3K7VC

Protein phosphatase 2a core complex bound to dinophysistoxin-1
Total Genus 107
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
288
structure length
288
Chain Sequence
FTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Signaling protein/hydrolase
molecule keywords Serine/threonine-protein phosphatase 2A 65 kDa regulatory su
publication title A structural basis for the reduced toxicity of dinophysistoxin-2.
pubmed doi rcsb
source organism Homo sapiens
total genus 107
structure length 288
sequence length 288
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3k7vC00
3IB7A 2HYPA 2Z06A 3THNA 1S3LA 4M0VA 3RL3A 5JPEA 4TUIA 4LU9A 1Z2XA 1WARA 1JK7A 4WWLA 1QFCA 1TCOA 4Q7FA 2A22A 3PSOA 4V0VA 4J6OA 3H69A 4MP0A 1HP1A 4FBQA 4G9JA 2R17A 2NYMC 1QHWA 1G5BA 4H2FA 4UT3A 3IVEA 3QFMA 3AUZA 3H63A 4OR9A 1S95A 4UT3B 3K7WC 4UWQA 3H62B 5DNYA 3TGHA 3AV0A 3DSCA 4O5GA 3N5UA 3H60A 2HYOA 1M63A 4H2BA 4KKZA 3QFOA 3GVEA 4DT2A 3DW8C 4MOVA 4MOYA 3K7VC 4O4KA 4V0XA 4V0WA 3E7AA 4H2GA 2QJCA 3EGHA 1XM7A 3H68A 1IT6A 5B8IA 1WAO1 4DHLA 1S70A 3FGAC 2AHDA 3H61A 4ORAA 4ZX2A 3E7BA 2GJUA 3QG5C 5C1VA 2IE3C 2WDEA 3H67A 4TUGA 2IE4C 4HD0A 1HO5A 4O43A 4O24A 5JJTA 4H1YP 1HPUA 2BDXA 3JYFA 2NYLC 1W24A 2P6BA 4I5NC 4ZVZA 3V4YA 1Z2WA 1UF3A 4F0ZA 2HY1A 1OI8A 1S8EA 2WDDA 4I5LC 2Q8UA 1AUIA 2QFRA 2WDFA 3KBPA 3ICFA 2ZBMA 2O8GA 3C9FA 4ORBA 1T71A 1U32A 1UTEA 3QFKA 4NZVA 5HPEA 4FCXA 2XMOA 4H1SA 5GTUA 5J28A 3P71C 1II7A 4YKEA 3RL5A 2BCDA 4LTYA 2USHA 4H2IA 5JPFA 1FJMA 2DFJA 1S3NA 3QFNA 3T1IA 2IAEC 2BQ8X 5INBA 3ZTVA 1NNWA 2CV9A 4UT2A 3ZU0A 1USHA 3CK2A 1XZWA 4FBWA 4XPNA 3H64A 3EGGA 2Z72A 2NXFA 3LL8A 4KBPA 2QFPA 5IOHA 4IYPC 1S3MA 4IL1A 2WDCA 3IVDA 4ORCA 1KBPA 1T70A 5EQVA 1MF8A 3RL4A 3THOB 4DSYA 2KKNA 1SU1A 4JA9A 4JA7A 4B2OA 2JOGA 2NPPC 1OIDA 2YVTA 3PSNA 3IB8A 3DSDA 3RQZA 3H66A 4LACC 1OIEA 2Z1AA 3HVQA 4FBKA 1V73A 3C5WC 2O8AA 5F3WA
chains in the Genus database with same CATH superfamily
