3MGZA

Crystal structure of dhbps domain of bi-functional dhbps/gtp cyclohydrolase ii from mycobacterium tuberculosis at ph 4.0
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
206
structure length
186
Chain Sequence
MTRLDSVERAVADIAAGKAVIVIDDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSMAHTDELRVFADEHGLALITIADLIEWRRKHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
publication title Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 60
structure length 186
sequence length 206
ec nomenclature ec 3.5.4.25: GTP cyclohydrolase II.
pdb deposition date 2010-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 3mgzA00
1KK9A 1SNNA 1PVWA 4P8EA 4P8JA 4P6CA 1TKUA 4P6PA 3L7VA 3LRJA 3MK5A 4P6DA 4I14A 2EQAA 1HRUA 1IEZA 1K4OA 1K7JA 3LQUA 3AJEA 1G57A 1K4IA 2RIUA 3H07A 4P77A 1K4LA 1TKSA 4FFJA 3MGZA 1JCUA 1PVYA 1K49A 4E1BA 2MX1A 1G58A 3MIOA 1K4PA 3LS6A 2RISA
chains in the Genus database with same CATH superfamily
1KK9A 1SNNA 1PVWA 4P8EA 4P8JA 4P6CA 1TKUA 3VF2A 3VTIA 4P6PA 3VEOA 3L7VA 3VEWA 3LRJA 3VENA 3MK5A 4P6DA 4I14A 3TSUA 2EQAA 3VEXA 1HRUA 3TSPA 1IEZA 3VESA 3VEZA 1K4OA 1K7JA 3LQUA 3AJEA 3TTDA 1G57A 3VF4A 1K4IA 2RIUA 3H07A 4P77A 1K4LA 3VETA 1TKSA 4FFJA 3MGZA 1JCUA 1PVYA 1K49A 3TTFA 4E1BA 2MX1A 3TTCA 3TSQA 3VTHA 1G58A 3MIOA 3VERA 1K4PA 3LS6A 2RISA
chains in the Genus database with same CATH topology
1KK9A 1SNNA 1PVWA 4P8EA 4P8JA 4P6CA 1TKUA 3VF2A 3VTIA 4P6PA 3VEOA 3L7VA 3VEWA 3LRJA 3VENA 3MK5A 4P6DA 4I14A 3TSUA 2EQAA 3VEXA 1HRUA 3TSPA 1IEZA 3VESA 3VEZA 1K4OA 1K7JA 3LQUA 3AJEA 3TTDA 1G57A 3VF4A 1K4IA 2RIUA 3H07A 4P77A 1K4LA 3VETA 1TKSA 4FFJA 3MGZA 1JCUA 1PVYA 1K49A 3TTFA 4E1BA 2MX1A 3TTCA 3TSQA 3VTHA 1G58A 3MIOA 3VERA 1K4PA 3LS6A 2RISA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KK9 A;  1SNN A;  1PVW A;  4P8E A;  4P8J A;  4P6C A;  1TKU A;  4P6P A;  3L7V A;  3LRJ A;  3MK5 A;  4P6D A;  4I14 A;  2EQA A;  1HRU A;  1IEZ A;  1K4O A;  1K7J A;  3LQU A;  3AJE A;  1G57 A;  1K4I A;  2RIU A;  3H07 A;  4P77 A;  1K4L A;  1TKS A;  4FFJ A;  3MGZ A;  1JCU A;  1PVY A;  1K49 A;  4E1B A;  2MX1 A;  1G58 A;  3MIO A;  1K4P A;  3LS6 A;  2RIS A; 
#chains in the Genus database with same CATH topology
 1KK9 A;  1SNN A;  1PVW A;  4P8E A;  4P8J A;  4P6C A;  1TKU A;  3VF2 A;  3VTI A;  4P6P A;  3VEO A;  3L7V A;  3VEW A;  3LRJ A;  3VEN A;  3MK5 A;  4P6D A;  4I14 A;  3TSU A;  2EQA A;  3VEX A;  1HRU A;  3TSP A;  1IEZ A;  3VES A;  3VEZ A;  1K4O A;  1K7J A;  3LQU A;  3AJE A;  3TTD A;  1G57 A;  3VF4 A;  1K4I A;  2RIU A;  3H07 A;  4P77 A;  1K4L A;  3VET A;  1TKS A;  4FFJ A;  3MGZ A;  1JCU A;  1PVY A;  1K49 A;  3TTF A;  4E1B A;  2MX1 A;  3TTC A;  3TSQ A;  3VTH A;  1G58 A;  3MIO A;  3VER A;  1K4P A;  3LS6 A;  2RIS A; 
#chains in the Genus database with same CATH homology
 1KK9 A;  1SNN A;  1PVW A;  4P8E A;  4P8J A;  4P6C A;  1TKU A;  3VF2 A;  3VTI A;  4P6P A;  3VEO A;  3L7V A;  3VEW A;  3LRJ A;  3VEN A;  3MK5 A;  4P6D A;  4I14 A;  3TSU A;  2EQA A;  3VEX A;  1HRU A;  3TSP A;  1IEZ A;  3VES A;  3VEZ A;  1K4O A;  1K7J A;  3LQU A;  3AJE A;  3TTD A;  1G57 A;  3VF4 A;  1K4I A;  2RIU A;  3H07 A;  4P77 A;  1K4L A;  3VET A;  1TKS A;  4FFJ A;  3MGZ A;  1JCU A;  1PVY A;  1K49 A;  3TTF A;  4E1B A;  2MX1 A;  3TTC A;  3TSQ A;  3VTH A;  1G58 A;  3MIO A;  3VER A;  1K4P A;  3LS6 A;  2RIS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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