3K43A

Crystal structure of scd-mpr mutant e19q/k137m ph 6.5
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
152
structure length
141
Chain Sequence
EKTCDLVGESEKQLALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSECFYLFEMDSSLACS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein transport, sugar binding protein
molecule keywords Cation-dependent mannose-6-phosphate receptor
publication title Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor.
pubmed doi rcsb
source organism Bos taurus
total genus 36
structure length 141
sequence length 152
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-10-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 3k43A00
2KVAA 3AIHA 3CY4A 1M6PA 2RLBA 1E6FA 2L21A 2LVXA 3K42A 2CNJD 2RL9A 1GP0A 1SYOA 5IEIA 2V5NA 2M68A 3K41A 4XQMA 2LLAA 3K43A 2KVBA 2M6TA 1SZ0A 1GP3A 2N1HA 1GQBA 2V5OA 2L29A 2RL7A 1C39A 1KEOA 2L2AA 2L2GA 2RL8A 1Q25A
chains in the Genus database with same CATH superfamily
2KVAA 3AIHA 3CY4A 1M6PA 2RLBA 1E6FA 2L21A 2LVXA 3K42A 2CNJD 2RL9A 1GP0A 1SYOA 5IEIA 2V5NA 2M68A 3K41A 4XQMA 2LLAA 3K43A 2KVBA 2M6TA 1SZ0A 1GP3A 2N1HA 1GQBA 2V5OA 2L29A 2RL7A 1C39A 1KEOA 2L2AA 2L2GA 2RL8A 1Q25A
chains in the Genus database with same CATH topology
2KVAA 3AIHA 3CY4A 1M6PA 2RLBA 1E6FA 2L21A 2LVXA 3K42A 2CNJD 2RL9A 1GP0A 1SYOA 5IEIA 2V5NA 2M68A 3K41A 4XQMA 2LLAA 3K43A 2KVBA 2M6TA 1SZ0A 1GP3A 2N1HA 1GQBA 2V5OA 2L29A 2RL7A 1C39A 1KEOA 2L2AA 2L2GA 2RL8A 1Q25A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KVA A;  3AIH A;  3CY4 A;  1M6P A;  2RLB A;  1E6F A;  2L21 A;  2LVX A;  3K42 A;  2CNJ D;  2RL9 A;  1GP0 A;  1SYO A;  5IEI A;  2V5N A;  2M68 A;  3K41 A;  4XQM A;  2LLA A;  3K43 A;  2KVB A;  2M6T A;  1SZ0 A;  1GP3 A;  2N1H A;  1GQB A;  2V5O A;  2L29 A;  2RL7 A;  1C39 A;  1KEO A;  2L2A A;  2L2G A;  2RL8 A;  1Q25 A; 
#chains in the Genus database with same CATH topology
 2KVA A;  3AIH A;  3CY4 A;  1M6P A;  2RLB A;  1E6F A;  2L21 A;  2LVX A;  3K42 A;  2CNJ D;  2RL9 A;  1GP0 A;  1SYO A;  5IEI A;  2V5N A;  2M68 A;  3K41 A;  4XQM A;  2LLA A;  3K43 A;  2KVB A;  2M6T A;  1SZ0 A;  1GP3 A;  2N1H A;  1GQB A;  2V5O A;  2L29 A;  2RL7 A;  1C39 A;  1KEO A;  2L2A A;  2L2G A;  2RL8 A;  1Q25 A; 
#chains in the Genus database with same CATH homology
 2KVA A;  3AIH A;  3CY4 A;  1M6P A;  2RLB A;  1E6F A;  2L21 A;  2LVX A;  3K42 A;  2CNJ D;  2RL9 A;  1GP0 A;  1SYO A;  5IEI A;  2V5N A;  2M68 A;  3K41 A;  4XQM A;  2LLA A;  3K43 A;  2KVB A;  2M6T A;  1SZ0 A;  1GP3 A;  2N1H A;  1GQB A;  2V5O A;  2L29 A;  2RL7 A;  1C39 A;  1KEO A;  2L2A A;  2L2G A;  2RL8 A;  1Q25 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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