The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
135
|
sequence length |
463
|
structure length |
396
|
Chain Sequence |
EEEASVSVWDEEEDGATFTVTSRQYRPLDPLAPLPPPRSSRRLRAGTLEALVRHLLDARTAGADMMFTPALLATHRAFTSTPALFGLVADRLEALESYPPGELERTTGVAISVLSTWLASHPEDFGSEVKGQLDRLESFLLRTGYSADLIRNLRARDSPADPTDVLVFLADHLAEQLTLLDAELFLNLIPSQCLGGLWLCPSVRATVTQFNKVAGAVVSSVLGATSIGEGPREVTVRPLRPPQRARLLEKWIRVAEECRLLRNFSSVYAVVSALQSSPIHRLRAAWGETTRDSLRVFSSLCQIFSRELLTGVVPYLGTFLKDLVMLDAASKDELENGYINFDKRRKEFAILSELLRLQKECRGYDLRPNSDIQQWLQGLQPLTEAQSHRVSCEVEP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Signaling protein
|
| molecule keywords |
Ral guanine nucleotide dissociation stimulator-like 2
|
| publication title |
The guanine nucleotide exchange factor Rlf interacts with SH3 domain-containing proteins via a binding site with a preselected conformation.
pubmed doi rcsb |
| source organism |
Mus musculus
|
| total genus |
135
|
| structure length |
396
|
| sequence length |
463
|
| chains with identical sequence |
B
|
| ec nomenclature | |
| pdb deposition date | 2013-03-04 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00617 | RasGEF | RasGEF domain |
| A | PF00618 | RasGEF_N | RasGEF N-terminal motif |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Son of Sevenless (SoS) protein; Chain S, domain 2 | Ras guanine-nucleotide exchange factors catalytic domain | ||
| Mainly Alpha | Up-down Bundle | Son of sevenless (SoS) protein; Chain S, domain 1 | Son of sevenless (SoS) protein Chain: S domain 1 |
#chains in the Genus database with same CATH superfamily 4US0 S; 1BKD S; 4URY S; 2IJE S; 4NYJ S; 4MGY E; 3KSY A; 3QXL A; 4F7Z A; 4URV S; 2II0 A; 4US1 S; 4URX S; 1XD4 A; 3T6A A; 4L9M A; 5CM9 A; 3CF6 E; 1XD2 C; 4MGZ E; 4MH0 E; 1NVV S; 4MGI E; 4URU S; 1NVX S; 4URZ S; 5CM8 A; 2BYV E; 4NYM S; 1NVU S; 4US2 S; 4JGW A; 3T6G A; 4URW S; 1NVW S; 4MGK E; 4NYI S; #chains in the Genus database with same CATH topology 4US0 S; 1BKD S; 4URY S; 2IJE S; 4NYJ S; 4MGY E; 3KSY A; 3QXL A; 4F7Z A; 4URV S; 2II0 A; 4US1 S; 4URX S; 1XD4 A; 3T6A A; 4L9M A; 5CM9 A; 3CF6 E; 1XD2 C; 4MGZ E; 4MH0 E; 1NVV S; 4MGI E; 4URU S; 1NVX S; 4URZ S; 5CM8 A; 2BYV E; 4NYM S; 1NVU S; 4US2 S; 4JGW A; 3T6G A; 4URW S; 1NVW S; 4MGK E; 4NYI S; #chains in the Genus database with same CATH homology 4US0 S; 1BKD S; 4URY S; 2IJE S; 4NYJ S; 4MGY E; 3KSY A; 3QXL A; 4F7Z A; 4URV S; 2II0 A; 4US1 S; 4URX S; 1XD4 A; 3T6A A; 4L9M A; 5CM9 A; 3CF6 E; 1XD2 C; 4MGZ E; 4MH0 E; 1NVV S; 4MGI E; 4URU S; 1NVX S; 4URZ S; 5CM8 A; 2BYV E; 4NYM S; 1NVU S; 4US2 S; 4JGW A; 3T6G A; 4URW S; 1NVW S; 4MGK E; 4NYI S;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
