A 3H64A 1MF8A 3N5UA 2ZOAA 2NXFA 4H2BA 2Z06A 1S70A 3H62B 5HPEA 3T1IA 3HVQA 4J6OA 3C5WC 4O24A 3P71C 3H63A 5F3WA 2HYOA 1HO5A 1S8EA 3EGGA 3RL5A 3THNA 5J28A 4O43A 4H2FA 2P6BA 3FGAC 3DSCA 3DW8C 3H68A 1Z2WA 1T70A 1UTEA 4WWLA 4MP0A 4V0WA 3THOB 3LL8A 3GVEA 2IE3C 3D03A 4LACC 1II7A 1FJMA 2BDXA 2ZO9B 2A22A 3ICFA 3QFMA 4H2IA 4M0VA 2CV9A 4F0ZA 4ORCA 3H69A 4I5NC 1QHWA 2WDEA 4DT2A 4TUGA 3QFOA 4DSYA 2NYLC 4MOVA 1W24A 5IOHA 3H60A 4O5GA 4FBKA 4MOYA 4O4KA 4NZVA 3RQZA 4UT3B 4OR9A 1QFCA 3H61A 2IE4C 3RL4A 3E0JA 1OI8A 4FBWA 1USHA 4ORAA 4I5LC 5C1VA 4FBQA 2O8GA 4IL1A 3PSOA 4KBPA 4G9JA 2HY1A 2YEQA 4UT2A 2HYPA 4H2GA 4B2OA 1M63A 3C9FA 5B8IA 3V4YA 1HPUA 4DHLA 4ZVZA 4LTYA 5JPFA 4YKEA 1NNWA 1OIEA 3IB8A 3H67A 1S3NA 3QFNA 5GTUA 4TUIA 4KKZA 5INBA 1Z2XA 2QJCA 1WAO1 1JK7A 3KBPA 2WDDA 3E7AA 1OIDA 3QG5C 3K7WC 3FLOA 1G5BA 1V73A 4H1SA 4UWQA 1WARA 4Q7FA 5DNYA 2BQ8X 2XMOA 1IT6A 2NYMC 2WDFA 2GJUA 4UT3A 2Q8UA 3PSNA 2ZBMA 4IYPC 3H66A 1S3MA 4LU9A 2Z72A 3QFKA 2WDCA 4XPNA 2DXNA 4HD0A 2QFPA 2JOGA 3E7BA 2DXLA 2KKNA 2Z1AA 4ZX2A 2AHDA 4FCXA 4V0VA 1UF3A 4JA9A 3DSDA 1TCOA 2USHA 3IVEA 3AV0A 3TGHA 1S3LA 1SU1A 2QFRA 5JPEA 3JYFA 3AUZA 2YVTA 2NPPC 1HP1A 4JA7A 4V0XA 3EGHA 1T71A 2O8AA 5EQVA 3RL3A 2BCDA 2IAEC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3ZTV A;  1S95 A;  1KBP A;  4ORB A;  2R17 A;  1XM7 A;  1AUI A;  3K7V C;  3ZU0 A;  5JJT A;  2DFJ A;  4H1Y P;  1U32 A;  1XZW A;  3IVD A;  3CK2 A;  3IB7 A;  3H64 A;  1MF8 A;  3N5U A;  2NXF A;  4H2B A;  2Z06 A;  1S70 A;  3H62 B;  5HPE A;  3T1I A;  3HVQ A;  4J6O A;  3C5W C;  4O24 A;  3P71 C;  3H63 A;  5F3W A;  2HYO A;  1HO5 A;  1S8E A;  3EGG A;  3RL5 A;  3THN A;  5J28 A;  4O43 A;  4H2F A;  2P6B A;  3FGA C;  3DSC A;  3DW8 C;  3H68 A;  1Z2W A;  1T70 A;  1UTE A;  4WWL A;  4MP0 A;  4V0W A;  3THO B;  3LL8 A;  3GVE A;  2IE3 C;  4LAC C;  1II7 A;  1FJM A;  2BDX A;  2A22 A;  3ICF A;  3QFM A;  4H2I A;  4M0V A;  2CV9 A;  4F0Z A;  4ORC A;  3H69 A;  4I5N C;  1QHW A;  2WDE A;  4DT2 A;  4TUG A;  3QFO A;  4DSY A;  2NYL C;  4MOV A;  1W24 A;  5IOH A;  3H60 A;  4O5G A;  4FBK A;  4MOY A;  4O4K A;  4NZV A;  3RQZ A;  4UT3 B;  4OR9 A;  1QFC A;  3H61 A;  2IE4 C;  3RL4 A;  1OI8 A;  4FBW A;  1USH A;  4ORA A;  4I5L C;  5C1V A;  4FBQ A;  2O8G A;  4IL1 A;  3PSO A;  4KBP A;  4G9J A;  2HY1 A;  4UT2 A;  2HYP A;  4H2G A;  4B2O A;  1M63 A;  3C9F A;  5B8I A;  3V4Y A;  1HPU A;  4DHL A;  4ZVZ A;  4LTY A;  5JPF A;  4YKE A;  1NNW A;  1OIE A;  3IB8 A;  3H67 A;  