3J7AW

Cryo-em structure of the plasmodium falciparum 80s ribosome bound to the anti-protozoan drug emetine, small subunit
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
108
structure length
95
Chain Sequence
RVRTKTIKRAARQIVEKYYAKLTLDFQINKKITEEVAIIPSKRMKNKVAGFVTHLMKRIQKGPVRGISLKLQEEERERRLDYVEPDTLRMIKSLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome/inhibitor
molecule keywords 18S ribosomal RNA
publication title Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
pubmed doi rcsb
total genus 22
structure length 95
sequence length 108
ec nomenclature
pdb deposition date 2014-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00833 Ribosomal_S17e Ribosomal S17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.60.20 Mainly Alpha Orthogonal Bundle Diphtheria Toxin Repressor; domain 2 Ribosomal protein S17e-like 3j7aW01
3J80R 1RQ6A 3JAMR 5FLXR 5IT9R 5A2QR 3J7AW 3J81R
chains in the Genus database with same CATH superfamily
2HYGD 1U8RA 1FX7A 5FLXR 1G3WA 2F5CA 1XCVA 1DPRA 1FWZA 3R60A 2ISZA 1B1BA 1C0WA 4O6JA 3J80R 2MVTA 2M35A 3A52A 2X98A 1ON2A 1G3TA 1BI3A 3J7AW 3J81R 1F5TA 2EV6A 2HYFA 2MZ4A 4HX8A 2MUNA 1P92A 1RQ6A 2EV5A 2F5FA 2DTRA 3JAMR 1DDNA 2F5EA 2QQ9A 1ON1A 4O5VA 2QQAA 2QQBA 1BI2A 2TDXA 2EV0A 4HX7A 1BI0A 5IT9R 1G3SA 3GLXA 5A2QR 3R61A 2H09A 1G3YA 4HV5A 4HV6A 2F5DA 1BI1A 4HX4A 2P0TA
chains in the Genus database with same CATH topology
3J80R 1RQ6A 3JAMR 5FLXR 5IT9R 5A2QR 3J7AW 3J81R
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3J80 R;  1RQ6 A;  3JAM R;  5FLX R;  5IT9 R;  5A2Q R;  3J7A W;  3J81 R; 
#chains in the Genus database with same CATH topology
 2HYG D;  1U8R A;  1FX7 A;  5FLX R;  1G3W A;  2F5C A;  1XCV A;  1DPR A;  1FWZ A;  3R60 A;  2ISZ A;  1B1B A;  1C0W A;  4O6J A;  3J80 R;  2MVT A;  2M35 A;  3A52 A;  2X98 A;  1ON2 A;  1G3T A;  1BI3 A;  3J7A W;  3J81 R;  1F5T A;  2EV6 A;  2HYF A;  2MZ4 A;  4HX8 A;  2MUN A;  1P92 A;  1RQ6 A;  2EV5 A;  2F5F A;  2DTR A;  3JAM R;  1DDN A;  2F5E A;  2QQ9 A;  1ON1 A;  4O5V A;  2QQA A;  2QQB A;  1BI2 A;  2TDX A;  2EV0 A;  4HX7 A;  1BI0 A;  5IT9 R;  1G3S A;  3GLX A;  5A2Q R;  3R61 A;  2H09 A;  1G3Y A;  4HV5 A;  4HV6 A;  2F5D A;  1BI1 A;  4HX4 A;  2P0T A; 
#chains in the Genus database with same CATH homology
 3J80 R;  1RQ6 A;  3JAM R;  5FLX R;  5IT9 R;  5A2Q R;  3J7A W;  3J81 R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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