|
78
|
242
|
8v74A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 10 |
|
80
|
242
|
8v6yA |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 3 |
|
77
|
242
|
8v79A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 15 |
|
79
|
242
|
8v70A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 6 |
|
84
|
242
|
8v6xA |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 2 |
|
79
|
242
|
8v71A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 7 |
|
80
|
242
|
8v76A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 12 |
|
82
|
242
|
8v6zA |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 4 |
|
81
|
242
|
8v75A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 11 |
|
79
|
242
|
8v6wA |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 1 |
|
81
|
242
|
8v72A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 8 |
|
79
|
242
|
8v78A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 14 |
|
80
|
242
|
8v77A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 13 |
|
77
|
242
|
8v73A |
Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 9 |
|
39
|
142
|
9b4uA |
Crystal structure of p110alpha-rbd covalently bound to a breaker compound bbo-10203 via cys242 |
|
268
|
1036
|
9lwrA |
Cryo-em structure of pi3kalpha h1047r in complex with compound ucl-tro-1938 |
|
247
|
1033
|
9lwqA |
Cryo-em structure of pi3kalpha in complex with compound ucl-tro-1938 |
|
260
|
946
|
9cmvA |
Crystal structure of the kras-p110alpha complex in the presence of molecular glue d223 |
|
34
|
135
|
9cmkA |
Crystal structure of p110alpha-ras binding domain (rbd) in complex with molecular glue d927 |
|
35
|
135
|
9cmlA |
Crystal structure of p110alpha-ras binding domain (rbd) in complex with molecular glue d223 |
|
234
|
1032
|
8w9aA |
Cryoem structure of human pi3k-alpha (p85/p110-h1047r) with qr-7909 binding at an allosteric site |
|
249
|
1056
|
8sobA |
Phosphoinositide phosphate 3 kinase gamma bound with adp |
|
242
|
1056
|
8so9A |
Phosphoinositide phosphate 3 kinase gamma |
|
295
|
1063
|
8v8jA |
Pi3ka h1047r co-crystal structure with inhibitors in two cryptic pockets (compounds 4 and 5). |
|
333
|
1048
|
8v8vA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket near h1047r (compound 7). |
|
328
|
1068
|
8v8uA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket near h1047r (compound 12). |
|
299
|
1063
|
8v8hA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket near h1047r (compound 4). |
|
290
|
1058
|
8v8iA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket (compound 5). |
|
291
|
926
|
6zadA |
Pi3k delta in complex with methoxymethyloxathiatetraazatetracyclodocosahexaenedione |
|
277
|
1044
|
7mynA |
Cryo-em structure of p110alpha in complex with p85alpha |
|
245
|
1033
|
7myoA |
Cryo-em structure of p110alpha in complex with p85alpha inhibited by byl-719 |
|
294
|
1018
|
7lq1A |
Human pi3kdelta in complex with compound 28 |
|
311
|
1061
|
8am0A |
Crystal structure of human t1061e pi3kalpha in complex with its regulatory subunit and the inhibitor gdc-0077 (inavolisib) |
|
321
|
1041
|
8ts7A |
Human pi3k p85alpha/p110alpha |
|
321
|
1043
|
8tsbA |
Human pi3k p85alpha/p110alpha bound to compound 2 |
|
323
|
1045
|
8tsdA |
Human pi3k p85alpha/p110alpha bound to rly-2608 |
|
327
|
1049
|
8tsaA |
Human pi3k p85alpha/p110alpha h1047r bound to compound 2 |
|
332
|
1045
|
8ts9A |
Human pi3k p85alpha/p110alpha h1047r bound to compound 1 |
|
294
|
1154
|
7bi2A |
Pi3kc2adeltan and deltac-c2 |
|
260
|
894
|
7bi4A |
Pi3kc2a core apo |
|
249
|
896
|
7bi6A |
Pi3kc2a core in complex with atp |
|
247
|
894
|
7bi9A |
Pi3kc2a core in complex with pik90 |
|
266
|
939
|
7r9yA |
Structure of pik3ca with covalent inhibitor 22 |
|
268
|
939
|
7r9vA |
Structure of pik3ca with covalent inhibitor 19 |
|
257
|
919
|
7r2bA |
Pi3kdelta in complex with an inhibitor |
|
281
|
940
|
7mlkA |
Crystal structure of human pi3ka (p110a subunit) with mmv085400 bound to the active site determined at 2.9 angstroms resolution |
|
305
|
1052
|
8sbcA |
Co-structure of phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and brain penetrant inhibitors |
|
324
|
1062
|
8tgdA |
Stx-478, a mutant-selective, allosteric inhibitor bound to h1047r pi3kalpha |
|
318
|
1060
|
8tduA |
Stx-478, a mutant-selective, allosteric inhibitor bound to pi3kalpha |
|
295
|
1032
|
8tu6A |
Cryoem structure of pi3kalpha |
