3RL3A

Rat metallophosphodiesterase mpped2
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
276
Chain Sequence
VTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Metallophosphoesterase MPPED2
publication title Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 86
structure length 276
sequence length 281
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3rl3A00
1W24A 5JJTA 3QFKA 3K7VC 2ZBMA 3KBPA 4ZX2A 3DSCA 2QJCA 3ZTVA 4LACC 2HY1A 3H60A 4FBWA 3C9FA 4DSYA 3H69A 3EGGA 4M0VA 1V73A 4XPNA 4DT2A 1MF8A 4MP0A 3RL4A 2O8GA 4I5LC 2O8AA 4HD0A 4H1SA 3H62B 1HPUA 5INBA 2P6BA 2BDXA 1Z2XA 1OIDA 3H63A 3TGHA 3EGHA 2A22A 3JYFA 4IL1A 2IAEC 3E7BA 4O24A 2DFJA 4G9JA 4Q7FA 1AUIA 3H67A 3DW8C 3IB7A 5DNYA 4V0VA 4FBKA 4OR9A 3RL3A 3LL8A 3AUZA 1OIEA 4MOYA 4UT2A 3T1IA 4LU9A 2YVTA 4O43A 4DHLA 4ORBA 2IE4C 1S3NA 3H68A 3H61A 2AHDA 2WDEA 3N5UA 3QG5C 5JPEA 2Z06A 3DSDA 4H2FA 3E7AA 2HYOA 3K7WC 3RQZA 3THNA 4ORAA 2NXFA 2CV9A 4H2GA 3P71C 3V4YA 3HVQA 4KKZA 2QFRA 2BQ8X 1S70A 4KBPA 3PSOA 1WAO1 1WARA 3ZU0A 1FJMA 3GVEA 2NYMC 5F3WA 1JK7A 3PSNA 3QFMA 4JA9A 2NPPC 3C5WC 3QFOA 2JOGA 2Z72A 2KKNA 1G5BA 1USHA 3QFNA 5EQVA 4NZVA 1UTEA 4WWLA 1S95A 4H2BA 3RL5A 4YKEA 2BCDA 5C1VA 3AV0A 4TUGA 1U32A 2WDDA 5HPEA 1Z2WA 1KBPA 4F0ZA 3THOB 1XM7A 4H1YP 1HO5A 2NYLC 4TUIA 4UT3B 5IOHA 2HYPA 4V0WA 2IE3C 2QFPA 1M63A 1T71A 4LTYA 3H66A 1T70A 1S3MA 2Z1AA 1S8EA 3IVDA 1II7A 1SU1A 1S3LA 2USHA 3CK2A 4IYPC 3IB8A 5JPFA 4H2IA 4O5GA 2GJUA 4O4KA 3H64A 4I5NC 4UWQA 2XMOA 2R17A 4FCXA 1QHWA 4ZVZA 1XZWA 4JA7A 2WDCA 5J28A 1TCOA 3IVEA 5B8IA 5GTUA 4V0XA 1IT6A 3ICFA 2Q8UA 1UF3A 1QFCA 4UT3A 4MOVA 1NNWA 4FBQA 4J6OA 1OI8A 2WDFA 4ORCA 3FGAC 4B2OA 1HP1A
chains in the Genus database with same CATH superfamily
1W24A 5JJTA 3QFKA 3K7VC 2ZBMA 3KBPA 4ZX2A 3DSCA 2QJCA 3ZTVA 4LACC 2HY1A 2ZO9B 3H60A 4FBWA 3C9FA 4DSYA 3H69A 3EGGA 4M0VA 1V73A 4XPNA 4DT2A 1MF8A 4MP0A 2YEQA 3RL4A 2O8GA 4I5LC 2O8AA 4HD0A 4H1SA 3H62B 1HPUA 2DXNA 5INBA 2P6BA 2BDXA 2DXLA 1Z2XA 1OIDA 3H63A 3TGHA 3EGHA 2A22A 3JYFA 4IL1A 2IAEC 3E7BA 4O24A 2DFJA 4G9JA 4Q7FA 1AUIA 3H67A 3DW8C 3IB7A 5DNYA 4V0VA 4FBKA 4OR9A 3RL3A 