Found 437 chains in Genus chains table. Displaying 1 - 50. Applied filters: Proteins

Search results query ec: 1.5.1.3

Total Genus Sequence Length pdb Title
43 159 4p3rA Cryogenic wt dhfr, time-averaged ensemble
32 162 1bzfA Nmr solution structure and dynamics of the complex of lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate, 22 structures
30 162 1ao8A Dihydrofolate reductase complexed with methotrexate, nmr, 21 structures
41 162 1diuA Dihydrofolate reductase (e.c.1.5.1.3) complex with brodimoprim-4,6-dicarboxylate
44 159 4pthA Ensemble model for escherichia coli dihydrofolate reductase at 100k
38 159 4p3qA Room-temperature wt dhfr, time-averaged ensemble
42 157 5ispX Staphylococcus aureus f98y dihydrofolate reductase mutant complexed with beta-nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
144 564 6n1tA Toxoplasma gondii ts-dhfr in complex with selective inhibitor 3
165 564 6n1sA Toxoplasma gondii ts-dhfr in complex with selective inhibitor 29
42 161 6cyvA E. coli dhfr ternary complex with nadp and dihydrofolate
43 162 6cw7A E. coli dhfr product complex with (6s)-5,6,7,8-tetrahydrofolate
37 159 6cqaA E. coli dhfr complex with inhibitor ampqd
45 165 6cxkA E. coli dhfr substrate complex with dihydrofolate
57 186 6a7eA Human dihydrofolate reductase complexed with nadph and bt2
45 162 6mr9A E. coli dhfr complex with a reaction intermediate
45 162 6mt8A E. coli dhfr complex modeled with two ligand states
41 159 4ptjA Ensemble model for escherichia coli dihydrofolate reductase at 277k
58 186 6a7cA Human dihydrofolate reductase complexed with nadph and bt1
42 157 5isqX Staphylococcus aureus h30n, f98y dihydrofolate reductase mutant complexed with beta-nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
42 157 5istX Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph, cyclic alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
169 608 3um8A Wild-type plasmodium falciparum dhfr-ts complexed with cycloguanil and nadph
46 164 3sa1A Bacuills anthracis dihydrofolate reductase bound propargyl-linked tmp analog, ucp1021
43 165 3s9uA Bacillus anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, ucp120j
45 165 3sa2A Bacuills anthracis dihydrofolate reductase bound propargyl-linked tmp analog, ucp1014
45 165 3saiA Bacuills anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, ucp1015
45 162 6mthA E. coli dhfr complex modeled with three ligand states
41 157 5jg0X Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph and ucp1191
43 159 5ja3A Mycobacterium tuberculosis dihydrofolate reductase complexed with beta- nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-b iphenyl]-4-carboxylic acid (ucp1106)
54 186 5hvbA 5-methyl-6-(1-naphthylthio)thieno[2,3-d]pyrimidine 2,4-diamine
57 186 5hsrA Fluorine substituted 5-methyl-6-(3',4'-difluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine
60 186 5hveA 5-methyl-6-(3'-trifluromethoxyphenylthio)[2,3-d]pyrimidine 2,4-diamine
50 186 5hpbA Human dihydrofolate reductase complex with nadph and 5-methyl-6-(phenylthio-4'trifluoromethyl)thieno[2,3-d]pyrimidine-2,4-diamine
53 186 5ht5A 6-substituted pyrrolo[2,3-d]pyrimidine 6-thieno-(4-methoxyphenyl)
53 186 5hqyA Human dihydrofolate reductase complex with nadph and 5-methyl-6-(2',3',4'-trifluorophenylthio)thieno[2,3-d]pyrimidine-2,4-diamine
56 186 5hsuA Fluorine substituted 5-methyl-6-(2',4'-difluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine
53 186 5huiA 6-substituted pyrido[3,2-d]pyrimidine--6-4'-trifluoromethoxyphenyl)
55 186 5hqzA Fluorine substituted 5-methyl-6-(4'-trifluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine
54 186 8dfrA Refined crystal structures of chicken liver dihydrofolate reductase. 3 angstroms apo-enzyme and 1.7 angstroms nadph holo-enzyme complex
40 159 7dfrA Crystal structures of escherichia coli dihydrofolate reductase. the nadp+ holoenzyme and the folate(dot)nadp+ ternary complex. substrate binding and a model for the transition state
42 159 6e4eA Crystal structure of dihydrofolate reductase from staphylococcus aureus mw2 bound to nadp and p218
41 159 6ddsA Mycobacterium tuberculosis dihydrofolate reductase complexed with beta-nadph and 4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-5-methoxy-phenyl]benzoic acid
57 186 6davA Crystal structure of human dhfr complexed with nadp and n10formyltetrahydrofolate
44 159 6ddwA Mycobacterium tuberculosis dihydrofolate reductase complexed with beta-nadph and n-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-2-hydroxybenzene-1-carbonyl)-l-glutamic acid
42 159 6ddpA Mycobacterium tuberculosis dihydrofolate reductase complexed with beta-nadph and 3'-[(2r)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-5'-methoxy[1,1'-biphenyl]-4-carboxylic acid
53 186 6de4A Homo sapiens dihydrofolate reductase complexed with beta-nadph and 3'-[(2r)-4-(2,4-diamino-6-ethylphenyl)but-3-yn-2-yl]-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid
40 159 6dfrA Crystal structures of escherichia coli dihydrofolate reductase. the nadp+ holoenzyme and the folate(dot)nadp+ ternary complex. substrate binding and a model for the transition state
38 155 6cxmA Crystal structure of a dihydrofolate reductase from mycobacterium smegmatis in complex with nadp and p218
158 564 6aogA Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf, and 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine (pyrimethamine)
154 564 6aoiA Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf, and 5-(4-phenylpiperazin-1-yl)-6-propylpyrimidine-2,4-diamine (trc-2528)
144 564 6aohA Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf, and 5-(4-(3-(2-methoxypyrimidin-5-yl)phenyl)piperazin-1-yl)pyrimidine-2,4-diamine (trc-2533)