|
128
|
390
|
7nq4A |
Human trna guanine transglycosylase (tgt), rna-bound covalent intermediate |
|
138
|
377
|
7adnA |
Apo trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant |
|
137
|
376
|
7a0bA |
Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with rac-trans-3,4-dihydroxysulfolane |
|
141
|
383
|
7a4kA |
Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with tetramethylene sulfoxide |
|
136
|
377
|
7a3vA |
Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with 3-hydroxysulfolane |
|
137
|
377
|
7a6dA |
Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with rac-trans-4,4-difluorocyclopentane-1,2-diol |
|
138
|
378
|
7a4xA |
Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with dimethyl sulfoxide |
|
125
|
374
|
7a3xA |
Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with sulfolane |
|
135
|
381
|
7a9eA |
Trna-guanine transglycosylase c158s/c281s/y330c/h333a mutant in complex with ethyl methyl sulfone |
|
134
|
373
|
7apmA |
Trna-guanine transglycosylase h319c mutant spin-labeled with mtsl |
|
131
|
375
|
7aplA |
Trna-guanine transglycosylase g87c mutant spin-labeled with mtsl |
|
136
|
373
|
6z0dA |
Trna-guanine transglycosylase (tgt) h333f mutant crystallised at ph 5.5 |
|
129
|
374
|
6yyzA |
Trna-guanine transglycosylase (tgt) labeled with 5-fluorotryptophan in co-crystallized complex with 6-amino-2-(methylamino)-4-(2-((2r,3r,4r,5r)-3,4,5-trimethoxytetrahydrofuran-2-yl)ethyl)-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
134
|
374
|
6rkqA |
Crystal structure of tgt in complex with n2-methyl-8-(prop-1-yn-1-yl)-3h,7h,8h-imidazo[4,5-g]quinazoline-2,6-diamine |
|
127
|
374
|
6rktA |
Crystal structure of tgt in complex with n2-methyl-1h,7h,8h-imidazo[4,5-g]quinazoline-2,6-diamine |
|
135
|
376
|
1q2rA |
Chemical trapping and crystal structure of a catalytic trna guanine transglycosylase covalent intermediate |
|
134
|
376
|
1q2sA |
Chemical trapping and crystal structure of a catalytic trna guanine transglycosylase covalent intermediate |
|
136
|
373
|
6fmnA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-2-((((2r,3s,4r,5r)-3,4-dihydroxy-5-methoxytetrahydrofuran-2-yl)methyl)amino)-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
133
|
373
|
6fpuA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-2-((((3as,5ar,8bs)-2,2,7,7-tetramethyltetrahydro-3ah-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl)amino)-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
139
|
373
|
6fsoA |
Crystal structure of tgt in complex with methyl({[5-(pyridin-3-yloxy)furan-2-yl]methyl})amine |
|
138
|
374
|
5j9mA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 2-(methylamino)-1h-benzo[d]imidazole-5-carboxamide |
|
132
|
375
|
5n6fA |
Crystal structure of tgt in complex with guanine fragment |
|
131
|
377
|
5lpqA |
Trna guanine transglycosylase (tgt) in co-crystallized complex (space group p21) with 6-amino-4-(2-((3ar,4r,6r,6ar)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethyl)-2-(methylamino)-1h-imidazo[4,5-g]quinazolin-8(7h)-one |
|
129
|
377
|
5lptA |
Trna guanine transglycosylase (tgt) in co-crystallized complex (space group p21) with 6-amino-2-(methylamino)-4-(2-((2r,3r,4s,5r,6s)-3,4,5,6-tetramethoxytetrahydro-2h-pyran-2-yl)ethyl)-1h-imidazo[4,5-g]quinazolin-8(7h)-one |
|
136
|
374
|
5lpoA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-2-(methylamino)-4-(2-((2r,3r,4r,5r)-3,4,5-trimethoxytetrahydrofuran-2-yl)ethyl)-1h-imidazo[4,5-g]quinazolin-8(7h)-one |
|
127
|
374
|
5lppA |