3LL8A 3AUZA 1OIEA 4MOYA 4UT2A 3T1IA 4LU9A 2YVTA 4O43A 4DHLA 4ORBA 2IE4C 1S3NA 3H68A 3H61A 2AHDA 2WDEA 3N5UA 3QG5C 5JPEA 2Z06A 3DSDA 4H2FA 3E7AA 2HYOA 3K7WC 3RQZA 3THNA 4ORAA 2NXFA 2CV9A 4H2GA 3P71C 3V4YA 3HVQA 4KKZA 2QFRA 2BQ8X 1S70A 4KBPA 3PSOA 1WAO1 1WARA 3ZU0A 1FJMA 3GVEA 2NYMC 5F3WA 1JK7A 3PSNA 3QFMA 4JA9A 2NPPC 3C5WC 3QFOA 2JOGA 2Z72A 2KKNA 1G5BA 1USHA 3QFNA 3E0JA 5EQVA 4NZVA 1UTEA 4WWLA 1S95A 4H2BA 3RL5A 4YKEA 2BCDA 5C1VA 3AV0A 4TUGA 1U32A 2WDDA 5HPEA 1Z2WA 1KBPA 4F0ZA 3THOB 1XM7A 4H1YP 1HO5A 2NYLC 4TUIA 4UT3B 5IOHA 2HYPA 4V0WA 2IE3C 2QFPA 1M63A 1T71A 4LTYA 3H66A 1T70A 1S3MA 1S8EA 2Z1AA 3FLOA 3IVDA 1II7A 1SU1A 1S3LA 2USHA 3CK2A 4IYPC 3IB8A 5JPFA 4H2IA 4O5GA 2GJUA 4O4KA 3H64A 4I5NC 4UWQA 2XMOA 2R17A 4FCXA 1QHWA 4ZVZA 1XZWA 4JA7A 2WDCA 5J28A 1TCOA 3IVEA 5B8IA 5GTUA 3D03A 4V0XA 1IT6A 3ICFA 2Q8UA 1UF3A 1QFCA 4UT3A 4MOVA 1NNWA 2ZOAA 4FBQA 4J6OA 1OI8A 2WDFA 4ORCA 3FGAC 4B2OA 1HP1A
chains in the Genus database with same CATH topology
1W24A 5JJTA 3QFKA 3K7VC 2ZBMA 3KBPA 4ZX2A 3DSCA 2QJCA 3ZTVA 4LACC 2HY1A 2ZO9B 3H60A 4FBWA 3C9FA 4DSYA 3H69A 3EGGA 4M0VA 1V73A 4XPNA 4DT2A 1MF8A 4MP0A 2YEQA 3RL4A 2O8GA 4I5LC 2O8AA 4HD0A 4H1SA 3H62B 1HPUA 2DXNA 5INBA 2P6BA 2BDXA 2DXLA 1Z2XA 1OIDA 3H63A 3TGHA 3EGHA 2A22A 3JYFA 4IL1A 2IAEC 3E7BA 4O24A 2DFJA 4G9JA 4Q7FA 1AUIA 3H67A 3DW8C 3IB7A 5DNYA 4V0VA 4FBKA 4OR9A 3RL3A 3LL8A 3AUZA 1OIEA 4MOYA 4UT2A 3T1IA 4LU9A 2YVTA 4O43A 4DHLA 4ORBA 2IE4C 1S3NA 3H68A 3H61A 2AHDA 2WDEA 3N5UA 3QG5C 5JPEA 2Z06A 3DSDA 4H2FA 3E7AA 2HYOA 3K7WC 3RQZA 3THNA 4ORAA 2NXFA 2CV9A 4H2GA 3P71C 3V4YA 3HVQA 4KKZA 2QFRA 2BQ8X 1S70A 4KBPA 3PSOA 1WAO1 1WARA 3ZU0A 1FJMA 3GVEA 2NYMC 5F3WA 1JK7A 3PSNA 3QFMA 4JA9A 2NPPC 3C5WC 3QFOA 2JOGA 2Z72A 2KKNA 1G5BA 1USHA 3QFNA 3E0JA 5EQVA 4NZVA 1UTEA 4WWLA 1S95A 4H2BA 3RL5A 4YKEA 2BCDA 5C1VA 3AV0A 4TUGA 1U32A 2WDDA 5HPEA 1Z2WA 1KBPA 4F0ZA 3THOB 1XM7A 4H1YP 1HO5A 2NYLC 4TUIA 4UT3B 5IOHA 2HYPA 4V0WA 2IE3C 2QFPA 1M63A 1T71A 4LTYA 3H66A 1T70A 1S3MA 1S8EA 2Z1AA 3FLOA 3IVDA 1II7A 1SU1A 1S3LA 2USHA 3CK2A 4IYPC 3IB8A 5JPFA 4H2IA 4O5GA 2GJUA 4O4KA 3H64A 4I5NC 4UWQA 2XMOA 