4KGOA

Crystal structure of double leucine to methionine mutant human splunc1 lacking the secretion signal sequence
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
212
structure length
183
Chain Sequence
SPTGLAGSLTNALSNGLLSGGLLGIMENLPLLDIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKMDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords BPI fold-containing family A member 1
publication title Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.
pubmed doi rcsb
source organism Homo sapiens
total genus 38
structure length 183
sequence length 212
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01273 LBP_BPI_CETP LBP / BPI / CETP family, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.15.10.10 Alpha Beta Super Roll Bactericidal permeability-increasing protein; domain 1 Bactericidal permeability-increasing protein; domain 1 4kgoA00
4F2AA 5I7JA 5I7LA 1BP1A 1EWFA 3ZPMA 4KGHA 2OBDA 4KGOA 5I7KA 4EWSA 4M4DA
chains in the Genus database with same CATH superfamily
3A1ZA 3AOSA 4KGHA 1USVB 3E8WA 2RQFA 1USUB 5I7JA 5I7LA 1EWFA 4KGOA 3E8TA 5I7KA 1BP1A 2OBDA 3N72A 4EWSA 3H4ZA 4F2AA 4G0SA 3L6IA 3UV1A 3AOTA 3ZPMA 2RCKA 4M4DA
chains in the Genus database with same CATH topology
3A1ZA 3AOSA 4KGHA 1USVB 3E8WA 2RQFA 1USUB 5I7JA 5I7LA 1EWFA 4KGOA 3E8TA 5I7KA 1BP1A 2OBDA 3N72A 4EWSA 3H4ZA 4F2AA 4G0SA 3L6IA 3UV1A 3AOTA 3ZPMA 2RCKA 4M4DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F2A A;  5I7J A;  5I7L A;  1BP1 A;  1EWF A;  3ZPM A;  4KGH A;  2OBD A;  4KGO A;  5I7K A;  4EWS A;  4M4D A; 
#chains in the Genus database with same CATH topology
 3A1Z A;  3AOS A;  4KGH A;  1USV B;  3E8W A;  2RQF A;  1USU B;  5I7J A;  5I7L A;  1EWF A;  4KGO A;  3E8T A;  5I7K A;  1BP1 A;  2OBD A;  3N72 A;  4EWS A;  3H4Z A;  4F2A A;  4G0S A;  3L6I A;  3UV1 A;  3AOT A;  3ZPM A;  2RCK A;  4M4D A; 
#chains in the Genus database with same CATH homology
 3A1Z A;  3AOS A;  4KGH A;  1USV B;  3E8W A;  2RQF A;  1USU B;  5I7J A;  5I7L A;  1EWF A;  4KGO A;  3E8T A;  5I7K A;  1BP1 A;  2OBD A;  3N72 A;  4EWS A;  3H4Z A;  4F2A A;  4G0S A;  3L6I A;  3UV1 A;  3AOT A;  3ZPM A;  2RCK A;  4M4D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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