3IT5A

Crystal structure of the lasa virulence factor from pseudomonas aeruginosa
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
182
structure length
182
Chain Sequence
APPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQIQVSNGQQVSADTKLGVYAGNINTALCEGGSSTGPHLHFSLLYNGAFVSLQGASFGPYRINVGTSNYDNDCRRYYFYNQSAGTTHCAFRPLYNPGLAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Protease lasA
publication title Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
pubmed doi rcsb
total genus 46
structure length 182
sequence length 182
chains with identical sequence B, E, G
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01551 Peptidase_M23 Peptidase family M23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.70.10 Mainly Beta Distorted Sandwich Glucose Permease (Domain IIA) Glucose Permease (Domain IIA) 3it5A00
3NYYA 1QWYA 2B0PA 4LXCA 1GLCF 4QP5A 3CSQA 3IT5A 3OURB 2B44A 3SLUA 1O2FA 2B13A 1F3ZA 2GPRA 5B0HA 5KVPA 2MP0B 4ZYBA 1GLEF 1AX3A 1F3GA 4QPBA 2GU1A 3TUFB 1GGRA 3IT7A 4RNYA 4BH5A 1GPRA 3UZ0B 2F3GA 2HSIA 4RNZA 1GLAF 1GLDF 4JBWM 1GLBF
chains in the Genus database with same CATH superfamily
3NYYA 1QWYA 2B0PA 4LXCA 1GLCF 4QP5A 3CSQA 3IT5A 3OURB 2B44A 3SLUA 1O2FA 2B13A 1F3ZA 2GPRA 5B0HA 5KVPA 2MP0B 4ZYBA 1GLEF 1AX3A 1F3GA 4QPBA 2GU1A 3TUFB 1GGRA 3IT7A 4RNYA 4BH5A 1GPRA 3UZ0B 2F3GA 2HSIA 4RNZA 1GLAF 1GLDF 4JBWM 1GLBF
chains in the Genus database with same CATH topology
3NYYA 1QWYA 2B0PA 4LXCA 1GLCF 4QP5A 3CSQA 3IT5A 3OURB 2B44A 3SLUA 1O2FA 2B13A 1F3ZA 2GPRA 5B0HA 5KVPA 2MP0B 4ZYBA 1GLEF 1AX3A 1F3GA 4QPBA 2GU1A 3TUFB 1GGRA 3IT7A 4RNYA 4BH5A 1GPRA 3UZ0B 2F3GA 2HSIA 4RNZA 1GLAF 1GLDF 4JBWM 1GLBF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NYY A;  1QWY A;  2B0P A;  4LXC A;  1GLC F;  4QP5 A;  3CSQ A;  3IT5 A;  3OUR B;  2B44 A;  3SLU A;  1O2F A;  2B13 A;  1F3Z A;  2GPR A;  5B0H A;  5KVP A;  2MP0 B;  4ZYB A;  1GLE F;  1AX3 A;  1F3G A;  4QPB A;  2GU1 A;  3TUF B;  1GGR A;  3IT7 A;  4RNY A;  4BH5 A;  1GPR A;  3UZ0 B;  2F3G A;  2HSI A;  4RNZ A;  1GLA F;  1GLD F;  4JBW M;  1GLB F; 
#chains in the Genus database with same CATH topology
 3NYY A;  1QWY A;  2B0P A;  4LXC A;  1GLC F;  4QP5 A;  3CSQ A;  3IT5 A;  3OUR B;  2B44 A;  3SLU A;  1O2F A;  2B13 A;  1F3Z A;  2GPR A;  5B0H A;  5KVP A;  2MP0 B;  4ZYB A;  1GLE F;  1AX3 A;  1F3G A;  4QPB A;  2GU1 A;  3TUF B;  1GGR A;  3IT7 A;  4RNY A;  4BH5 A;  1GPR A;  3UZ0 B;  2F3G A;  2HSI A;  4RNZ A;  1GLA F;  1GLD F;  4JBW M;  1GLB F; 
#chains in the Genus database with same CATH homology
 3NYY A;  1QWY A;  2B0P A;  4LXC A;  1GLC F;  4QP5 A;  3CSQ A;  3IT5 A;  3OUR B;  2B44 A;  3SLU A;  1O2F A;  2B13 A;  1F3Z A;  2GPR A;  5B0H A;  5KVP A;  2MP0 B;  4ZYB A;  1GLE F;  1AX3 A;  1F3G A;  4QPB A;  2GU1 A;  3TUF B;  1GGR A;  3IT7 A;  4RNY A;  4BH5 A;  1GPR A;  3UZ0 B;  2F3G A;  2HSI A;  4RNZ A;  1GLA F;  1GLD F;  4JBW M;  1GLB F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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