3IB7A 2HYPA 2Z06A 3THNA 1S3LA 4M0VA 3RL3A 5JPEA 4TUIA 4LU9A 1Z2XA 1WARA 1JK7A 2DXLA 1QFCA 1TCOA 4WWLA 4Q7FA 2A22A 3PSOA 4V0VA 4J6OA 3H69A 4MP0A 1HP1A 4FBQA 4G9JA 2R17A 2NYMC 1QHWA 1G5BA 4H2FA 4UT3A 3IVEA 3QFMA 3AUZA 3H63A 4OR9A 1S95A 4UT3B 3K7WC 4UWQA 3H62B 5DNYA 3TGHA 3FLOA 3AV0A 3DSCA 4O5GA 3N5UA 3H60A 2HYOA 1M63A 4H2BA 4KKZA 3QFOA 3E0JA 3GVEA 4DT2A 3DW8C 4MOVA 4MOYA 3K7VC 4O4KA 4V0XA 4V0WA 3E7AA 4H2GA 2QJCA 3EGHA 1XM7A 3H68A 1IT6A 5B8IA 1WAO1 4DHLA 1S70A 3FGAC 2AHDA 3H61A 4ORAA 4ZX2A 3E7BA 2GJUA 3QG5C 5C1VA 2IE3C 2WDEA 3H67A 4TUGA 2IE4C 4HD0A 1HO5A 4O43A 4O24A 5JJTA 4H1YP 1HPUA 2BDXA 3JYFA 2NYLC 1W24A 2P6BA 4I5NC 4ZVZA 3V4YA 1Z2WA 1UF3A 4F0ZA 2HY1A 1OI8A 1S8EA 2WDDA 4I5LC 2Q8UA 1AUIA 2QFRA 2WDFA 3KBPA 3ICFA 2ZBMA 2O8GA 3C9FA 4ORBA 1T71A 1U32A 1UTEA 2ZO9B 3QFKA 4NZVA 5HPEA 4FCXA 2XMOA 4H1SA 5GTUA 5J28A 3P71C 1II7A 4YKEA 3RL5A 2BCDA 4LTYA 2USHA 4H2IA 5JPFA 1FJMA 2ZOAA 2DFJA 1S3NA 3QFNA 3T1IA 2IAEC 2BQ8X 5INBA 3ZTVA 1NNWA 2CV9A 4UT2A 3ZU0A 1USHA 3CK2A 1XZWA 4FBWA 4XPNA 3H64A 3EGGA 2Z72A 2NXFA 3LL8A 4KBPA 2QFPA 5IOHA 4IYPC 2DXNA 1S3MA 3D03A 4IL1A 2WDCA 3IVDA 4ORCA 1KBPA 1T70A 5EQVA 1MF8A 3RL4A 3THOB 4DSYA 2KKNA 1SU1A 4JA9A 4JA7A 4B2OA 2JOGA 2NPPC 1OIDA 2YVTA 3PSNA 2YEQA 3IB8A 3DSDA 3RQZA 3H66A 4LACC 1OIEA 2Z1AA 3HVQA 4FBKA 1V73A 3C5WC 2O8AA 5F3WA
chains in the Genus database with same CATH topology
3IB7A 2HYPA 2Z06A 3THNA 1S3LA 4M0VA 3RL3A 5JPEA 4TUIA 4LU9A 1Z2XA 1WARA 1JK7A 2DXLA 1QFCA 1TCOA 4WWLA 4Q7FA 2A22A 3PSOA 4V0VA 4J6OA 3H69A 4MP0A 1HP1A 4FBQA 4G9JA 2R17A 2NYMC 1QHWA 1G5BA 4H2FA 4UT3A 3IVEA 3QFMA 3AUZA 3H63A 4OR9A 1S95A 4UT3B 3K7WC 4UWQA 3H62B 5DNYA 3TGHA 3FLOA 3AV0A 3DSCA 4O5GA 3N5UA 3H60A 2HYOA 1M63A 4H2BA 4KKZA 3QFOA 3E0JA 3GVEA 4DT2A 3DW8C 4MOVA 4MOYA 3K7VC 4O4KA 4V0XA 4V0WA 3E7AA 4H2GA 2QJCA 3EGHA 1XM7A 3H68A 1IT6A 5B8IA 1WAO1 4DHLA 1S70A 3FGAC 2AHDA 3H61A 4ORAA 4ZX2A 3E7BA 2GJUA 3QG5C 5C1VA 2IE3C 2WDEA 3H67A 4TUGA 2IE4C 4HD0A 1HO5A 4O43A 4O24A 5JJTA 4H1YP 1HPUA 2BDXA 3JYFA 2NYLC 1W24A 2P6BA 4I5NC 4ZVZA 3V4YA 1Z2WA 1UF3A 4F0ZA 2HY1A 1OI8A 1S8EA 2WDDA 4I5LC 2Q8UA 1AUIA 2QFRA 2WDFA 3KBPA 3ICFA 2ZBMA 2O8GA 3C9FA 4ORBA 1T71A 1U32A 1UTEA 2ZO9B 3QFKA 4NZVA 5HPEA 4FCXA 2XMOA 4H1SA 5GTUA 5J28A 3P71C 1II7A 4YKEA 3RL5A 2BCDA 4LTYA 2USHA 4H2IA 5JPFA 1FJMA 2ZOAA 2DFJA 1S3NA 3QFNA 3T1IA 2IAEC 2BQ8X 5INBA 3ZTVA 1NNWA 