2V5NA

Structure of human igf2r domains 11-12
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
281
structure length
271
Chain Sequence
CQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYNPDFYINICQPLNPMHAVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEIYLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Receptor
molecule keywords CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
publication title Structure and Functional Analysis of the Igf-II/Igf2R Interaction
pubmed doi rcsb
source organism Homo sapiens
total genus 47
structure length 271
sequence length 281
ec nomenclature
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00878 CIMR Cation-independent mannose-6-phosphate receptor repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2v5nA01
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2v5nA02
2RLBA 1SZ0A 2V5NA 2N1HA 2M68A 1GQBA 2KVAA 2L29A 2LLAA 2RL8A 2CNJD 3AIHA 4XQMA 2RL9A 1KEOA 1GP3A 3K41A 2KVBA 2RL7A 3K42A 5IEIA 3K43A 1SYOA 2L2GA 2V5OA 1Q25A 2LVXA 1C39A 3CY4A 1E6FA 1GP0A 2L2AA 2L21A 2M6TA 1M6PA
chains in the Genus database with same CATH superfamily
2RLBA 1SZ0A 2V5NA 2N1HA 2M68A 1GQBA 2KVAA 2L29A 2LLAA 2RL8A 2CNJD 3AIHA 4XQMA 2RL9A 1KEOA 1GP3A 3K41A 2KVBA 2RL7A 3K42A 5IEIA 3K43A 1SYOA 2L2GA 2V5OA 1Q25A 2LVXA 1C39A 3CY4A 1E6FA 1GP0A 2L2AA 2L21A 2M6TA 1M6PA
chains in the Genus database with same CATH topology
2RLBA 1SZ0A 2V5NA 2N1HA 2M68A 1GQBA 2KVAA 2L29A 2LLAA 2RL8A 2CNJD 3AIHA 4XQMA 2RL9A 1KEOA 1GP3A 3K41A 2KVBA 2RL7A 3K42A 5IEIA 3K43A 1SYOA 2L2GA 2V5OA 1Q25A 2LVXA 1C39A 3CY4A 1E6FA 1GP0A 2L2AA 2L21A 2M6TA 1M6PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RLB A;  1SZ0 A;  2V5N A;  2N1H A;  2M68 A;  1GQB A;  2KVA A;  2L29 A;  2LLA A;  2RL8 A;  2CNJ D;  3AIH A;  4XQM A;  2RL9 A;  1KEO A;  1GP3 A;  3K41 A;  2KVB A;  2RL7 A;  3K42 A;  5IEI A;  3K43 A;  1SYO A;  2L2G A;  2V5O A;  1Q25 A;  2LVX A;  1C39 A;  3CY4 A;  1E6F A;  1GP0 A;  2L2A A;  2L21 A;  2M6T A;  1M6P A; 
#chains in the Genus database with same CATH topology
 2RLB A;  1SZ0 A;  2V5N A;  2N1H A;  2M68 A;  1GQB A;  2KVA A;  2L29 A;  2LLA A;  2RL8 A;  2CNJ D;  3AIH A;  4XQM A;  2RL9 A;  1KEO A;  1GP3 A;  3K41 A;  2KVB A;  2RL7 A;  3K42 A;  5IEI A;  3K43 A;  1SYO A;  2L2G A;  2V5O A;  1Q25 A;  2LVX A;  1C39 A;  3CY4 A;  1E6F A;  1GP0 A;  2L2A A;  2L21 A;  2M6T A;  1M6P A; 
#chains in the Genus database with same CATH homology
 2RLB A;  1SZ0 A;  2V5N A;  2N1H A;  2M68 A;  1GQB A;  2KVA A;  2L29 A;  2LLA A;  2RL8 A;  2CNJ D;  3AIH A;  4XQM A;  2RL9 A;  1KEO A;  1GP3 A;  3K41 A;  2KVB A;  2RL7 A;  3K42 A;  5IEI A;  3K43 A;  1SYO A;  2L2G A;  2V5O A;  1Q25 A;  2LVX A;  1C39 A;  3CY4 A;  1E6F A;  1GP0 A;  2L2A A;  2L21 A;  2M6T A;  1M6P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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