2R17A 4FCXA 1QHWA 4ZVZA 1XZWA 4JA7A 2WDCA 5J28A 1TCOA 3IVEA 5B8IA 5GTUA 3D03A 4V0XA 1IT6A 3ICFA 2Q8UA 1UF3A 1QFCA 4UT3A 4MOVA 1NNWA 2ZOAA 4FBQA 4J6OA 1OI8A 2WDFA 4ORCA 3FGAC 4B2OA 1HP1A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1W24 A;  5JJT A;  3QFK A;  3K7V C;  2ZBM A;  3KBP A;  4ZX2 A;  3DSC A;  2QJC A;  3ZTV A;  4LAC C;  2HY1 A;  3H60 A;  4FBW A;  3C9F A;  4DSY A;  3H69 A;  3EGG A;  4M0V A;  1V73 A;  4XPN A;  4DT2 A;  1MF8 A;  4MP0 A;  3RL4 A;  2O8G A;  4I5L C;  2O8A A;  4HD0 A;  4H1S A;  3H62 B;  1HPU A;  5INB A;  2P6B A;  2BDX A;  1Z2X A;  1OID A;  3H63 A;  3TGH A;  3EGH A;  2A22 A;  3JYF A;  4IL1 A;  2IAE C;  3E7B A;  4O24 A;  2DFJ A;  4G9J A;  4Q7F A;  1AUI A;  3H67 A;  3DW8 C;  3IB7 A;  5DNY A;  4V0V A;  4FBK A;  4OR9 A;  3RL3 A;  3LL8 A;  3AUZ A;  1OIE A;  4MOY A;  4UT2 A;  3T1I A;  4LU9 A;  2YVT A;  4O43 A;  4DHL A;  4ORB A;  2IE4 C;  1S3N A;  3H68 A;  3H61 A;  2AHD A;  2WDE A;  3N5U A;  3QG5 C;  5JPE A;  2Z06 A;  3DSD A;  4H2F A;  3E7A A;  2HYO A;  3K7W C;  3RQZ A;  3THN A;  4ORA A;  2NXF A;  2CV9 A;  4H2G A;  3P71 C;  3V4Y A;  3HVQ A;  4KKZ A;  2QFR A;  2BQ8 X;  1S70 A;  4KBP A;  3PSO A;  1WAO 1;  1WAR A;  3ZU0 A;  1FJM A;  3GVE A;  2NYM C;  5F3W A;  1JK7 A;  3PSN A;  3QFM A;  4JA9 A;  2NPP C;  3C5W C;  3QFO A;  2JOG A;  2Z72 A;  2KKN A;  1G5B A;  1USH A;  3QFN A;  5EQV A;  4NZV A;  1UTE A;  4WWL A;  1S95 A;  4H2B A;  3RL5 A;  4YKE A;  2BCD A;  5C1V A;  3AV0 A;  4TUG A;  1U32 A;  2WDD A;  5HPE A;  1Z2W A;  1KBP A;  4F0Z A;  3THO B;  1XM7 A;  4H1Y P;  1HO5 A;  2NYL C;  4TUI A;  4UT3 B;  5IOH A;  2HYP A;  4V0W A;  2IE3 C;  2QFP A;  1M63 A;  1T71 A;  4LTY A;  3H66 A;  1T70 A;  1S3M A;  2Z1A A;  1S8E A;  3IVD A;  1II7 A;  1SU1 A;  1S3L A;  2USH A;  3CK2 A;  4IYP C;  3IB8 A;  5JPF A;  4H2I A;  4O5G A;  2GJU A;  4O4K A;  3H64 A;  4I5N C;  4UWQ A;  2XMO A;  2R17 A;  4FCX A;  1QHW A;  4ZVZ A;  1XZW A;  4JA7 A;  2WDC A;  5J28 A;  1TCO A;  3IVE A;  5B8I A;  5GTU A;  4V0X A;  1IT6 A;  3ICF A;  2Q8U A;  1UF3 A;  1QFC A;  4UT3 A;  4MOV A;  1NNW A;  4FBQ A;  4J6O A;  1OI8 A;  2WDF A;  4ORC A;  3FGA C;  4B2O A;  1HP1 A; 