1S3N A;  3QFN A;  5GTU A;  4TUI A;  4KKZ A;  5INB A;  1Z2X A;  2QJC A;  1WAO 1;  1JK7 A;  3KBP A;  2WDD A;  3E7A A;  1OID A;  3QG5 C;  3K7W C;  1G5B A;  1V73 A;  4H1S A;  4UWQ A;  1WAR A;  4Q7F A;  5DNY A;  2BQ8 X;  2XMO A;  1IT6 A;  2NYM C;  2WDF A;  2GJU A;  4UT3 A;  2Q8U A;  3PSN A;  2ZBM A;  4IYP C;  3H66 A;  1S3M A;  4LU9 A;  2Z72 A;  3QFK A;  2WDC A;  4XPN A;  4HD0 A;  2QFP A;  2JOG A;  3E7B A;  2KKN A;  2Z1A A;  4ZX2 A;  2AHD A;  4FCX A;  4V0V A;  1UF3 A;  4JA9 A;  3DSD A;  1TCO A;  2USH A;  3IVE A;  3AV0 A;  3TGH A;  1S3L A;  1SU1 A;  2QFR A;  5JPE A;  3JYF A;  3AUZ A;  2YVT A;  2NPP C;  1HP1 A;  4JA7 A;  4V0X A;  3EGH A;  1T71 A;  2O8A A;  5EQV A;  3RL3 A;  2BCD A;  2IAE C; 
#chains in the Genus database with same CATH topology
 3ZTV A;  1S95 A;  1KBP A;  4ORB A;  2R17 A;  1XM7 A;  1AUI A;  3K7V C;  3ZU0 A;  5JJT A;  2DFJ A;  4H1Y P;  1U32 A;  1XZW A;  3IVD A;  3CK2 A;  3IB7 A;  3H64 A;  1MF8 A;  3N5U A;  2ZOA A;  2NXF A;  4H2B A;  2Z06 A;  1S70 A;  3H62 B;  5HPE A;  3T1I A;  3HVQ A;  4J6O A;  3C5W C;  4O24 A;  3P71 C;  3H63 A;  5F3W A;  2HYO A;  1HO5 A;  1S8E A;  3EGG A;  3RL5 A;  3THN A;  5J28 A;  4O43 A;  4H2F A;  2P6B A;  3FGA C;  3DSC A;  3DW8 C;  3H68 A;  1Z2W A;  1T70 A;  1UTE A;  4WWL A;  4MP0 A;  4V0W A;  3THO B;  3LL8 A;  3GVE A;  2IE3 C;  3D03 A;  4LAC C;  1II7 A;  1FJM A;  2BDX A;  2ZO9 B;  2A22 A;  3ICF A;  3QFM A;  4H2I A;  4M0V A;  2CV9 A;  4F0Z A;  4ORC A;  3H69 A;  4I5N C;  1QHW A;  2WDE A;  4DT2 A;  4TUG A;  3QFO A;  4DSY A;  2NYL C;  4MOV A;  1W24 A;  5IOH A;  3H60 A;  4O5G A;  4FBK A;  4MOY A;  4O4K A;  4NZV A;  3RQZ A;  4UT3 B;  4OR9 A;  1QFC A;  3H61 A;  2IE4 C;  3RL4 A;  3E0J A;  1OI8 A;  4FBW A;  1USH A;  4ORA A;  4I5L C;  5C1V A;  4FBQ A;  2O8G A;  4IL1 A;  3PSO A;  4KBP A;  4G9J A;  2HY1 A;  2YEQ A;  4UT2 A;  2HYP A;  4H2G A;  4B2O A;  1M63 A;  3C9F A;  5B8I A;  3V4Y A;  1HPU A;  4DHL A;  4ZVZ A;  4LTY A;  5JPF A;  4YKE A;  1NNW A;  1OIE A;  3IB8 A;  3H67 A;  1S3N A;  3QFN A;  5GTU A;  4TUI A;  4KKZ A;  5INB A;  1Z2X A;  2QJC A;  1WAO 1;  1JK7 A;  3KBP A;  2WDD A;  3E7A A;  1OID A;  3QG5 C;  3K7W C;  3FLO A;  1G5B A;  1V73 A;  4H1S A;  4UWQ A;  1WAR A;  4Q7F A;  5DNY A;  2BQ8 X;  2XMO A;  1IT6 A;  2NYM C;  2WDF A;  2GJU A;  4UT3 A;  2Q8U A;  3PSN A;  2ZBM A;  4IYP C;  3H66 A;  1S3M A;  4LU9 A;  2Z72 A;  3QFK A;  2WDC A;  4XPN A;  2DXN A;  4HD0 A;  2QFP A;  2JOG A;  3E7B A;  2DXL A;  2KKN A;  2Z1A A;  4ZX2 A;  2AHD A;  4FCX A;  4V0V A;  1UF3 A;  4JA9 A;  3DSD A;  1TCO A;  2USH A;  3IVE A;  3AV0 A;  3TGH A;  1S3L A;  1SU1 A;  2QFR A;  5JPE A;  3JYF A;  3AUZ A;  2YVT A;  2NPP C;  1HP1 A;  4JA7 A;  4V0X A;  3EGH A;  1T71 A;  2O8A A;  5EQV A;  3RL3 A;  2BCD A;  2IAE C; 