2CV9A 4UT2A 3ZU0A 1USHA 3CK2A 1XZWA 4FBWA 4XPNA 3H64A 3EGGA 2Z72A 2NXFA 3LL8A 4KBPA 2QFPA 5IOHA 4IYPC 2DXNA 1S3MA 3D03A 4IL1A 2WDCA 3IVDA 4ORCA 1KBPA 1T70A 5EQVA 1MF8A 3RL4A 3THOB 4DSYA 2KKNA 1SU1A 4JA9A 4JA7A 4B2OA 2JOGA 2NPPC 1OIDA 2YVTA 3PSNA 2YEQA 3IB8A 3DSDA 3RQZA 3H66A 4LACC 1OIEA 2Z1AA 3HVQA 4FBKA 1V73A 3C5WC 2O8AA 5F3WA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3IB7 A;  2HYP A;  2Z06 A;  3THN A;  1S3L A;  4M0V A;  3RL3 A;  5JPE A;  4TUI A;  4LU9 A;  1Z2X A;  1WAR A;  1JK7 A;  4WWL A;  1QFC A;  1TCO A;  4Q7F A;  2A22 A;  3PSO A;  4V0V A;  4J6O A;  3H69 A;  4MP0 A;  1HP1 A;  4FBQ A;  4G9J A;  2R17 A;  2NYM C;  1QHW A;  1G5B A;  4H2F A;  4UT3 A;  3IVE A;  3QFM A;  3AUZ A;  3H63 A;  4OR9 A;  1S95 A;  4UT3 B;  3K7W C;  4UWQ A;  3H62 B;  5DNY A;  3TGH A;  3AV0 A;  3DSC A;  4O5G A;  3N5U A;  3H60 A;  2HYO A;  1M63 A;  4H2B A;  4KKZ A;  3QFO A;  3GVE A;  4DT2 A;  3DW8 C;  4MOV A;  4MOY A;  3K7V C;  4O4K A;  4V0X A;  4V0W A;  3E7A A;  4H2G A;  2QJC A;  3EGH A;  1XM7 A;  3H68 A;  1IT6 A;  5B8I A;  1WAO 1;  4DHL A;  1S70 A;  3FGA C;  2AHD A;  3H61 A;  4ORA A;  4ZX2 A;  3E7B A;  2GJU A;  3QG5 C;  5C1V A;  2IE3 C;  2WDE A;  3H67 A;  4TUG A;  2IE4 C;  4HD0 A;  1HO5 A;  4O43 A;  4O24 A;  5JJT A;  4H1Y P;  1HPU A;  2BDX A;  3JYF A;  2NYL C;  1W24 A;  2P6B A;  4I5N C;  4ZVZ A;  3V4Y A;  1Z2W A;  1UF3 A;  4F0Z A;  2HY1 A;  1OI8 A;  1S8E A;  2WDD A;  4I5L C;  2Q8U A;  1AUI A;  2QFR A;  2WDF A;  3KBP A;  3ICF A;  2ZBM A;  2O8G A;  3C9F A;  4ORB A;  1T71 A;  1U32 A;  1UTE A;  3QFK A;  4NZV A;  5HPE A;  4FCX A;  2XMO A;  4H1S A;  5GTU A;  5J28 A;  3P71 C;  1II7 A;  4YKE A;  3RL5 A;  2BCD A;  4LTY A;  2USH A;  4H2I A;  5JPF A;  1FJM A;  2DFJ A;  1S3N A;  3QFN A;  3T1I A;  2IAE C;  2BQ8 X;  5INB A;  3ZTV A;  1NNW A;  2CV9 A;  4UT2 A;  3ZU0 A;  1USH A;  3CK2 A;  1XZW A;  4FBW A;  4XPN A;  3H64 A;  3EGG A;  2Z72 A;  2NXF A;  3LL8 A;  4KBP A;  2QFP A;  5IOH A;  4IYP C;  1S3M A;  4IL1 A;  2WDC A;  3IVD A;  4ORC A;  1KBP A;  1T70 A;  5EQV A;  1MF8 A;  3RL4 A;  3THO B;  4DSY A;  2KKN A;  1SU1 A;  4JA9 A;  4JA7 A;  4B2O A;  2JOG A;  2NPP C;  1OID A;  2YVT A;  3PSN A;  3IB8 A;  3DSD A;  3RQZ A;  3H66 A;  4LAC C;  1OIE A;  2Z1A A;  3HVQ A;  4FBK A;  1V73 A;  3C5W C;  2O8A A;  5F3W A; 