Trna guanine transglycosylase (tgt) in co-crystallized complex (space group c2) with 6-amino-4-(2-((3ar,4r,6r,6ar)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethyl)-2-(methylamino)-1h-imidazo[4,5-g]quinazolin-8(7h)-one |
|
122
|
373
|
5lpsA |
Trna guanine transglycosylase (tgt) in co-crystallized complex (space group c2) with 6-amino-2-(methylamino)-4-(2-((2r,3r,4s,5r,6s)-3,4,5,6-tetramethoxytetrahydro-2h-pyran-2-yl)ethyl)-1h-imidazo[4,5-g]quinazolin-8(7h)-one |
|
145
|
374
|
5jsvA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-2-((((3ar,4r,6r,6ar)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)amino)-1h-imidazo[4,5-g]quinazolin-8(7h)-one |
|
129
|
373
|
5j9nA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 2-(methylamino)-1h-benzo[d]imidazole-5-carbohydrazide |
|
142
|
374
|
5jxqA |
Trna-guanine transglycosylase (tgt) in complex with 6-amino-2-{[4-(2-hydroxyethyl)phenethyl]amino}-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
141
|
374
|
5jgoA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with allyl (2-(methylamino)-8-oxo-7,8-dihydro-1h-imidazo[4,5-g]quinazolin-6-yl)carbamate |
|
146
|
374
|
5jswA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-2-((((3a'r,6'r,6a'r)-2,2,2',2'-tetramethyldihydro-3a'h-spiro[[1,3]dioxolane-4,4'-furo[3,4-d][1,3]dioxol]-6'-yl)methyl)amino)-1h-imidazo[4,5-g]quinazolin-8(7h)-one |
|
134
|
374
|
5jt6A |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 2-((2-morpholinoethyl)amino)-1h-benzo[d]imidazole-5-carbohydrazide |
|
136
|
374
|
5jgmA |
Trna guanine transglycosylase (tgt) in co-crystallized complex with ethyl (2-(methylamino)-8-oxo-7,8-dihydro-1h-imidazo[4,5-g]quinazolin-6-yl)carbamate |
|
134
|
373
|
5jt7A |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 1-(2-((2-morpholinoethyl)amino)-1h-benzo[d]imidazol-6-yl)guanidine |
|
136
|
375
|
5i03A |
Trna-guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-4-[2-(4-methylphenyl)ethyl]-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
139
|
376
|
5i07A |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-4-(2-phenylethyl)-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
135
|
376
|
5i02A |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
133
|
375
|
5i06A |
Trna-guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-4-[2-(4-methoxyphenyl)ethyl]-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
141
|
374
|
5i00A |
Trna guanine transglycosylase (tgt) in co-crystallized complex with 6-amino-4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8h-imidazo[4,5-g]quinazolin-8-one |
|
142
|
374
|
5i09A |
Trna guanine transglycosylase (tgt) in soaked complex with furanoside-based lin-benzoguanine 3 |
|
134
|
392
|
6h45A |
Crystal structure of the human tgt catalytic subunit qtrt1 in complex with queuine |
|
131
|
393
|
6h42A |
Crystal structure of the human tgt catalytic subunit qtrt1 |
|
135
|
375
|
5v3cA |
Crystal structure of tgt in complex with 4-(aminomethane)cyclohexane-1-carboxylic acid |
|
140
|
373
|
4q8vA |
Trna-guanine transglycosylase (tgt) in complex with 4-[2-({6-amino-8-oxo-1h,7h,8h-imidazo[4,5-g]quinazolin-2-yl}amino)ethyl]benzonitrile |
|
132
|
373
|
4hvxA |
Trna-guanine transglycosylase y106f, c158v mutant in complex with queuine |
|
134
|
373
|
4q8oA |
Trna-guanine transglycosylase (tgt) mutant v262t in complex with 6-amino-2-{[2-(morpholin-4-yl)ethyl]amino}-1h,7h,8h-imidazo[4,5-g]quinazolin-8-one |
|
137
|
373
|
4q8tA |
Trna-guanine transglycosylase (tgt) in complex with 6-amino-2-[(2-phenylethyl)amino]-1h,7h,8h-imidazo[4,5-g]quinazolin-8-one |
|
137
|
373
|
4dy1A |
Trna-guanine transglycosylase f92c c158s c281s mutant |
|
140
|
373
|
4dxxA |
Tgt k52m mutant crystallized at ph 8.5 |
