4YKCA

Crystal structure of cerebral cavernous malformation 2 c-terminal adaptor domain
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
148
structure length
104
Chain Sequence
MELSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDWDRMISDISSDIEALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Protein binding
molecule keywords Malcavernin
publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
source organism Homo sapiens
total genus 39
structure length 104
sequence length 148
ec nomenclature
pdb deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4ykcA00
4YKDA 4YKCA 4YL6A 2LSRA 2KBQA 3K1RA 2KBRA 4FQNA 4Y5OA 5F3XA
chains in the Genus database with same CATH superfamily
4YKDA 1G1EB 1PD7A 1S5QB 2LSRA 2KBRA 2CR7A 2KBQA 4FQNA 1S5RB 3K1RA 4Y5OA 2LD7B 2L9SB 4YKCA 2RMRA 4YL6A 1E91A 2RMSA 2F05A 2CZYA 5F3XA
chains in the Genus database with same CATH topology
4YKDA 4YKCA 4YL6A 2LSRA 2KBQA 3K1RA 2KBRA 4FQNA 4Y5OA 5F3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YKD A;  4YKC A;  4YL6 A;  2LSR A;  2KBQ A;  3K1R A;  2KBR A;  4FQN A;  4Y5O A;  5F3X A; 
#chains in the Genus database with same CATH topology
 4YKD A;  1G1E B;  1PD7 A;  1S5Q B;  2LSR A;  2KBR A;  2CR7 A;  2KBQ A;  4FQN A;  1S5R B;  3K1R A;  4Y5O A;  2LD7 B;  2L9S B;  4YKC A;  2RMR A;  4YL6 A;  1E91 A;  2RMS A;  2F05 A;  2CZY A;  5F3X A; 
#chains in the Genus database with same CATH homology
 4YKD A;  4YKC A;  4YL6 A;  2LSR A;  2KBQ A;  3K1R A;  2KBR A;  4FQN A;  4Y5O A;  5F3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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