#chains in the Genus database with same CATH topology
 3IB7 A;  2HYP A;  2Z06 A;  3THN A;  1S3L A;  4M0V A;  3RL3 A;  5JPE A;  4TUI A;  4LU9 A;  1Z2X A;  1WAR A;  1JK7 A;  2DXL A;  1QFC A;  1TCO A;  4WWL A;  4Q7F A;  2A22 A;  3PSO A;  4V0V A;  4J6O A;  3H69 A;  4MP0 A;  1HP1 A;  4FBQ A;  4G9J A;  2R17 A;  2NYM C;  1QHW A;  1G5B A;  4H2F A;  4UT3 A;  3IVE A;  3QFM A;  3AUZ A;  3H63 A;  4OR9 A;  1S95 A;  4UT3 B;  3K7W C;  4UWQ A;  3H62 B;  5DNY A;  3TGH A;  3FLO A;  3AV0 A;  3DSC A;  4O5G A;  3N5U A;  3H60 A;  2HYO A;  1M63 A;  4H2B A;  4KKZ A;  3QFO A;  3E0J A;  3GVE A;  4DT2 A;  3DW8 C;  4MOV A;  4MOY A;  3K7V C;  4O4K A;  4V0X A;  4V0W A;  3E7A A;  4H2G A;  2QJC A;  3EGH A;  1XM7 A;  3H68 A;  1IT6 A;  5B8I A;  1WAO 1;  4DHL A;  1S70 A;  3FGA C;  2AHD A;  3H61 A;  4ORA A;  4ZX2 A;  3E7B A;  2GJU A;  3QG5 C;  5C1V A;  2IE3 C;  2WDE A;  3H67 A;  4TUG A;  2IE4 C;  4HD0 A;  1HO5 A;  4O43 A;  4O24 A;  5JJT A;  4H1Y P;  1HPU A;  2BDX A;  3JYF A;  2NYL C;  1W24 A;  2P6B A;  4I5N C;  4ZVZ A;  3V4Y A;  1Z2W A;  1UF3 A;  4F0Z A;  2HY1 A;  1OI8 A;  1S8E A;  2WDD A;  4I5L C;  2Q8U A;  1AUI A;  2QFR A;  2WDF A;  3KBP A;  3ICF A;  2ZBM A;  2O8G A;  3C9F A;  4ORB A;  1T71 A;  1U32 A;  1UTE A;  2ZO9 B;  3QFK A;  4NZV A;  5HPE A;  4FCX A;  2XMO A;  4H1S A;  5GTU A;  5J28 A;  3P71 C;  1II7 A;  4YKE A;  3RL5 A;  2BCD A;  4LTY A;  2USH A;  4H2I A;  5JPF A;  1FJM A;  2ZOA A;  2DFJ A;  1S3N A;  3QFN A;  3T1I A;  2IAE C;  2BQ8 X;  5INB A;  3ZTV A;  1NNW A;  2CV9 A;  4UT2 A;  3ZU0 A;  1USH A;  3CK2 A;  1XZW A;  4FBW A;  4XPN A;  3H64 A;  3EGG A;  2Z72 A;  2NXF A;  3LL8 A;  4KBP A;  2QFP A;  5IOH A;  4IYP C;  2DXN A;  1S3M A;  3D03 A;  4IL1 A;  2WDC A;  3IVD A;  4ORC A;  1KBP A;  1T70 A;  5EQV A;  1MF8 A;  3RL4 A;  3THO B;  4DSY A;  2KKN A;  1SU1 A;  4JA9 A;  4JA7 A;  4B2O A;  2JOG A;  2NPP C;  1OID A;  2YVT A;  3PSN A;  2YEQ A;  3IB8 A;  3DSD A;  3RQZ A;  3H66 A;  4LAC C;  1OIE A;  2Z1A A;  3HVQ A;  4FBK A;  1V73 A;  3C5W C;  2O8A A;  5F3W A; 