#chains in the Genus database with same CATH topology
 1W24 A;  5JJT A;  3QFK A;  3K7V C;  2ZBM A;  3KBP A;  4ZX2 A;  3DSC A;  2QJC A;  3ZTV A;  4LAC C;  2HY1 A;  2ZO9 B;  3H60 A;  4FBW A;  3C9F A;  4DSY A;  3H69 A;  3EGG A;  4M0V A;  1V73 A;  4XPN A;  4DT2 A;  1MF8 A;  4MP0 A;  2YEQ A;  3RL4 A;  2O8G A;  4I5L C;  2O8A A;  4HD0 A;  4H1S A;  3H62 B;  1HPU A;  2DXN A;  5INB A;  2P6B A;  2BDX A;  2DXL A;  1Z2X A;  1OID A;  3H63 A;  3TGH A;  3EGH A;  2A22 A;  3JYF A;  4IL1 A;  2IAE C;  3E7B A;  4O24 A;  2DFJ A;  4G9J A;  4Q7F A;  1AUI A;  3H67 A;  3DW8 C;  3IB7 A;  5DNY A;  4V0V A;  4FBK A;  4OR9 A;  3RL3 A;  3LL8 A;  3AUZ A;  1OIE A;  4MOY A;  4UT2 A;  3T1I A;  4LU9 A;  2YVT A;  4O43 A;  4DHL A;  4ORB A;  2IE4 C;  1S3N A;  3H68 A;  3H61 A;  2AHD A;  2WDE A;  3N5U A;  3QG5 C;  5JPE A;  2Z06 A;  3DSD A;  4H2F A;  3E7A A;  2HYO A;  3K7W C;  3RQZ A;  3THN A;  4ORA A;  2NXF A;  2CV9 A;  4H2G A;  3P71 C;  3V4Y A;  3HVQ A;  4KKZ A;  2QFR A;  2BQ8 X;  1S70 A;  4KBP A;  3PSO A;  1WAO 1;  1WAR A;  3ZU0 A;  1FJM A;  3GVE A;  2NYM C;  5F3W A;  1JK7 A;  3PSN A;  3QFM A;  4JA9 A;  2NPP C;  3C5W C;  3QFO A;  2JOG A;  2Z72 A;  2KKN A;  1G5B A;  1USH A;  3QFN A;  3E0J A;  5EQV A;  4NZV A;  1UTE A;  4WWL A;  1S95 A;  4H2B A;  3RL5 A;  4YKE A;  2BCD A;  5C1V A;  3AV0 A;  4TUG A;  1U32 A;  2WDD A;  5HPE A;  1Z2W A;  1KBP A;  4F0Z A;  3THO B;  1XM7 A;  4H1Y P;  1HO5 A;  2NYL C;  4TUI A;  4UT3 B;  5IOH A;  2HYP A;  4V0W A;  2IE3 C;  2QFP A;  1M63 A;  1T71 A;  4LTY A;  3H66 A;  1T70 A;  1S3M A;  1S8E A;  2Z1A A;  3FLO A;  3IVD A;  1II7 A;  1SU1 A;  1S3L A;  2USH A;  3CK2 A;  4IYP C;  3IB8 A;  5JPF A;  4H2I A;  4O5G A;  2GJU A;  4O4K A;  3H64 A;  4I5N C;  4UWQ A;  2XMO A;  2R17 A;  4FCX A;  1QHW A;  4ZVZ A;  1XZW A;  4JA7 A;  2WDC A;  5J28 A;  1TCO A;  3IVE A;  5B8I A;  5GTU A;  3D03 A;  4V0X A;  1IT6 A;  3ICF A;  2Q8U A;  1UF3 A;  1QFC A;  4UT3 A;  4MOV A;  1NNW A;  2ZOA A;  4FBQ A;  4J6O A;  1OI8 A;  2WDF A;  4ORC A;  3FGA C;  4B2O A;  1HP1 A; 
#chains in the Genus database with same CATH homology
