4YL6A

Crystal structure of truncated cerebral cavernous malformation 2 c-terminal adaptor domain in complex with an internal helix of mitogen-activated protein kinase kinase kinase 3
Total Genus 33
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
88
structure length
88
Chain Sequence
LSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Protein binding
molecule keywords Malcavernin
publication title Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
pubmed doi rcsb
source organism Homo sapiens
total genus 33
structure length 88
sequence length 88
ec nomenclature
pdb deposition date 2015-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4yl6A00
4YL6A 2LSRA 3K1RA 4Y5OA 4FQNA 5F3XA 4YKCA 4YKDA 2KBQA 2KBRA
chains in the Genus database with same CATH superfamily
2LSRA 3K1RA 5F3XA 2KBQA 2F05A 4YL6A 1G1EB 2CZYA 4YKCA 2L9SB 2CR7A 1PD7A 2LD7B 4YKDA 2RMSA 1E91A 1S5RB 4Y5OA 2RMRA 4FQNA 1S5QB 2KBRA
chains in the Genus database with same CATH topology
4YL6A 2LSRA 3K1RA 4Y5OA 4FQNA 5F3XA 4YKCA 4YKDA 2KBQA 2KBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YL6 A;  2LSR A;  3K1R A;  4Y5O A;  4FQN A;  5F3X A;  4YKC A;  4YKD A;  2KBQ A;  2KBR A; 
#chains in the Genus database with same CATH topology
 2LSR A;  3K1R A;  5F3X A;  2KBQ A;  2F05 A;  4YL6 A;  1G1E B;  2CZY A;  4YKC A;  2L9S B;  2CR7 A;  1PD7 A;  2LD7 B;  4YKD A;  2RMS A;  1E91 A;  1S5R B;  4Y5O A;  2RMR A;  4FQN A;  1S5Q B;  2KBR A; 
#chains in the Genus database with same CATH homology
 4YL6 A;  2LSR A;  3K1R A;  4Y5O A;  4FQN A;  5F3X A;  4YKC A;  4YKD A;  2KBQ A;  2KBR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...