|
234
|
1032
|
8w9aA |
Cryoem structure of human pi3k-alpha (p85/p110-h1047r) with qr-7909 binding at an allosteric site |
|
249
|
1056
|
8sobA |
Phosphoinositide phosphate 3 kinase gamma bound with adp |
|
242
|
1056
|
8so9A |
Phosphoinositide phosphate 3 kinase gamma |
|
295
|
1063
|
8v8jA |
Pi3ka h1047r co-crystal structure with inhibitors in two cryptic pockets (compounds 4 and 5). |
|
333
|
1048
|
8v8vA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket near h1047r (compound 7). |
|
328
|
1068
|
8v8uA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket near h1047r (compound 12). |
|
299
|
1063
|
8v8hA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket near h1047r (compound 4). |
|
290
|
1058
|
8v8iA |
Pi3ka h1047r co-crystal structure with inhibitor in cryptic pocket (compound 5). |
|
291
|
926
|
6zadA |
Pi3k delta in complex with methoxymethyloxathiatetraazatetracyclodocosahexaenedione |
|
277
|
1044
|
7mynA |
Cryo-em structure of p110alpha in complex with p85alpha |
|
245
|
1033
|
7myoA |
Cryo-em structure of p110alpha in complex with p85alpha inhibited by byl-719 |
|
294
|
1018
|
7lq1A |
Human pi3kdelta in complex with compound 28 |
|
311
|
1061
|
8am0A |
Crystal structure of human t1061e pi3kalpha in complex with its regulatory subunit and the inhibitor gdc-0077 (inavolisib) |
|
321
|
1041
|
8ts7A |
Human pi3k p85alpha/p110alpha |
|
321
|
1043
|
8tsbA |
Human pi3k p85alpha/p110alpha bound to compound 2 |
|
323
|
1045
|
8tsdA |
Human pi3k p85alpha/p110alpha bound to rly-2608 |
|
327
|
1049
|
8tsaA |
Human pi3k p85alpha/p110alpha h1047r bound to compound 2 |
|
332
|
1045
|
8ts9A |
Human pi3k p85alpha/p110alpha h1047r bound to compound 1 |
|
294
|
1154
|
7bi2A |
Pi3kc2adeltan and deltac-c2 |
|
260
|
894
|
7bi4A |
Pi3kc2a core apo |
|
249
|
896
|
7bi6A |
Pi3kc2a core in complex with atp |
|
247
|
894
|
7bi9A |
Pi3kc2a core in complex with pik90 |
|
266
|
939
|
7r9yA |
Structure of pik3ca with covalent inhibitor 22 |
|
268
|
939
|
7r9vA |
Structure of pik3ca with covalent inhibitor 19 |
|
257
|
919
|
7r2bA |
Pi3kdelta in complex with an inhibitor |
|
281
|
940
|
7mlkA |
Crystal structure of human pi3ka (p110a subunit) with mmv085400 bound to the active site determined at 2.9 angstroms resolution |
|
305
|
1052
|
8sbcA |
Co-structure of phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and brain penetrant inhibitors |
|
324
|
1062
|
8tgdA |
Stx-478, a mutant-selective, allosteric inhibitor bound to h1047r pi3kalpha |
|
295
|
1032
|
8tu6A |
Cryoem structure of pi3kalpha |
|
318
|
1060
|
8tduA |
Stx-478, a mutant-selective, allosteric inhibitor bound to pi3kalpha |
|
248
|
1044
|
8ilsA |
Cryo-em structure of pi3kalpha in complex with compound 17 |
|
249
|
1044
|
8ilrA |
Cryo-em structure of pi3kalpha in complex with compound 16 |
|
236
|
1044
|
8ilvA |
Cryo-em structure of pi3kalpha in complex with compound 18 |
|
304
|
1053
|
8sbjA |
Co-structure phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform complexed with brain penetrant inhibitors |
|
284
|
1052
|
8dp0A |
Structure of p110 gamma bound to the ras inhibitory nanobody nb7 |
|
271
|
941
|
8ow2A |
Crystal structure of the p110alpha catalytic subunit from homo sapiens in complex with activator 1938 |
|
299
|
1012
|
8bcyA |
Human pi3kdelta in complex with compound 13 |
|
333
|
1043
|
8aj8A |
Structure of p110 gamma bound to the p84 regulatory subunit |
|
291
|
940
|
8bfuA |
Crystal structure of the apo p110alpha catalytic subunit from homo sapiens |
|
231
|
944
|
8guaA |
Cryo-em structure of cancer-specific pi3kalpha mutant e542k in complex with byl-719 |
|
307
|
1051
|
7tz7A |
Pi3k alpha in complex with an inhibitor |
|
310
|
945
|
8exvA |
Crystal structure of pi3k-alpha in complex with compound 32 |
|
319
|
945
|
8exuA |
Crystal structure of pi3k-alpha in complex with compound 30 |
|
306
|
945
|
8exoA |
Crystal structure of pi3k-alpha in complex with compound 19 |
|
305
|
945
|
8exlA |
Crystal structure of pi3k-alpha in complex with taselisib |
|
288
|
1032
|
8gubA |
Cryo-em structure of cancer-specific pi3kalpha mutant h1047r in complex with byl-719 |
|
206
|
944
|
8gudA |
Cryo-em structure of cancer-specific pi3kalpha mutant e545k in complex with byl-719 |
|
291
|
1034
|
8dcpA |
Pi 3-kinase alpha with nanobody 3-126 |
|
222
|
1031
|
8dcxA |
Pi 3-kinase alpha with nanobody 3-159 |
|
244
|
1041
|
8dd4A |
Pi 3-kinase alpha with nanobody 3-142 |