 1W24 A;  5JJT A;  3QFK A;  3K7V C;  2ZBM A;  3KBP A;  4ZX2 A;  3DSC A;  2QJC A;  3ZTV A;  4LAC C;  2HY1 A;  2ZO9 B;  3H60 A;  4FBW A;  3C9F A;  4DSY A;  3H69 A;  3EGG A;  4M0V A;  1V73 A;  4XPN A;  4DT2 A;  1MF8 A;  4MP0 A;  2YEQ A;  3RL4 A;  2O8G A;  4I5L C;  2O8A A;  4HD0 A;  4H1S A;  3H62 B;  1HPU A;  2DXN A;  5INB A;  2P6B A;  2BDX A;  2DXL A;  1Z2X A;  1OID A;  3H63 A;  3TGH A;  3EGH A;  2A22 A;  3JYF A;  4IL1 A;  2IAE C;  3E7B A;  4O24 A;  2DFJ A;  4G9J A;  4Q7F A;  1AUI A;  3H67 A;  3DW8 C;  3IB7 A;  5DNY A;  4V0V A;  4FBK A;  4OR9 A;  3RL3 A;  3LL8 A;  3AUZ A;  1OIE A;  4MOY A;  4UT2 A;  3T1I A;  4LU9 A;  2YVT A;  4O43 A;  4DHL A;  4ORB A;  2IE4 C;  1S3N A;  3H68 A;  3H61 A;  2AHD A;  2WDE A;  3N5U A;  3QG5 C;  5JPE A;  2Z06 A;  3DSD A;  4H2F A;  3E7A A;  2HYO A;  3K7W C;  3RQZ A;  3THN A;  4ORA A;  2NXF A;  2CV9 A;  4H2G A;  3P71 C;  3V4Y A;  3HVQ A;  4KKZ A;  2QFR A;  2BQ8 X;  1S70 A;  4KBP A;  3PSO A;  1WAO 1;  1WAR A;  3ZU0 A;  1FJM A;  3GVE A;  2NYM C;  5F3W A;  1JK7 A;  3PSN A;  3QFM A;  4JA9 A;  2NPP C;  3C5W C;  3QFO A;  2JOG A;  2Z72 A;  2KKN A;  1G5B A;  1USH A;  3QFN A;  3E0J A;  5EQV A;  4NZV A;  1UTE A;  4WWL A;  1S95 A;  4H2B A;  3RL5 A;  4YKE A;  2BCD A;  5C1V A;  3AV0 A;  4TUG A;  1U32 A;  2WDD A;  5HPE A;  1Z2W A;  1KBP A;  4F0Z A;  3THO B;  1XM7 A;  4H1Y P;  1HO5 A;  2NYL C;  4TUI A;  4UT3 B;  5IOH A;  2HYP A;  4V0W A;  2IE3 C;  2QFP A;  1M63 A;  1T71 A;  4LTY A;  3H66 A;  1T70 A;  1S3M A;  1S8E A;  2Z1A A;  3FLO A;  3IVD A;  1II7 A;  1SU1 A;  1S3L A;  2USH A;  3CK2 A;  4IYP C;  3IB8 A;  5JPF A;  4H2I A;  4O5G A;  2GJU A;  4O4K A;  3H64 A;  4I5N C;  4UWQ A;  2XMO A;  2R17 A;  4FCX A;  1QHW A;  4ZVZ A;  1XZW A;  4JA7 A;  2WDC A;  5J28 A;  1TCO A;  3IVE A;  5B8I A;  5GTU A;  3D03 A;  4V0X A;  1IT6 A;  3ICF A;  2Q8U A;  1UF3 A;  1QFC A;  4UT3 A;  4MOV A;  1NNW A;  2ZOA A;  4FBQ A;  4J6O A;  1OI8 A;  2WDF A;  4ORC A;  3FGA C;  4B2O A;  1HP1 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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