#chains in the Genus database with same CATH homology
 3ZTV A;  1S95 A;  1KBP A;  4ORB A;  2R17 A;  1XM7 A;  1AUI A;  3K7V C;  3ZU0 A;  5JJT A;  2DFJ A;  4H1Y P;  1U32 A;  1XZW A;  3IVD A;  3CK2 A;  3IB7 A;  3H64 A;  1MF8 A;  3N5U A;  2ZOA A;  2NXF A;  4H2B A;  2Z06 A;  1S70 A;  3H62 B;  5HPE A;  3T1I A;  3HVQ A;  4J6O A;  3C5W C;  4O24 A;  3P71 C;  3H63 A;  5F3W A;  2HYO A;  1HO5 A;  1S8E A;  3EGG A;  3RL5 A;  3THN A;  5J28 A;  4O43 A;  4H2F A;  2P6B A;  3FGA C;  3DSC A;  3DW8 C;  3H68 A;  1Z2W A;  1T70 A;  1UTE A;  4WWL A;  4MP0 A;  4V0W A;  3THO B;  3LL8 A;  3GVE A;  2IE3 C;  3D03 A;  4LAC C;  1II7 A;  1FJM A;  2BDX A;  2ZO9 B;  2A22 A;  3ICF A;  3QFM A;  4H2I A;  4M0V A;  2CV9 A;  4F0Z A;  4ORC A;  3H69 A;  4I5N C;  1QHW A;  2WDE A;  4DT2 A;  4TUG A;  3QFO A;  4DSY A;  2NYL C;  4MOV A;  1W24 A;  5IOH A;  3H60 A;  4O5G A;  4FBK A;  4MOY A;  4O4K A;  4NZV A;  3RQZ A;  4UT3 B;  4OR9 A;  1QFC A;  3H61 A;  2IE4 C;  3RL4 A;  3E0J A;  1OI8 A;  4FBW A;  1USH A;  4ORA A;  4I5L C;  5C1V A;  4FBQ A;  2O8G A;  4IL1 A;  3PSO A;  4KBP A;  4G9J A;  2HY1 A;  2YEQ A;  4UT2 A;  2HYP A;  4H2G A;  4B2O A;  1M63 A;  3C9F A;  5B8I A;  3V4Y A;  1HPU A;  4DHL A;  4ZVZ A;  4LTY A;  5JPF A;  4YKE A;  1NNW A;  1OIE A;  3IB8 A;  3H67 A;  1S3N A;  3QFN A;  5GTU A;  4TUI A;  4KKZ A;  5INB A;  1Z2X A;  2QJC A;  1WAO 1;  1JK7 A;  3KBP A;  2WDD A;  3E7A A;  1OID A;  3QG5 C;  3K7W C;  3FLO A;  1G5B A;  1V73 A;  4H1S A;  4UWQ A;  1WAR A;  4Q7F A;  5DNY A;  2BQ8 X;  2XMO A;  1IT6 A;  2NYM C;  2WDF A;  2GJU A;  4UT3 A;  2Q8U A;  3PSN A;  2ZBM A;  4IYP C;  3H66 A;  1S3M A;  4LU9 A;  2Z72 A;  3QFK A;  2WDC A;  4XPN A;  2DXN A;  4HD0 A;  2QFP A;  2JOG A;  3E7B A;  2DXL A;  2KKN A;  2Z1A A;  4ZX2 A;  2AHD A;  4FCX A;  4V0V A;  1UF3 A;  4JA9 A;  3DSD A;  1TCO A;  2USH A;  3IVE A;  3AV0 A;  3TGH A;  1S3L A;  1SU1 A;  2QFR A;  5JPE A;  3JYF A;  3AUZ A;  2YVT A;  2NPP C;  1HP1 A;  4JA7 A;  4V0X A;  3EGH A;  1T71 A;  2O8A A;  5EQV A;  3RL3 A;  2BCD A;  2IAE C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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