3IT7A

Crystal structure of the lasa virulence factor from pseudomonas aeruginosa
Total Genus 48
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
182
structure length
182
Chain Sequence
APPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQIQVSNGQQVSADTKLGVYAGNINTALCEGGSSTGPHLHFSLLYNGAFVSLQGASFGPYRINVGTSNYDNDCRRYYFYNQSAGTTHCAFRPLYNPGLAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Protease lasA
publication title Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
pubmed doi rcsb
total genus 48
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01551 Peptidase_M23 Peptidase family M23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.70.10 Mainly Beta Distorted Sandwich Glucose Permease (Domain IIA) Glucose Permease (Domain IIA) 3it7A00
1GGRA 2MP0B 3NYYA 1GPRA 3SLUA 1F3GA 3IT5A 5B0HA 3TUFB 1GLEF 2F3GA 4ZYBA 1AX3A 4LXCA 2B0PA 1O2FA 2GPRA 5KVPA 1GLAF 2HSIA 2B13A 3IT7A 1GLCF 1GLDF 4QP5A 4RNYA 4QPBA 2GU1A 2B44A 4JBWM 3UZ0B 4RNZA 1GLBF 3OURB 4BH5A 3CSQA 1F3ZA 1QWYA
chains in the Genus database with same CATH superfamily
1GGRA 2MP0B 3NYYA 1GPRA 3SLUA 1F3GA 3IT5A 5B0HA 3TUFB 1GLEF 2F3GA 4ZYBA 1AX3A 4LXCA 2B0PA 1O2FA 2GPRA 5KVPA 1GLAF 2HSIA 2B13A 3IT7A 1GLCF 1GLDF 4QP5A 4RNYA 4QPBA 2GU1A 2B44A 4JBWM 3UZ0B 4RNZA 1GLBF 3OURB 4BH5A 3CSQA 1F3ZA 1QWYA
chains in the Genus database with same CATH topology
1GGRA 2MP0B 3NYYA 1GPRA 3SLUA 1F3GA 3IT5A 5B0HA 3TUFB 1GLEF 2F3GA 4ZYBA 1AX3A 4LXCA 2B0PA 1O2FA 2GPRA 5KVPA 1GLAF 2HSIA 2B13A 3IT7A 1GLCF 1GLDF 4QP5A 4RNYA 4QPBA 2GU1A 2B44A 4JBWM 3UZ0B 4RNZA 1GLBF 3OURB 4BH5A 3CSQA 1F3ZA 1QWYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GGR A;  2MP0 B;  3NYY A;  1GPR A;  3SLU A;  1F3G A;  3IT5 A;  5B0H A;  3TUF B;  1GLE F;  2F3G A;  4ZYB A;  1AX3 A;  4LXC A;  2B0P A;  1O2F A;  2GPR A;  5KVP A;  1GLA F;  2HSI A;  2B13 A;  3IT7 A;  1GLC F;  1GLD F;  4QP5 A;  4RNY A;  4QPB A;  2GU1 A;  2B44 A;  4JBW M;  3UZ0 B;  4RNZ A;  1GLB F;  3OUR B;  4BH5 A;  3CSQ A;  1F3Z A;  1QWY A; 
#chains in the Genus database with same CATH topology
 1GGR A;  2MP0 B;  3NYY A;  1GPR A;  3SLU A;  1F3G A;  3IT5 A;  5B0H A;  3TUF B;  1GLE F;  2F3G A;  4ZYB A;  1AX3 A;  4LXC A;  2B0P A;  1O2F A;  2GPR A;  5KVP A;  1GLA F;  2HSI A;  2B13 A;  3IT7 A;  1GLC F;  1GLD F;  4QP5 A;  4RNY A;  4QPB A;  2GU1 A;  2B44 A;  4JBW M;  3UZ0 B;  4RNZ A;  1GLB F;  3OUR B;  4BH5 A;  3CSQ A;  1F3Z A;  1QWY A; 
#chains in the Genus database with same CATH homology
 1GGR A;  2MP0 B;  3NYY A;  1GPR A;  3SLU A;  1F3G A;  3IT5 A;  5B0H A;  3TUF B;  1GLE F;  2F3G A;  4ZYB A;  1AX3 A;  4LXC A;  2B0P A;  1O2F A;  2GPR A;  5KVP A;  1GLA F;  2HSI A;  2B13 A;  3IT7 A;  1GLC F;  1GLD F;  4QP5 A;  4RNY A;  4QPB A;  2GU1 A;  2B44 A;  4JBW M;  3UZ0 B;  4RNZ A;  1GLB F;  3OUR B;  4BH5 A;  3CSQ A;  1F3Z A;  1QWY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...