#chains in the Genus database with same CATH homology
 3IB7 A;  2HYP A;  2Z06 A;  3THN A;  1S3L A;  4M0V A;  3RL3 A;  5JPE A;  4TUI A;  4LU9 A;  1Z2X A;  1WAR A;  1JK7 A;  2DXL A;  1QFC A;  1TCO A;  4WWL A;  4Q7F A;  2A22 A;  3PSO A;  4V0V A;  4J6O A;  3H69 A;  4MP0 A;  1HP1 A;  4FBQ A;  4G9J A;  2R17 A;  2NYM C;  1QHW A;  1G5B A;  4H2F A;  4UT3 A;  3IVE A;  3QFM A;  3AUZ A;  3H63 A;  4OR9 A;  1S95 A;  4UT3 B;  3K7W C;  4UWQ A;  3H62 B;  5DNY A;  3TGH A;  3FLO A;  3AV0 A;  3DSC A;  4O5G A;  3N5U A;  3H60 A;  2HYO A;  1M63 A;  4H2B A;  4KKZ A;  3QFO A;  3E0J A;  3GVE A;  4DT2 A;  3DW8 C;  4MOV A;  4MOY A;  3K7V C;  4O4K A;  4V0X A;  4V0W A;  3E7A A;  4H2G A;  2QJC A;  3EGH A;  1XM7 A;  3H68 A;  1IT6 A;  5B8I A;  1WAO 1;  4DHL A;  1S70 A;  3FGA C;  2AHD A;  3H61 A;  4ORA A;  4ZX2 A;  3E7B A;  2GJU A;  3QG5 C;  5C1V A;  2IE3 C;  2WDE A;  3H67 A;  4TUG A;  2IE4 C;  4HD0 A;  1HO5 A;  4O43 A;  4O24 A;  5JJT A;  4H1Y P;  1HPU A;  2BDX A;  3JYF A;  2NYL C;  1W24 A;  2P6B A;  4I5N C;  4ZVZ A;  3V4Y A;  1Z2W A;  1UF3 A;  4F0Z A;  2HY1 A;  1OI8 A;  1S8E A;  2WDD A;  4I5L C;  2Q8U A;  1AUI A;  2QFR A;  2WDF A;  3KBP A;  3ICF A;  2ZBM A;  2O8G A;  3C9F A;  4ORB A;  1T71 A;  1U32 A;  1UTE A;  2ZO9 B;  3QFK A;  4NZV A;  5HPE A;  4FCX A;  2XMO A;  4H1S A;  5GTU A;  5J28 A;  3P71 C;  1II7 A;  4YKE A;  3RL5 A;  2BCD A;  4LTY A;  2USH A;  4H2I A;  5JPF A;  1FJM A;  2ZOA A;  2DFJ A;  1S3N A;  3QFN A;  3T1I A;  2IAE C;  2BQ8 X;  5INB A;  3ZTV A;  1NNW A;  2CV9 A;  4UT2 A;  3ZU0 A;  1USH A;  3CK2 A;  1XZW A;  4FBW A;  4XPN A;  3H64 A;  3EGG A;  2Z72 A;  2NXF A;  3LL8 A;  4KBP A;  2QFP A;  5IOH A;  4IYP C;  2DXN A;  1S3M A;  3D03 A;  4IL1 A;  2WDC A;  3IVD A;  4ORC A;  1KBP A;  1T70 A;  5EQV A;  1MF8 A;  3RL4 A;  3THO B;  4DSY A;  2KKN A;  1SU1 A;  4JA9 A;  4JA7 A;  4B2O A;  2JOG A;  2NPP C;  1OID A;  2YVT A;  3PSN A;  2YEQ A;  3IB8 A;  3DSD A;  3RQZ A;  3H66 A;  4LAC C;  1OIE A;  2Z1A A;  3HVQ A;  4FBK A;  1V73 A;  3C5W C;  2O8A A;  5F3W A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite